DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pnr and gata1a

DIOPT Version :9

Sequence 1:	NP_476685.1	Gene:	pnr / 44849	FlyBaseID:	FBgn0003117	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	NP_571309.2	Gene:	gata1a / 30481	ZFINID:	ZDB-GENE-980526-268	Length:	418	Species:	Danio rerio

Alignment Length:	412	Identity:	147/412 - (35%)
Similarity:	182/412 - (44%)	Gaps:	128/412 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 DYPHFSGDYQNVTLSAASASTSASASATHVAAVKMYHSSAVAAYTDLAAAGSAA----SAGVGVG 79
            |.|.:|....::..|..|.|..:.||:::      .||.....|:..:..|:..    |||
Zfish    37 DEPFYSSSETDLLPSYYSTSVQSRASSSY------RHSPVRQVYSSQSILGNIQWLDNSAG---- 91

  Fly    80 VSGYHQQAVNAPVYVPSNRQYNH-------VAAHFGSAAAQNAWTTEGFGSAHAQFYSPN----- 132
                  .::|:| |.|::..::.       :.:|..::..||. .|..|.|....|.||:
Zfish    92 ------HSLNSP-YNPTSTVWSSSPFAKTPLHSHTSTSIYQNT-ATPSFTSPKEGFPSPSRDGKD 148

  Fly   133 ------------AAVMMGSWRS----------AYDPSG---------FQRSSPYESAMDFQFG-- 164
                        .:.|.||..|          .|.||.         ...|..|.||..:..|
Zfish   149 SPRLQEVLKAERLSPMSGSGSSFLNLSSATGGVYGPSPHMLSPYGSYMSTSQDYSSAALYSTGGP 213

  Fly   165 --------------------EGRECVNCGAISTPLWRRDGTGHYLCNACGLYHKMNGMNRPLIKP 209
                                |.||||||||.:|||||||||||||||||||||||||.|||||:|
Zfish   214 WMSPSSYSPKLRNKMRLSPPEARECVNCGATATPLWRRDGTGHYLCNACGLYHKMNGQNRPLIRP 278

  Fly   210 SKRLVSATATRRMGLCCTNCGTRTTTLWRRNNDGEPVCNACGLYYKLHGVNRPLAMRKDGIQTRK 274
            .|||:   .::|.|..|.||.|.||||||||..|||||||||||:|||.|||||.|:|||||||.
Zfish   279 KKRLI---VSKRAGTQCANCHTSTTTLWRRNASGEPVCNACGLYFKLHNVNRPLTMKKDGIQTRN 340

  Fly   275 RK---PKKTGSGSAVGAGTGSGTGSTLEAIKECK-----EEH----DLKP----SLSLERHSL-- 321
            ||   ..|.|..:|..           |...:..     :||    .|.|    |.|...|.|
Zfish   341 RKVSNRNKKGKKNAAS-----------EVYPDMSHMAPPDEHVGAYSLNPGPLLSYSHPAHLLPT 394

  Fly   322 SKLHTDMKSGTSSSSTL-MGHH 342
            |.||        ||:|| ..||
Zfish   395 STLH--------SSTTLPYTHH 408

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pnr	NP_476685.1	ZnF_GATA	164..212	CDD:214648	41/69 (59%)
		ZnF_GATA	168..212	CDD:238123	38/43 (88%)
		ZnF_GATA	223..270	CDD:214648	35/46 (76%)
		ZnF_GATA	226..276	CDD:238123	39/49 (80%)
gata1a	NP_571309.2	ZnF_GATA	237..281	CDD:238123	38/43 (88%)
gata1a	NP_571309.2	ZnF_GATA	291..342	CDD:238123	39/50 (78%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000130
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910