DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment rib and CG34376

DIOPT Version :9

Sequence 1:	NP_001261085.1	Gene:	rib / 44855	FlyBaseID:	FBgn0003254	Length:	680	Species:	Drosophila melanogaster
Sequence 2:	NP_732741.1	Gene:	CG34376 / 42638	FlyBaseID:	FBgn0085405	Length:	681	Species:	Drosophila melanogaster

Alignment Length:	728	Identity:	168/728 - (23%)
Similarity:	243/728 - (33%)	Gaps:	227/728 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 LRWNNHQTNLVQILHALHEVGSYVDCSLVVDDEQFQAHRVVLAANSPYFQHILKDVPQDHCSIIL 84
            |.|.|.|.|:......|::.|..||.:|..|.:...||::|||..|||||.|....|..|..|||
  Fly     7 LCWKNFQDNIASGFQNLYDRGDLVDVTLACDGKLLHAHKIVLAICSPYFQEIFTTNPCKHPIIIL 71

  Fly    85 PGVKGFEIAALLQYMYTGETTVTKSQEPEILRTAKELQVKGLYDNLMKFNHASVTPTSSSGAGGA 149
            ..|....:..||::||.|...|..::....::..:.||:|||..|......:||:..|||.....
  Fly    72 KDVSFNIMMELLEFMYQGVVNVKHTELQSFMKIGQLLQIKGLATNSNSSPGSSVSEKSSSQPPAE 136

  Fly   150 KPQNGSASNHSSSVI------------------STSTHISPSAA---------ISSSCSPPPPPQ 187
            :..|.:::||.:|..                  |.|...||..|         :.:|...|.|..
  Fly   137 ESSNTNSTNHHNSSTNSNNNSKSETDHNESKGQSNSRTTSPGGASRASNDASHLYTSNKRPMPSD 201

  Fly   188 FGYQPGYSHYPQQQPMSASQIPAGEAPLTPTQATPHSAASGAGEAGGQWPLTPSAAAAMLNSVY- 251
            || ....|.|..:|                .:.:.....||..|.||  ......||.:.||:.
  Fly   202 FG-SDSLSIYSGKQ----------------LRRSLKDHGSGGSEGGG--GDHADTAAGLDNSMNS 247

  Fly   252 --------------ESAADMNPLKRKK-------LSA-------ISSMLLSGNRDTPILRNVLA- 287
                          |...|:..|||:.       |||       :.|:..|.:...|| ||..|
  Fly   248 EEFFLPPIPQITMGEQRYDLGGLKRESDGHHHGPLSAGGGNSGSVGSLTSSASPSAPI-RNPFAP 311

  Fly   288 -------------QANPADSSQ----PGPMNANGEKTPTHPHQNTQLPAGLGVSGGE-RNHSFNG 334
                         .:.|:.||.    ||.:|.||.             .||| ||.| .|..:..
  Fly   312 NFMDSFNYYKGGNSSGPSGSSNNSVGPGGVNNNGS-------------VGLG-SGAEYPNELYMP 362

  Fly   335 SDY-------------GGDKEPLSPYT--------DRSFEEETGQSGGKKPEW--KRYKQYTRAD 376
            :||             |.:...||..:        :|:....|.|  |.|..|  |.|:     .
  Fly   363 NDYSKSFANHMDIPSSGSNMVMLSTTSLLHGNCVFNRNNTVATQQ--GMKTYWLCKSYR-----I 420

  Fly   377 MMCAIQAVR---------------------EGMSALQASRKYGLPSRTLYDKVRKLNITTGRG-- 418
            .||..:.:.                     :|.||...:...|.|:.|........::|.|.|
  Fly   421 SMCRARCITHLGRIISATGVHNHTPHMRGGQGSSAPSTASVSGNPAPTPISSQAGYSLTDGGGHL 485

  Fly   419 --------------THRTPKRSPPGAESSQGFSYSAAAAAAAHNYGHGHGHHSEVKRDQKVDHVP 469
                          .::||...||.         .....|:..::.|.|.|..:...:..|.|.|
  Fly   486 GPDLQHGNRVTNMFANQTPPPPPPP---------PPLPVASTPHHPHHHHHLGQPLPNLLVQHHP 541

  Fly   470 A-----HHGMPPTIPPSAAALL-----------DHAFLQQALENRGGDMAGREALHAMALAAAAH 518
            |     .||       |:|:||           .|...||..:............|.:.|...:.
  Fly   542 APSHMEQHG-------SSASLLHNPNLMHLQTPTHHHQQQHHQQHSPHNPPPPQQHNLELGGGSG 599

  Fly   519 AAANRLSSSPAEMDQRSN--GHGMRSPSPQGRHYPHEQEAMDLEMEKHEQNIIKRERDQDEREDA 581
            :.|..||.:..:...:||  .|.:::.||.    |...|    |.:.|:|       .|.::|.|
  Fly   600 SGAVLLSPAHLQQSPQSNRSSHSLQAQSPP----PQSVE----EQQPHQQ-------QQQQQEGA 649

  Fly   582 DDE--EDHEQEHV 592
            ..|  .|....||
  Fly   650 TTEVTTDPSTAHV 662

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rib	NP_001261085.1	BTB	33..133	CDD:279045	35/99 (35%)
		BTB	44..133	CDD:197585	32/88 (36%)
		HTH_psq	373..417	CDD:283007	9/64 (14%)
CG34376	NP_732741.1	BTB	20..113	CDD:279045	32/92 (35%)
		BTB	31..115	CDD:197585	31/83 (37%)
		FLYWCH	390..443	CDD:282369	10/59 (17%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1229475at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23110
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	3.020