DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment rib and CG32121

DIOPT Version :9

Sequence 1:	NP_001261085.1	Gene:	rib / 44855	FlyBaseID:	FBgn0003254	Length:	680	Species:	Drosophila melanogaster
Sequence 2:	NP_001097599.1	Gene:	CG32121 / 317867	FlyBaseID:	FBgn0052121	Length:	648	Species:	Drosophila melanogaster

Alignment Length:	741	Identity:	179/741 - (24%)
Similarity:	252/741 - (34%)	Gaps:	248/741 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 QTYCLRWNNHQTNLVQILHALHEVGSYVDCSLVVDDEQFQAHRVVLAANSPYFQHILKDV-PQDH 79
            |.:||||:||||:|:..|..|.:.....|.::..:..|.:||||||:|.|.:|..|.:.: ..:|
  Fly    28 QQFCLRWHNHQTSLLSTLPILLDQSHLTDVTISAEGRQLRAHRVVLSACSSFFMDIFRALEASNH 92

  Fly    80 CSIILPGVKGFEIAALLQYMYTGETTVTKSQEPEILRTAKELQVKGLYD----NLMKFNHASVTP 140
            ..||:||.....|.:||.:||:||..|.:.|.|.:|..|:.|.:|||.|    ||.|
  Fly    93 PVIIIPGASFGAIVSLLTFMYSGEVNVYEEQIPMLLNLAETLGIKGLADVQNNNLPK-------- 149

  Fly   141 TSSSGAGGAKPQNGSASNHSSSVISTSTHISPSAAISSSCSPPPPPQFGYQPGYSHYPQQQPMSA 205
            |:.||.|...    ..:|..||.....|            :|.|.|.....|  ||.|
  Fly   150 TARSGGGSYM----DTTNEKSSEFERPT------------TPSPTPTPTLTP--SHTP------- 189

  Fly   206 SQIPAGEAPLTPTQATPHSAASGAGEAGGQWPLTPSAAAAMLNSVYESAADMNPLKRKKLSAISS 270
                      ||:.:.|             .|..||||   ||:         ||...||.:::|
  Fly   190 ----------TPSHSLP-------------LPQLPSAA---LNT---------PLLANKLGSVNS 219

  Fly   271 MLLSGNRDTPILRNVLAQANPADSSQPGPMNANGEKTPTHPHQNTQLPA------GLGVSGGERN 329
               ||...|| |.|:........|..|.|:|.    :.|..::.|:|.|      .|..||.:.:
  Fly   220 ---SGMGTTP-LENLFKSLQFYPSLLPQPLNF----SQTALNKTTELLAKYQQQCQLYQSGMQED 276

  Fly   330 H----SFNGSDYGGD--------------KEPLSPYTDRSFEEETGQSGGKKPEWKRYKQYTRAD 376
            .    .|......||              |.|.|..|       |..|..|.|:     :.:..:
  Fly   277 QLETDCFGSKRLKGDSPPKELRRLEKSLLKNPKSSST-------TNSSSSKSPQ-----ECSNPN 329

  Fly   377 MMCAIQAVREGMSALQ-----------ASRKYGLPSRTLYDKVRKLNITTGRGTHRTPKRSPPGA 430
            .:.|...|......:.           :|..|  ||            ..|:|...:.|  ||
  Fly   330 PIVATSPVTLAPPTMAHFSPQLPVVKCSSASY--PS------------ALGQGQLYSSK--PP-- 376

  Fly   431 ESSQGFSYSAAAA-AAAHNYGHGHGHHSEVKRDQKVDHVPAHHGMPPTIPPSAAALLDHAFLQQA 494
                  .||||.. .||......|                 ||..|...|..:|.  |||.||..
  Fly   377 ------LYSAAVTPTAAQQAAQMH-----------------HHPQPGPSPYISAE--DHAKLQLH 416

  Fly   495 LENRGGDMAGREALHAMALAA------AAHAAANRLSSSPAEMDQRSNGHGMRSPSPQGRHYP-- 551
            :|     ...|||..|.|.||      :|.:..|.||.| |:.|:......::.|| ..:.|.
  Fly   417 IE-----QYQREAAAAAAAAAGGMALVSAKSEPNLLSLS-ADRDKSLATAPIKPPS-NSKLYATC 474

  Fly   552 ---HEQEAMDLEMEKH---EQNI---------IKRERDQDERE------DADDEEDHEQEHVEDL 595
               |:|.:....:..|   .||:         :.|.:|...:.      .|....::|.......
  Fly   475 FICHKQLSNQYNLRVHLETHQNVRYACNVCSHVSRSKDALRKHVSYRHPGAPSPCENEARRKRVS 539

  Fly   596 SLARKERPPS---------------------------------PYSPQPTE----AGAGVIMHAS 623
            .||....|.|                                 ||...|.:    |.|..:..|.
  Fly   540 KLAATTVPTSTPMSMSASHTVTSGDVGPAPATTLGCSGQEARNPYLFLPNQFQMAAAAAAVAVAE 604

  Fly   624 SASANGKDHVDYPSSPQFVPIGLKRE 649
            |:.|:|:..:|....   .|..:|.|
  Fly   605 SSPASGQPSLDLAHE---APPSIKSE 627

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rib	NP_001261085.1	BTB	33..133	CDD:279045	38/104 (37%)
		BTB	44..133	CDD:197585	36/93 (39%)
		HTH_psq	373..417	CDD:283007	6/54 (11%)
CG32121	NP_001097599.1	BTB	48..142	CDD:279045	34/93 (37%)
		BTB	56..149	CDD:197585	36/92 (39%)
		C2H2 Zn finger	474..494	CDD:275370	3/19 (16%)
		C2H2 Zn finger	501..518	CDD:275370	2/16 (13%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1229475at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm40394
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23110
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	4.020