Protein Alignment mud and Gcc2

DIOPT Version :9

• Sequence 1: NP_727769.3
• Gene: mud / 44839
• FlyBaseID: FBgn0002873
• Length: 2567
• Species: Drosophila melanogaster
• Sequence 2: XP_006256437.1
• Gene: Gcc2 / 309798
• RGDID: 1305732
• Length: 1681
• Species: Rattus norvegicus
• Alignment Length: 1916
• Identity: 425/1916 - (22%)
• Similarity: 750/1916 - (39%)
• Gaps: 525/1916 - (27%)

  Fly   217 PPSTPKTELLEQRTKE--LRGIRTQLEVVRYEKALLEEQQME------------KDELIKVLNKE 267
            |..|||:: ||...:|  ::..:.|:.:::..||...|...|            .|::||||.:.
  Rat    15 PSGTPKSK-LETLPREDLIKFAKKQMMLLQKAKARCTELDKEVEELKSKPVDGGTDDMIKVLTER 78

  Fly   268 ---KMMAKMELE------KLRNVKLTEEHHDN------------ESHHIMPYEFEHMKGCLL--- 308
               .::.|.|.|      |..|:|:.:|..|:            :||.....|.|.:|..|:
  Rat    79 LDALLLEKAETEQQCLCLKKENIKMKQEVEDSVTKLEETQKEFEQSHRNYVREMESVKNELIAVH 143

  Fly   309 ----KEIGLKESLIAEITDKLHDLRVENSELSEKLNLAGKRLLEYTDRIRFLESRVDDLTRIVSS 369
                ||   |.:|..::...:|    ..:||.|:|    |...:..|.::.|:..:.::|...
  Rat   144 SEHSKE---KAALQRDLEGAVH----RQAELLEQL----KSQSDSEDNVKKLQEEIQNITAAF-- 195

  Fly   370 RDVMISSLESDKQELDKCLKEARDDLHNRIEVLNASSDLLDCSLSPNTTPENLASSVIDKQ---- 430
                        :|...||::.          |.|:||                    :||
  Rat   196 ------------EEQTSCLQKQ----------LEATSD--------------------EKQQEII 218

  Fly   431 -LREKEHENAELKEKLLNLNNSQRELCQALSSFLQKHNIDHEFPVEWTSSSLLSTISAIESKFVN 494
             |::...:||:..:|  ::|..|.|:.|                           :.|...:.||
  Rat   219 HLQKVIEDNAQHYQK--DINTFQEEIVQ---------------------------LRATHKEEVN 254

  Fly   495 TLEKSTQMKKECDVQSVCVEKLLEKCKLLSVSLGCQPKELDGFEATIPEAMESGFESSRECETIL 559
              |..:||:.........|.||.|.    .|:| |:..|      ||||        :.:||:
  Rat   255 --ELMSQMETLAKEHEAAVNKLKEN----RVTL-CETSE------TIPE--------NYQCES-- 296

  Fly   560 SCCHMKVVDIASKNNDLELDNERLNDKCAELKSIIDRGD---QHLADINLQLIEKEKQIKDVGAE 621
                      .|.|.|.. |..:.|.||    |:..:.|   :|      .:.:|.:|::|   .
  Rat   297 ----------ESLNEDTS-DASQENQKC----SVALQEDPFAEH------TVYDKVRQLED---S 337

  Fly   622 IQELRKRNINLENMLSQIADKEASAASHAQHLKQCGELLRAKYEVCRNELIAKNAAQDELVRMMM 686
            ::||..::..|::.::.:.:.:......|||:|......|...|...|||:.....|..:|..:.
  Rat   338 LKELESQHSILKDEVTYMNNLKLKLEMDAQHIKDEFFHEREDLEFKINELLLAKEEQSYVVEKLK 402

  Fly   687 VPDGETLNGRVRQLI--------DLEMMHDEHNKMYAQ---------------MLKQLNELSAKH 728
            . :.|.||   |||.        :::.:.:.|.|..::               ::.::..|..:.
  Rat   403 Y-EREDLN---RQLCCTVEQHNKEIQRLQEHHQKEISELSETFMSGSEKEKLALMFEIQGLKEQC 463

  Fly   729 DNMTHSHLDFV------------KRTEI---------ELETKNAQIMAFDEHN---------NHF 763
            :|:.|...:.|            .:||:         |.||...| .|.|.|.         |..
  Rat   464 ENLQHEKQEVVLNYESLREMMEILQTELGESAGKISQEFETMKQQ-QASDVHELQQKLRTAFNEK 527

