DRSC/TRiP Functional Genomics Resources

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Protein Alignment plu and POTEA

DIOPT Version :9

Sequence 1:NP_476683.1 Gene:plu / 44848 FlyBaseID:FBgn0003114 Length:174 Species:Drosophila melanogaster
Sequence 2:XP_024302914.1 Gene:POTEA / 340441 HGNCID:33893 Length:559 Species:Homo sapiens


Alignment Length:128 Identity:41/128 - (32%)
Similarity:66/128 - (51%) Gaps:16/128 - (12%)


- Green bases have known domain annotations that are detailed below.


  Fly     4 INALSCVGQDDVVSLRIVCTMARDGKQHNLEDVDMYGNTALLKACYLGRFECARTLLEFGANIFA 68
            |.|:.|  |:|..:|.::    :.|...||.  ||||||||..|.|......|:|||.:||:|.:
Human   137 IKAVQC--QEDECALMLL----QHGTDPNLP--DMYGNTALHYAVYNEDKLMAKTLLLYGADIES 193

  Fly    69 MNYFGQNALTLATYAGHLTLVKELLRRRSYKDFNLSSM----IPALCVATLQKHSALVAYFTQ 127
            .|..|...|.||.:.....:||.|:::::    ||:::    ..||.:|.....:::|:...|
Human   194 KNKGGLTPLLLAVHGQKQRMVKFLIKKKA----NLNALDRFGRTALILAVRCGSASIVSLLLQ 252

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
pluNP_476683.1 ANK <32..124 CDD:238125 33/95 (35%)
ANK repeat 39..70 CDD:293786 15/30 (50%)
Ank_4 40..93 CDD:290365 21/52 (40%)
POTEAXP_024302914.1 ANK 93..218 CDD:238125 33/88 (38%)
ANK repeat 100..129 CDD:293786
ANK repeat 133..162 CDD:293786 9/32 (28%)
ANK 159..283 CDD:238125 34/100 (34%)
ANK repeat 164..195 CDD:293786 15/30 (50%)
ANK repeat 197..228 CDD:293786 9/34 (26%)
ANK repeat 230..261 CDD:293786 5/23 (22%)
SMC_N <302..538 CDD:330553
CCDC144C 452..>559 CDD:317340
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
00.000

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