DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment rib and CG6765

DIOPT Version :9

Sequence 1:	NP_001261085.1	Gene:	rib / 44855	FlyBaseID:	FBgn0003254	Length:	680	Species:	Drosophila melanogaster
Sequence 2:	NP_001261582.1	Gene:	CG6765 / 38971	FlyBaseID:	FBgn0035903	Length:	681	Species:	Drosophila melanogaster

Alignment Length:	802	Identity:	159/802 - (19%)
Similarity:	253/802 - (31%)	Gaps:	337/802 - (42%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 QTYCLRWNNHQTNLVQILHALHEVGSYVDCSLV-----------VDDEQFQAHRVVLAANSPYFQ 69
            :.|.|:|::|.|.|...:..|::...:.|..|.           :......||:.:|:|:|.:|.
  Fly     4 ENYHLKWDSHLTYLNSSIATLYKNEKFADVVLYSSYNSSGIPSDIPTVGISAHKFILSASSQFFA 68

  Fly    70 HILKDVPQDHCSIIL-----PGVKGFEIAALLQYMYTGETTVTKSQEPEILRTAKELQVKGLYDN 129
            .:.:..|..:.:.:|     |.:....|..|:||||:||.||:.....|:||..:.|:::||
  Fly    69 TMFETAPITNPNGVLYVVLPPDLSHRAIQILVQYMYSGEATVSNDILNEVLRGGEILKIRGL--- 130

  Fly   130 LMKFNHASVTPTSSSGAGGAKPQNGSASNHSSSVIST-------STHISPSAAISSSCS------ 181
                     ..||||..||           |.||::|       :.|:.|..|.:...|
  Fly   131 ---------CRTSSSNGGG-----------SGSVVTTTHHPHSLAGHLHPREASTMYMSNGTRTA 175

  Fly   182 ---PPPPPQ-----------FGYQPGYS-------------------HYPQQQ--PMSASQIPAG 211
               ||||||           :..:||.|                   |.||||  .:.||.:|.
  Fly   176 LPPPPPPPQSTMSAQLQGDLYASKPGGSTRFALDHHHLSSHHSHLNHHNPQQQFRGLGASVMPK- 239

  Fly   212 EAPLTPTQATPHSAASGAGEAGGQWPLTPSAAAAMLNSVYESAADMNPLKRKKLSAISSML---- 272
            ::|:.                                           :|..||:|.:.:|
  Fly   240 DSPVI-------------------------------------------IKSPKLAAHTGLLTVAS 261

  Fly   273 -----LSGNRDTPILRNVLAQANPADS---SQPGPMNANGEKTPTHPHQNTQLPAGLGVSGGERN 329
                 :|.|::..|        :|.|.   :.||.:     ::.:||...|.....:|..||
  Fly   262 SSKLGISVNKEVAI--------DPEDKCCFAAPGQL-----ESQSHPPPPTTTTTTVGGGGG--- 310

  Fly   330 HSFNGSDYGGDKEPLSPYTD---RSFEEETGQSGGKKPEWKRYKQYTRADMMCAIQAVRE----G 387
             |..||. ....:|:|..|:   .|.....|....:.....|..:|..       ||:||    |
  Fly   311 -SVGGSG-APPSQPISICTEVGCSSCPLTAGPGADQAETTLRRTEYEE-------QALRERNEVG 366

  Fly   388 M---------SALQASRKYGLPSRTLYDKVRKLNITTGR-----------------GTHRTP--- 423
            :         ||.:.||.|       |:.....::.:.|                 .|.|.|
  Fly   367 LVFERRLRRESACERSRDY-------YEAPHFEHVVSSRLAATPPPPPQQAPPSHPPTLRHPHNF 424

  Fly   424 ----------KRSPPGAESSQG-----------------FSYSAAAAAAAHNYGHGHGHHSEVKR 461
                      ..:||.|.|:..                 |..||...              ||.|
  Fly   425 LTIKQEPTDWSNNPPNASSASNNNNLEELPLASPKQPLDFKMSAVKL--------------EVNR 475

  Fly   462 DQKVDHVPAHHGMPPTIPP--SAAALL----------DHAFLQQALENRGGDMAG---REALHAM 511
            |:   ..|:......|:..  :...||          |...|.:.|....||..|   |..|.:.
  Fly   476 DR---GTPSEESEEHTLRDYNNFKQLLVCEICQKSFEDTKMLVRHLGTHAGDPTGGTERNLLPSS 537

  Fly   512 ALAAAAHAAAN---------------RLSSSPAEMDQRSNGH----------GMRSPSPQGRHYP 551
            |..:...|::|               |:|.....||   :.|          ...:|:...||..
  Fly   538 ASGSTTSASSNLALRSVKTYVPKKRRRVSQQENNMD---HDHVTLLCDLCSTSFDTPAEWVRHMN 599

  Fly   552 HEQEAMDLEMEKHEQNIIKRERDQDEREDADDEEDHEQEHVEDLSLARKERPPSPYSPQPTEAGA 616
            .:...::|.|                   .:.::|.||         :.::||    |.|..:
  Fly   600 SQHTEIELAM-------------------FNSKKDGEQ---------KGQQPP----PPPATS-- 630

  Fly   617 GVIMHASSASANGKDHVDYPSS 638
                 :||..:|.:....||||
  Fly   631 -----SSSTVSNSQMQPKYPSS 647

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rib	NP_001261085.1	BTB	33..133	CDD:279045	28/115 (24%)
		BTB	44..133	CDD:197585	27/104 (26%)
		HTH_psq	373..417	CDD:283007	11/56 (20%)
CG6765	NP_001261582.1	BTB	24..132	CDD:279045	28/119 (24%)
CG6765	NP_001261582.1	BTB	53..130	CDD:197585	23/76 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23110
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010