Protein Alignment mud and golga3

DIOPT Version :9

• Sequence 1: NP_727769.3
• Gene: mud / 44839
• FlyBaseID: FBgn0002873
• Length: 2567
• Species: Drosophila melanogaster
• Sequence 2: NP_001122017.1
• Gene: golga3 / 570879
• ZFINID: ZDB-GENE-060526-252
• Length: 1494
• Species: Danio rerio
• Alignment Length: 1740
• Identity: 372/1740 - (21%)
• Similarity: 678/1740 - (38%)
• Gaps: 464/1740 - (26%)

  Fly   152 AVVYRQGVSTSVSPCLPSSSLSPDPRSDDAPCPSTPSS----------SSSQPSSSTPQLRNHRE 206
            |:|..|.|....:|  ||::.||..|..|    |:||:          .|.:.|..:....:..:
Zfish    61 AMVEGQDVGGGSTP--PSATPSPGSRLSD----SSPSTELDPGVVSFPDSLERSEGSVHTGDALQ 119

  Fly   207 QLRLNGCEMPPPST------PKTELLEQ---RTKELRGIRTQLEVVRYEK-ALLEEQQMEKDELI 261
            .|||:   :|...|      |..|:..:   |.:..|.:..||:..|.:: .....:...|....
Zfish   120 SLRLS---IPMQETELSSTDPCVEMENEEKIRQEARRRLEEQLKQYRAQRHTERTRRSTPKSRPF 181

  Fly   262 KVLNKEKMMAKMELEKLRNVKLTEEHHDNESHHIMPYEFEHM---KGCLLKEIGL-----KESLI 318
            ..|:.|.|:....|.:...|.:|:|           |.|...   :|..|..:|:     |:|..
Zfish   182 STLDPELMLHPEGLPRANTVAMTKE-----------YSFLRTSVPRGPKLGSLGIPSSREKKSKS 235

  Fly   319 AEITDKLH---DLRVENSELSEKLNLAGKRLLEYTDRIRFLESRVDDLTRIVSSRDVMISSLESD 380
            :. :.|:|   |.:...||.|     .|............|.|.:..::.:   .::.|||..::
Zfish   236 SR-SSKIHSLADYKTPESEGS-----GGAVSASADSSFTSLHSTISSVSTV---SEISISSEANN 291

  Fly   381 KQELDKCLKEARDDLHNRIEVLNA---SSDLLDCSLSPNTTPENLASSVIDKQLREKEHENAELK 442
            ..|..:.:::...::........|   .||....|....|...|:.|:::::.......|..|:.
Zfish   292 HSESSQLIRDNISEVDGSESGFRADGNDSDSSSYSSVSTTGTYNMLSAIVNRPKAPYTVEGREIA 356

  Fly   443 EKLLNLNNSQRELCQALSS--FLQKHNIDHEFPVEWTS--SSLLSTISAIESKFVNTLEKSTQMK 503
            .:.:....|.:|:.||.:.  .:::...|.|..||..|  .|..|::| ..|..:.|.::..|:.
Zfish   357 AEAMGHFPSLQEVLQAATEERHMEELEQDREGSVEPRSRRDSFSSSVS-YGSSVMGTHDEMLQVL 420

  Fly   504 KECDVQSVCVEKLLEKCKLLSVSLGCQPKELDGFEATIPEAMESGFESSR-----------ECET 557
            ||    .:.:|..||.....:.....:..||....||:...:::..|.::           |..|
Zfish   421 KE----KMRLEGQLESLSSEASQALKEKTELQAQLATVNAQLKAQVEQTQAGQERQSTLKTEVTT 481

  Fly   558 ILSCCHM--------------KVVDIASKNNDLELDNE---RLNDKCAELKSIIDRGDQHLADIN 605
            :.|.|..              |...:||..||||:..|   ||..|..|::..::..|..::::.
Zfish   482 LRSNCSALEKAMVDLQTNLEGKNASLASLGNDLEVAEEQYQRLMVKVEEMQQSLNAKDNTVSELR 546