  Fly   764 DRFLTRIFTLLRSRNCPKSTTMGSATNFLES---MHIEKRFENIEMLIEGQLLSADDLKRELDDL 825
            |..|..|..|           .|.....|..   ..:|...:|::......|.|.......|.:|
  Rat   528 DALLETINRL-----------QGENEKLLSQELVSELESTMKNLKADNSMYLASLGQKDTLLQEL 581

  Fly   826 RSKNEELAKQNINGIIKRNKFITSLEVNTEKVKQYITDLEEEAFKRKQKV-VQLENTLSKEQSNA 889
            .:|...||::       ::.||:.::.:.|:    |.||.:: ::|:||: |:|.....:...:.
  Rat   582 EAKISSLAEE-------KDDFISKIKTSREE----IDDLHQK-WEREQKLSVELREAAEQAAQHN 634

  Fly   890 KEMAQRLDIAQQEIKDYHVEAIRFINTIRDRLQQDFNGVNTPQQLGTCMTEFLKMYDQMEVRYEE 954
            .|:.||:.....::.:          .:|::.|.|   .|...|:.| |||     ||     |.
  Rat   635 SELRQRVSELTGKLDE----------ILREKSQND---QNIMVQMKT-MTE-----DQ-----EA 675

  Fly   955 SSSLVEKLTESQAKLEMQVAELQVELENKDTNQ------HSGALIKQLNDTIQNLEKVNAKLSED 1013
            .||.::.|.|...:|..:..:|..:||...:.|      |.....|:|...::..:.:|..|..:
  Rat   676 LSSKIKSLYEENNRLHSEKVQLSRDLEALQSQQDFAYKEHVAEFEKKLQLMVEERDDLNKLLENE 740

  Fly  1014 NTVSHTVHSKLNESLLKAQKELDLRAKIIENLEASERNLSMKLCELKDLKNKLKSSDEKIAQIKE 1078
            ......|.::|.|.|.:      :|..|:|:.|.            :|:...||:..|.:..:||
  Rat   741 QLQKSFVKTQLYEFLKQ------MRPSILEDNEE------------EDVVTVLKAVGESLVTVKE 787

  Fly  1079 --------------TYEEQIKALQAKCDMEAKKNEHLERNQNQSLTQLKEDALENCVLMSTKLEE 1129
                          ..|.:||.||.:..::.::...|.|:..|....|:::..|   :.||| |.
  Rat   788 EKHNLVFEYDARVLELERRIKCLQEESVVQCEELRALVRDSEQEKILLRKELDE---VTSTK-EA 848

  Fly  1130 LQAKLQEGQQLVDSQKLELDMNRKELALVKSAYEAQT------KLSDDLQRQKE--SGQQLV--- 1183
            ||..:.|.:            |..|    |::.|.||      :||..|..:.|  :.:.||
  Rat   849 LQCDILEMK------------NTNE----KTSLENQTLSTRVEELSRSLHSKNEVHNEKDLVIEH 897

  Fly  1184 DNLKVELEKERKELAHVNSAIGAQTKLSDDLE---CQKESGQQLVDNL--KVE-LEKERKE---- 1238
            :||::.||:...||..|.:.:   ..|.|.||   ..|.....||..|  |:| ||||.|:
  Rat   898 ENLRLSLEQRESELQDVRAEL---MLLKDSLEKSPSVKNDQLSLVKELEEKIESLEKESKDKDEK 959

  Fly  1239 LAQVKSVIEAQTKLSDDLQREKESAQQLVDNLK-VELDKER-----KELAQVNSAFE----AQTK 1293
            ::::|.|   ..:...:|...::.||.|.|.|: |:.:|:|     ||..|...:::    ...|
  Rat   960 ISKIKLV---AVRAKKELDSNRKEAQTLRDELESVQSEKDRLSASMKEFIQGAESYKNLLLEYDK 1021

  Fly  1294 LSDDLQRQKESAQQLVDNLKVELDKERKELAQVNSAFEAQTKLSDDLQREKESAQQLVDNLKVEL 1358
            .|:.|..:||.|    :|.:..::...|:|......:|..|..::||....|:.|.   |.:: |
  Rat  1022 QSEQLDVEKERA----NNFEHHIEDLTKQLRDSTCQYEKLTSDNEDLLARIETLQA---NARL-L 1078

  Fly  1359 DKERKELAQVKSVIEAQTKLSDDLQRQKE-----SAQQLVDNLKVELDKERKELAKVKSVIEAQT 1418
            :.:..|:.:.|.|:|.:.: ::.||::::     |....::.|:::..||:|:|.|.
  Rat  1079 EAQILEVQRAKGVVEKELE-AEKLQKEQKIKEHVSTTNELEELQLQFQKEKKQLQKT-------- 1134

