Protein Alignment mud and GCC185

DIOPT Version :9

• Sequence 1: NP_727769.3
• Gene: mud / 44839
• FlyBaseID: FBgn0002873
• Length: 2567
• Species: Drosophila melanogaster
• Sequence 2: NP_001097755.1
• Gene: GCC185 / 41459
• FlyBaseID: FBgn0037979
• Length: 1135
• Species: Drosophila melanogaster
• Alignment Length: 1409
• Identity: 299/1409 - (21%)
• Similarity: 580/1409 - (41%)
• Gaps: 401/1409 - (28%)

  Fly   253 QQMEKDELIK----VLN--KEKMMAKMELEKLRNVKLTEEHHDNESHHIMPYEFEHMKGCLLKEI 311
            :.:.|||:|.    :||  |:...||.|        ||||:|             .:|.. ||..
  Fly    17 EALSKDEIISKYKGLLNIAKKAKQAKDE--------LTEENH-------------RLKDA-LKRA 59

  Fly   312 GLKESLIAEITDKLHDLRVENSELSEKLNLAGKRLLEYTDRIRFL----ESRVDDLTRIVSSRDV 372
            ..|:|.:..:.:.:.|...:|..|:|::|...::..|..||:...    ||....|.|:....|.
  Fly    60 AEKQSSLPAMQEMVQDFTDKNLILTEEVNNLKRKTKEDADRLTQFEIENESLKRQLGRLSDENDA 124

  Fly   373 MISS---LESDKQELDKCLKEARDDLHNRIEVLNASSDLLDCSLSPNTTPENLASSVIDKQLREK 434
            ::::   :|...|:::....|.|.:|           :||:..::               :::|.
  Fly   125 LLANVDRMEKAMQQVNALGNEQRKNL-----------ELLEVDIA---------------KIKEA 163

  Fly   435 EHENAELKEKLLNLNNSQRELCQALSSFLQK--HNIDHEFPVEWTSSSLLSTISAIESKFVNTLE 497
            |.|||.|::::..:...        ||.||:  .||..      .:|......::::.:|::...
  Fly   164 EAENASLRQQVATMEEE--------SSVLQQKYQNIKE------LNSEQRKKFNSLKDRFIDVHR 214

  Fly   498 KSTQMKKECDVQSVCVEKLLEKCKLLSVSLGCQPKELDGFEATIPEAMESGFESSRECETILSCC 562
            |...: |||            ||.||...        ..:.|::.:......::|:     |.|.
  Fly   215 KLKNL-KEC------------KCVLLETQ--------HEYAASVSKWQVEIIKASQ-----LLCA 253

  Fly   563 HMKVVDIASKNNDLELDNERLNDKCAELKSIIDRGDQHLADINLQLIEKEKQIKDVGAEIQELRK 627
              |:..:.::|..|:|:|.:.::....:.:.|||  :.|    ||.:::..::..:..:.|:.::
  Fly   254 --KMASLQAENEKLKLNNGKSDNNPQTIDTGIDR--KRL----LQRVQEMDRLAKIVKQKQKNQR 310

  Fly   628 RNINLENMLSQIADKEASAASHAQHLKQCGELLRAKYEVCRNELIA--------KNAAQ------ 678
            .|:|:|.:|.:|.           .|::...:::.::.:.:.:||:        ||.|:
  Fly   311 SNLNVEYLLKKIT-----------ALEELAVIIKQQHRIDKEQLISVTKEQENTKNHARNLNVSL 364

  Fly   679 -----DELVRMMMVPDGETLNGRVRQLIDLEMMHDEHNKMYAQMLKQLNELSAKHDNMTHSHLDF 738
                 |::..::.|...|..| :.|:|.:||.:..|        |:|.||     |.:|..||..
  Fly   365 FQTKLDQMQNLVKVIAKERDN-QQRKLQELEAICIE--------LRQHNE-----DLLTRYHLKE 415

  Fly   739 VKRTEIELETKNAQIMAFDEHNNHFDRFLTRIFTLLRSRNCPKSTTMGSATNFLESMHIEKRFEN 803
            .:..|:..|.:        |.|.           .|:.|        |.|.:.|:..|
  Fly   416 QEHGELLTEMR--------ELNE-----------ALKGR--------GDAISRLQEQH------- 446

  Fly   804 IEMLIEGQLLSADDLKRELDDLRSKNEELAKQNINGIIKRNKFITSLEVNTEKVKQYITDLE--E 866
                 |.::....||:.:|    |.:::.|::.:                 :|:||..:.:|  |
  Fly   447 -----EAEVKRQRDLEAQL----SNSQQAAQEKL-----------------QKIKQLQSRVEELE 485

  Fly   867 EAFKRKQKVVQLENTLSKEQSNAKEMAQRLDIAQQEIKDYHVEAIRFINT-IRDRLQQDFNGVNT 930
            :|....|..|...:|:|:    |:|:::..::.:...:.||  .:|.|.. ::.:||:....:|.
  Fly   486 QANADAQSDVLSTSTISR----AEELSRLRELDEGYEEKYH--KLRAIAAKLKKKLQEQTQQLNE 544

