DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pnr and gata3

DIOPT Version :9

Sequence 1:	NP_476685.1	Gene:	pnr / 44849	FlyBaseID:	FBgn0003117	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	NP_001004967.1	Gene:	gata3 / 448391	XenbaseID:	XB-GENE-485930	Length:	437	Species:	Xenopus tropicalis

Alignment Length:	315	Identity:	129/315 - (40%)
Similarity:	153/315 - (48%)	Gaps:	76/315 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 AASASTSASASATHVAAVKMYHSSAVAAYTDLAAAGSAAS-AGVGVGVSGYHQQAVNAPVYVPSN 97
            :.|.|||:|........|..|..|.......|.::....| :|:| |||..|......|.|
Frog   162 STSVSTSSSRHEEKECVVSKYQVSLSEPGMKLESSHPRNSMSGIG-GVSSAHHPITTYPDY---- 221

  Fly    98 RQYNHVAAHFGSAAAQNAWTTEGFGSAHAQFYSPNAAVMMGSWRSAYDPSGF-------QRSSPY 155
                                   :|   |..:.| .:::.||      |:.|       .|||.
Frog   222 -----------------------YG---AGLFQP-GSILDGS------PTHFPSKPRPKTRSST- 252

  Fly   156 ESAMDFQFGEGRECVNCGAISTPLWRRDGTGHYLCNACGLYHKMNGMNRPLIKPSKRLVSATATR 220
                     ||||||||||.||||||||||||||||||||||||||.|||||||.:||   :|.|
Frog   253 ---------EGRECVNCGATSTPLWRRDGTGHYLCNACGLYHKMNGQNRPLIKPKRRL---SAAR 305

  Fly   221 RMGLCCTNCGTRTTTLWRRNNDGEPVCNACGLYYKLHGVNRPLAMRKDGIQTRKRKPKKTGSGSA 285
            |.|..|.||.|.||||||||.:|:|||||||||||||.:||||.|:|:|||||.||.......|
Frog   306 RAGTSCANCQTTTTTLWRRNANGDPVCNACGLYYKLHNINRPLTMKKEGIQTRNRKMSSKSKKS- 369

  Fly   286 VGAGTGSGTGSTLEAIKECKEEHDLKPSLS---LERHSLSKLHTDMKSGTSSSST 337
                         :.|.:..|::....|.|   |.||..|..|....|.:|...|
Frog   370 -------------KKIHDSLEDYPKSSSFSPAALSRHMSSLSHISPFSHSSHMLT 411

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pnr	NP_476685.1	ZnF_GATA	164..212	CDD:214648	43/47 (91%)
		ZnF_GATA	168..212	CDD:238123	40/43 (93%)
		ZnF_GATA	223..270	CDD:214648	33/46 (72%)
		ZnF_GATA	226..276	CDD:238123	37/49 (76%)
gata3	NP_001004967.1	ZnF_GATA	256..306	CDD:238123	43/52 (83%)
gata3	NP_001004967.1	ZnF_GATA	310..360	CDD:238123	37/49 (76%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000130
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1745
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.030