  Fly  1419 KLSDDLQRQKESAQQLEAQTKLSDDLQR-QKESAQQLVD-NLKVE-LDKERKELAQVKSVI-EAQ 1479
              ..:|:..|:.|||.........|.:| .||..|:|.: |.|:| |::|.|...|.:..: |..
  Rat  1135 --MQELELVKKDAQQTTLMNMEIADYERLMKELNQKLTNKNSKIEDLEQEMKIQKQKQETLQEEM 1197

  Fly  1480 TKLSDDLQRQKESAQQLVDNLKMELDKERKELAQVKSAIGAQTKLSDDLECQKESVQQLVDNLKV 1544
            |.|...:|..:|...|    :|..|.|.:||||..|.|......|...|:.:.|:.||.|:..|:
  Rat  1198 TSLQSSVQHYEEKNAQ----IKQLLVKTKKELADAKQAETDHLLLQASLKGELEASQQQVEVYKI 1258

  Fly  1545 ELEKERKELAKVNSAFEAQTKLSDDLKLQKEDAQREVFLVKERLV---KEKREFEVKLATLEDII 1606
            :|.:...|          :.|:.:.||...|..||.:...::|:|   :|.|..:.:.|.:....
  Rat  1259 QLAEMTSE----------KHKIHEHLKTSAEQHQRTLSAYQQRVVALQEESRTAKAEQAAVTSEF 1313

  Fly  1607 ETLEMR------------CTQMEEERATAYEQ-----INKLENRCQEKDNVKSSQLQVETFKVEC 1654
            |..::|            .:|.|.|.|....:     |::|:.:.|:..|  |.|:.|..|:.
  Rat  1314 ENYKVRVHNVLKQQKNKSVSQAETEGAKQEREHLEMLIDQLKIKLQDSQN--SLQISVSEFQT-- 1374

  Fly  1655 LHHQLKSEMATHNSLVEDLNRKLAEKVSKLDFVQSRLMTEIAEHNQVKDQLAQ------------ 1707
                |:||   |::|:|..||.|.|.|:|...::.:|.:..:|:..:|.:.||
  Rat  1375 ----LQSE---HDTLLERHNRMLQETVTKEAELREKLCSAQSENTMLKSEHAQTMCQLTSQNEAL 1432

  Fly  1708 ---ITDIPKVVELQHRLEAETAEREEAQNKLAVVTGRLDEITRELD--------------NARLE 1755
               ..|..:.::.:||...||     .|::|:.|..:|.::..|..              ..|..
  Rat  1433 RNSFRDQVRHLQDEHRKTVET-----LQHQLSKVETQLFQLKSEPPTKSPASSHQPSKSLRERRT 1492

  Fly  1756 HGAQILRMEETAREVG-NKNAELCELIEFYRNRVEALERLLLASNQELEELNS-----IQSNQAE 1814
            ....:|.|....||.| .......|.:......:::||:||.:.:.:||.|..     .:..:.|
  Rat  1493 TDLPLLDMHTVTREEGEGMETTDSESVSSAGTHIQSLEQLLSSPDSKLERLTEASLWHTEFTKEE 1557

  Fly  1815 GVRDLGDTYSAAEG-----RQTESDQDKERYQKLALDCKILQAKYRDAKDEIKRCEKKIKDQRLE 1874
            ....|..|..:|:.     |:||:..            .||..:.:..|.||:|.|:  ..:|.:
  Rat  1558 LAEKLSSTTKSADHLNGLLRETEATN------------AILMEQIKLLKSEIRRLER--NQEREK 1608

  Fly  1875 MEGKLEKMKN-KMRSLYTAEVTRMKEKQERD 1904
            ....||.:|| .:|.::      :|...||:
  Rat  1609 SVANLEYLKNVLLRFIF------LKPGSERE 1633

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mud	NP_727769.3	SMC_prok_B	319..1178	CDD:274008	191/951 (20%)
		SCP-1	853..1571	CDD:114219	190/778 (24%)
		Smc	1234..>1944	CDD:224117	178/755 (24%)
		DUF948	1392..1517	CDD:295114	38/128 (30%)
Gcc2	XP_006256437.1	SMC_prok_A	28..832	CDD:274009	201/1004 (20%)
		TMPIT	108..>205	CDD:285135	23/121 (19%)
		Smc	<464..1245	CDD:224117	212/895 (24%)
		Smc	904..1633	CDD:224117	194/803 (24%)
		Rab_bind	1545..1609	CDD:293309	15/77 (19%)
		GRIP	1611..1653	CDD:279767	8/29 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000