  Fly   931 PQQLGTCMTEFLKMYDQMEVRYEESSSLVEKLTESQAKLEMQVAELQ-VELENKDTNQHSGALIK 994
            .:|.|.     ||         ||..::  ||.::|.:.::..|..: .:|::|:..:||..|..
  Fly   545 MEQSGA-----LK---------EELEAI--KLAQAQLQQDLNAARAENQKLKSKEKVKHSSVLNL 593

  Fly   995 QLNDTIQNLEKVNAKL----SEDNTVSHTVHSKLNESLLKAQKELDLRAKIIENLEASERNLSMK 1055
            ::....::|.:|:|||    ||...|..::.||.| ::::.:||:    .|:|..:..|...|::
  Fly   594 EIEAAEKSLSEVSAKLTAKSSELEAVKESLASKEN-TIVQLRKEI----AILEEAKNGEAAHSLE 653

  Fly  1056 LCELKDLKNKLKSSDEKIAQIKETYEEQIKALQAKCDMEAKKNEHLERNQNQSLTQLKEDALENC 1120
            |                        :|||..:|    ::.|...|   ::.|:|||.|:
  Fly   654 L------------------------KEQIDRMQ----VQVKDAVH---SKQQALTQNKD------ 681

  Fly  1121 VLMSTKLEELQAKLQEGQQLVDSQKLELDMNRKELALVKSAYEAQTKLSDDLQRQKESGQQLVDN 1185
                         |:.|   |:..|||.:..|  |.|.:||.:.::||:...|:.....|:
  Fly   682 -------------LEHG---VEQAKLEAEQLR--LQLSESAQQYESKLNTATQQLLSQTQE---- 724

  Fly  1186 LKVELEKERKELAHVNSAIGAQTKLSDDLECQKESGQQLVDNLKVELEKERKELAQVKSVI-EAQ 1249
            |::.|.::::                  ||....:.::.:::|:||. .|.|..||  ||: :.|
  Fly   725 LEMHLAEQKR------------------LETALRNAERALEDLRVEY-TEYKLKAQ--SVLRKNQ 768

  Fly  1250 TKLSDDLQREKESAQQLV------DNLKVELDKERKELAQVNSAFEAQTKLSDDLQRQKESAQQL 1308
            .|.|:   ||:|..::||      .||:...|.....|||::|..|...:.:.|||::.:....|
  Fly   769 NKGSN---REQELEEELVALRESERNLRASNDGRAARLAQLDSQIEELRQDNTDLQKRSKELVSL 830

  Fly  1309 VDNLKVELDKERKELAQVNSAFEAQTKLSDDLQREKESAQQLVDNLKVELDK-ERKELAQVKSVI 1372
            ||.|     :::.:|..:.:  :.|.:...||.::.   :|.||    |||. .:.:|.||:..:
  Fly   831 VDEL-----RQQNDLLSLEN--QRQLQFQHDLMQQH---RQQVD----ELDAGHQLQLTQVQEQL 881

  Fly  1373 EAQTKLSDDLQRQKESAQQLVDNLKVELDKERKELAKVKSVI-EAQTKLSDDLQRQKESAQQLEA 1436
            |...|:..::.:...::...||.        ..|.||:..:: :.:|.|  |......|..||.|
  Fly   882 EEAQKMQANVSQHTTASAASVDT--------SPEQAKIDYLLMDHETGL--DGHAGDVSLAQLAA 936

  Fly  1437 QTKLSDDLQRQKESAQQLVDNLKVELDKERKELAQVKSVIEAQTKLSDDLQRQKESAQQLVDNLK 1501
            |.|:|...:|..:.         :.||    ||            |:..:.:........:.|..
  Fly   937 QRKISTASRRSHDF---------MPLD----EL------------LNTSMNQITSDTVTTISNFG 976

  Fly  1502 MELDKERKELAQVKSAIGAQTKLSDDLECQKE--SVQQ-LVDNLKVELEKERKELAKVNSAFEAQ 1563
            ..:.::..|.|:: :|.|..:..|..|:..||  |:|: .|.:|...|.:..::|||:.   :..
  Fly   977 RSVSQQEDEEAEM-AARGDFSVQSAQLQATKERLSIQESRVKHLTALLAENEQDLAKLT---QMN 1037

  Fly  1564 TKLSDDLKLQKEDAQREVFLVKERLVKEKREFEVKLATLEDIIE 1607
            ..|.::|:.|:...:||..:.....:|   ...:|..||.::.|
  Fly  1038 DMLKEELRRQERSEEREQHMHNSEYLK---NVFLKFLTLNNVDE 1078

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mud	NP_727769.3	SMC_prok_B	319..1178	CDD:274008	179/894 (20%)
		SCP-1	853..1571	CDD:114219	168/737 (23%)
		Smc	1234..>1944	CDD:224117	92/386 (24%)
		DUF948	1392..1517	CDD:295114	24/125 (19%)
GCC185	NP_001097755.1	SMC_prok_B	35..813	CDD:274008	223/1068 (21%)
		TMPIT	458..>548	CDD:285135	22/116 (19%)
		GRIP	1058..1100	CDD:279767	5/24 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR18902
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100