DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment m and nyo

DIOPT Version :9

Sequence 1:	NP_572747.1	Gene:	m / 44835	FlyBaseID:	FBgn0002577	Length:	682	Species:	Drosophila melanogaster
Sequence 2:	NP_651871.2	Gene:	nyo / 43716	FlyBaseID:	FBgn0039852	Length:	805	Species:	Drosophila melanogaster

Alignment Length:	378	Identity:	85/378 - (22%)
Similarity:	136/378 - (35%)	Gaps:	77/378 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    49 VSLEVMCGKDHMDVHLTFSHPFEGIVSSKGQHSDPRCVYVPPSTGKTFFSFRISYS--RCGTKPD 111
            ||:|  |....|...:..|..|:|.|.:||.   |:...|..:.... |.||:.|:  .|..:..
  Fly   379 VSIE--CRSGEMITKIRTSKLFDGKVYAKGA---PKSCAVNVNNSLE-FDFRMGYNDLECNVRQS 437

  Fly   112 LNGQFYENTVVVQYDKDLLEVWDEAKRLRCEWFNDYEKTASKPPMVIADLDV---------IQLD 167
            ..|: |.|.:|:|:...::...|....:.|:    |:.|..   .|:.|:|:         :..:
  Fly   438 AYGR-YMNDIVIQHHDMIVTSSDLGLAVSCQ----YDLTNK---TVLNDVDLGVTGEIESSLSEE 494

  Fly   168 FRGDNVDCWMEIQHGKGPWAPPVSGIVPLGSTLTLVVAINDYRGEFDMRVKSCVASDGSGHV-IN 231
            ...|:.:..|:|....|   ..:..:..:|..|.|...|.:....:::.|:..||.|||... |.
  Fly   495 ITIDSPNVIMKITSRDG---SDMKRMAEVGDPLALRFEIVEPNSPYEIFVRELVAMDGSDSAEIT 556

  Fly   232 LSDEFGCVLRPKMISRFLKARAPDERATVITYAFFHAFKFPDALSVHIKCKVEICRHGCLDHCQN 296
            |.|..||.....::....|  ....|..:::.  |.|||||.:..|..:..|.    .|:..|:.
  Fly   557 LIDANGCPTDQYIMGTIQK--LAQNRKVLLSQ--FDAFKFPSSEVVQFRALVT----PCIPRCEP 613

  Fly   297 TGVGGGGGGSGESLGLGLGLG---------------LTNANERKDV-------------HMSDAL 333
            .......|.|||...| :..|               |.:...|:||             .::|..
  Fly   614 VICDSEDGASGELKSL-VSYGRKKRSVLNGTDGAEFLISTRHRRDVGPVDDNILLMQSIQITDKF 677

  Fly   334 GSSSNDLLRDLALPPGGQHGMGMGMGPDHDIFYEDIIHDHKQTLGGGGMPAGG 386
            |..          |..|....|...|| |:..|..:..|....|.|.|:...|
  Fly   678 GFQ----------PEDGTTTHGNDSGP-HEKAYAGVAQDKLTCLNGYGLIMAG 719

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
m	NP_572747.1	ZP	55..286	CDD:214579	56/242 (23%)
m	NP_572747.1	Zona_pellucida	<194..287	CDD:278526	25/93 (27%)
nyo	NP_651871.2	PAN_1	121..198	CDD:278453
		PAN_AP_HGF	208..286	CDD:238532
		PAN_1	295..374	CDD:278453
		ZP	382..618	CDD:214579	59/260 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X161
	2	1.910