  Fly   606 LQLIEKEKQIKDVGAEIQELRKRNINLENMLSQIADKEASAASHAQHLKQCGELLRAKYEVCRNE 670
            .|:...:.|::.|.:|...|:          |::...:|...|..|        ||..|:   .:
Zfish   547 QQMGGLQTQLQRVQSERNALQ----------SRLKTSQAEVDSLQQ--------LRLWYQ---QQ 590

  Fly   671 LIAKNAAQDELVRMMMVPDGETLNGRVRQLIDLEMMHDEHNKMYAQMLKQLNEL-SAKHDNMTHS 734
            |   |.||:..||:    .||..|                  |.|..:.|...| :.|.:|:|.|
Zfish   591 L---NLAQEARVRL----QGEMAN------------------MQAGQMTQFGVLENLKIENVTLS 630

  Fly   735 HLDFVKRTEIELETKNAQIMAFDEHNNHFDRFLTRIFTLLRSRNCPKSTTMGSATNFLESMHIEK 799
            |    |.||.               |:...:...||...|:|......|...:
Zfish   631 H----KLTET---------------NHRSIKEKERIAVQLQSIEADMLTQEAA------------ 664

  Fly   800 RFENIEMLIEGQLLSADDLKRELDDLRSKNEELAKQNINGIIKRNKFITSLEVNTEKVKQYITDL 864
                |..:.|.:.:..:||:.:|::...:.|.|        :|.....|:||...|:||..:.
Zfish   665 ----IHQIQEAKTMVEEDLQHKLEEFEEEREHL--------LKLANTATTLERELEQVKLVLF-- 715

  Fly   865 EEEAFKRKQKVVQLENTLSKEQSNAKEMAQRLDIAQQEIKDYHVEAIRFINTIRDRLQQDFNGVN 929
                    ||..||| :|.:|                     |:|.::.:.|.::.||.....:|
Zfish   716 --------QKDSQLE-SLQRE---------------------HLELMKQLTTTQETLQTKEQALN 750

  Fly   930 TPQQLGTCMTEFLKMYDQMEVRYEESSSLVEKL-TESQAKLE-----------MQVAELQVELEN 982
                             |:|.||:|....:|:| |::.||.|           ::||......:.
Zfish   751 -----------------QLEARYQELQVQLEELQTDASAKEETLQYLQNEKIVLEVALQAARADK 798

  Fly   983 KDTNQHSGALIKQL---NDTIQNL-EKVNAKLSEDNTVSH---TVH---SKLNESLLKA------ 1031
            .:.::.:..|.:::   :||:..| ::|..|.::...:.|   |:.   .||.|..::.
Zfish   799 SELDEGAEKLGEEVLVASDTLDQLRQEVQVKATQIEALQHENGTLKKQAQKLKEQFMQQKVMVEA 863

  Fly  1032 -QKELDLRAKIIENLEASERNLSMKLCELKDLKNK-LKSSDEKIAQIKETYEEQIKALQAKCDME 1094
             :::...:.::|..|:||::.|   :.|:||||.: ||:..||.:.::|               :
Zfish   864 YRRDASSKEQLISELKASKKRL---VAEVKDLKQELLKTEGEKKSAVQE---------------Q 910

  Fly  1095 AKKNEHLERNQNQSLTQLKEDALENCVLMSTKLEELQAKLQ----EGQQLVDSQKLELDMNRKEL 1155
            |:..:.:||.|.|                   :..|:|.||    |..|| |||...|..::.:|
Zfish   911 ARLQKEVERVQQQ-------------------MNGLEAHLQSVQTERDQL-DSQLQSLQFDQNQL 955

  Fly  1156 ALV------------KSAYEAQTKLSDDLQRQKESGQQLVDNLKVELEKERKELAHVNSAIGAQT 1208
            |.|            :...||:|.:|:...:.|..|..|....|   |.:.|..|:.| |:|..:
Zfish   956 AAVTEENENLRKRVEQMQNEARTAISEQKVKMKRLGTDLTSAQK---EMKAKHKAYEN-AVGILS 1016

  Fly  1209 KLSDDLECQKESGQQLVDNLKVELEKERKELAQVKSVIEAQTKLSDDLQREKESAQ---QLVDNL 1270
            :...:....||:.:..:|.||          |||     |....|.:||.:.:|.|   |.|...
Zfish  1017 RRLQEALAAKETAEAELDKLK----------AQV-----ADGGNSQELQAKVKSLQGELQAVSQS 1066

