Protein Alignment pnr and Gata4

DIOPT Version :10

• Sequence 1: NP_476685.1
• Gene: pnr / 44849
• FlyBaseID: FBgn0003117
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: NP_001297539.1
• Gene: Gata4 / 14463
• MGIID: 95664
• Length: 442
• Species: Mus musculus
• Alignment Length: 416
• Identity: 158/416 - (37%)
• Similarity: 207/416 - (49%)
• Gaps: 78/416 - (18%)

  Fly    25 GDYQNVTLSAASASTSASASATHVAAVKMYHSSAVAAYTDLAAAGSAASAGV------GVGVS-- 81
            |.|:.....|...|..|::|..:|...::  .|:|...:.|...||||:||.      |.|.|
Mouse    16 GAYEAGGPGAFMHSAGAASSPVYVPTPRV--PSSVLGLSYLQGGGSAAAAGTTSGGSSGAGPSGA 78

  Fly    82 ---------GYHQQAVNAPVYVP---SNR-----QYNHVAAHFGSAAAQNA-------------- 115
                     |:.|.......|.|   |.|     ....:||...:|||:.|
Mouse    79 GPGTQQGSPGWSQAGAEGAAYTPPPVSPRFSFPGTTGSLAAAAAAAAAREAAAYGSGGGAAGAGL 143

  Fly   116 -----WTTEGFGSAHAQFYSPNAAVMMGSWRSAYDPSGFQRSSP-------------YESAMDF- 161
                 :...||..:::..|....|.:..||.:|...|.....||             :.:.:|.
Mouse   144 AGREQYGRPGFAGSYSSPYPAYMADVGASWAAAAAASAGPFDSPVLHSLPGRANPGRHPNLVDMF 208

  Fly   162 -QFGEGRECVNCGAISTPLWRRDGTGHYLCNACGLYHKMNGMNRPLIKPSKRLVSATATRRMGLC 225
             .|.||||||||||:||||||||||||||||||||||||||:|||||||.:||   :|:||:||.
Mouse   209 DDFSEGRECVNCGAMSTPLWRRDGTGHYLCNACGLYHKMNGINRPLIKPQRRL---SASRRVGLS 270

  Fly   226 CTNCGTRTTTLWRRNNDGEPVCNACGLYYKLHGVNRPLAMRKDGIQTRKRKPK-----KTGSGSA 285
            |.||.|.||||||||.:|||||||||||.|||||.|||||||:||||||||||     ||.:|.|
Mouse   271 CANCQTTTTTLWRRNAEGEPVCNACGLYMKLHGVPRPLAMRKEGIQTRKRKPKNLNKSKTPAGPA 335

  Fly   286 ---VGAGTGSGTGSTLEAIKECKEEHDLKPSLSLERHSLSKLHTDMKSGTSSSSTLMGH----HS 343
               :...:|:.:|::..|........:::|..:  ...||..:....|.:.:.||:.||    |.
Mouse   336 GETLPPSSGASSGNSSNATSSSSSSEEMRPIKT--EPGLSSHYGHSSSMSQTFSTVSGHGPSIHP 398

  Fly   344 AQQQQQQQQQQQQQQQQQQQQSAHQQ 369
            .....:...|.......|..|::.:|
Mouse   399 VLSALKLSPQGYASPVTQTSQASSKQ 424

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pnr	NP_476685.1	ZnF_GATA	168..212	CDD:238123	40/43 (93%)
		ZnF_GATA	226..276	CDD:238123	41/49 (84%)
Gata4	NP_001297539.1	GATA-N	1..204	CDD:461628	41/189 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	60..107		12/46 (26%)
		ZnF_GATA	216..266	CDD:238123	43/52 (83%)
		ZnF_GATA	270..321	CDD:238123	41/50 (82%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	314..393		24/80 (30%)