  Fly  1271 KVELDKERKELAQVNSAFEAQTKLSDDLQRQKESAQQLVDNLKVELDKERKELAQVNSAFEAQTK 1335
            |..|:||.:|:.         |..|.:|:..:|...:|.|.   :|.:.|....::....:|..|
Zfish  1067 KAMLEKELQEVI---------TLTSTELEEYQEKVLELEDE---QLQESRNFKKRIRRLEDANKK 1119

  Fly  1336 LSDDLQREK----------ESAQQLVDNLKVELDKERKELAQVKSVIEAQTKLSDDLQRQKESAQ 1390
            |:.:|:.||          .:.::..:.|:..|.|...:|.|:...::|..|..::   :.:..:
Zfish  1120 LALELEHEKGKLSGLGKSHSALREHANILEAALAKREADLVQLNLQVQAVLKRKEE---EDQQMR 1181

  Fly  1391 QLVDNLKVELDKERKELAKVKSVIE--AQTKLSDDLQRQKESAQQLEAQTKLSDDLQRQKESAQQ 1453
            |||..|:..|:||:   .|||.:.|  |:.||.....|:...|..||. :::..|||.::|..:.
Zfish  1182 QLVQTLQTALEKEK---IKVKDLTEQVAEAKLEAAHNRRHYRAAVLEL-SEIKKDLQAKEELVKA 1242

  Fly  1454 LV----------DNLKVELDKERKELAQVKSVIE-AQTKLSDDLQRQKESAQQLVDNLKMELDKE 1507
            |.          :....|:.:.|:|||...:.:: .|.:|.|:|.:|..:.|: |::||.|::::
Zfish  1243 LEKEATTLAAQDEKHSEEVSRFREELADAHTQLQILQKQLDDELNKQPVTNQE-VEDLKWEVEQK 1306

  Fly  1508 RKELAQVKSAIGAQTKLSDDLEC---QKESVQQLVDNLKVELEKERKELAKVNSAFEAQTKLSDD 1569
            ::|:...|.    |.::.:  :|   :.:|.|.::..:|||||..::||....
Zfish  1307 QREMEAQKQ----QLEMVE--QCHQREMQSQQDMLQTIKVELEMVQEELNGTR------------ 1353

  Fly  1570 LKLQKEDAQREVFLVKERLVKEKREFEVKLATLEDIIETLEMRCTQMEEERATAYEQINKLEN-- 1632
                                |:|...:.|:..|.:.::|:..:..|::::          |:|
Zfish  1354 --------------------KDKFMLQAKVGELRNSMKTVLQQNNQLKQD----------LKNSR 1388

  Fly  1633 -RCQEKDNVKSSQLQVETFKV-EC------LHHQLKSEMATHNSLVEDLNRKLAEKVSKLDFVQS 1689
             |.|..| :|.....|...|: :|      |...||...:.:...:.:|:..|.:...::|.:|.
Zfish  1389 LRKQRMD-LKGESTPVTPVKIPDCPVPASLLDELLKPSTSVNKEPLNNLHNCLKQLKQEMDSLQK 1452

  Fly  1690 RLMTEIAEHNQVKDQLAQITDIPKVVELQ----HRLEAETAEREEAQNKL 1735
                ::.||......||...|     |||    |. .:|::.:|:.:..|
Zfish  1453 ----QMEEHTVTVTSLASPED-----ELQKLGLHD-SSESSNKEDKEEML 1492

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mud	NP_727769.3	SMC_prok_B	319..1178	CDD:274008	193/943 (20%)
		SCP-1	853..1571	CDD:114219	181/792 (23%)
		Smc	1234..>1944	CDD:224117	122/545 (22%)
		DUF948	1392..1517	CDD:295114	39/137 (28%)
golga3	NP_001122017.1	COG6	487..>580	CDD:303003	20/102 (20%)
		COG1340	770..1037	CDD:224259	67/308 (22%)
		SMC_prok_B	861..>1474	CDD:274008	171/747 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR18902
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.100