DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment m and mey

DIOPT Version :9

Sequence 1:	NP_572747.1	Gene:	m / 44835	FlyBaseID:	FBgn0002577	Length:	682	Species:	Drosophila melanogaster
Sequence 2:	NP_001287622.1	Gene:	mey / 43715	FlyBaseID:	FBgn0039851	Length:	774	Species:	Drosophila melanogaster

Alignment Length:	359	Identity:	76/359 - (21%)
Similarity:	133/359 - (37%)	Gaps:	62/359 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    50 SLEVMCGKDHMDVHLTFSHPFEGIVSSKGQHSDPRCVYVPPSTGKTF-FSFRISYSRCGTKPDLN 113
            ::.:.|....|...:..|..|:|.|.:||.   |:...|..:....| ...|.:...|..:....
  Fly   403 NVSIDCRSGEMITKIRTSKLFDGKVYAKGA---PKSCAVNVNNSLEFDLKMRYNDLECNVRQSAY 464

  Fly   114 GQFYENTVVVQYDKDLLEVWDEAKRLRCEWFNDYEKTASKPPMVIADLDV-------IQLDFRGD 171
            |: |.|.:|:|:...::...|....:.|:    |:.| :|..:...||.|       :..:...|
  Fly   465 GR-YMNDIVIQHHDMIVTSSDLGLAVSCQ----YDLT-NKTVVNNVDLGVTGEIESTLSEEIIVD 523

  Fly   172 NVDCWMEIQHGKGPWAPPVSGIVPLGSTLTLVVAINDYRGEFDMRVKSCVASDGSGHV-INLSDE 235
            :.:..|:|....|   ..:..|..:|..|.|...|.|....:::.|:..||.||:... |.|.|.
  Fly   524 SPNVIMKITARDG---SDMKRIAEVGDPLALRFEIVDANSPYEIFVRELVAMDGTDSAEITLIDA 585

  Fly   236 FGCVLRPKMISRFLKARAPDERATVITYAFFHAFKFPDALSVHIKCKVEICRHGCLDHCQNTGVG 300
            .||.....::|...|  ..:.|..:::.  |.|||||.:..|..:..|.    .|:..|:.....
  Fly   586 NGCPTDQYIMSAMQK--LANNRKVLLSQ--FDAFKFPSSELVQFRALVT----PCIPRCEPVICD 642

  Fly   301 GGGGGSGESL------------GL-GLGLGLTNANERKDVHMSDALGSSSNDLLRDLALPPGGQH 352
            ....|..:||            |. |:.|.:.:..:::|| ...|.|..:..|::.:.:.
  Fly   643 NDENGELKSLLSYGRRKRSVLNGTDGVELAIKSERQKRDV-SHQAAGDENILLVQSIQIT----- 701

  Fly   353 GMGMGMGPDHDIFYEDIIHDHKQTLGGGGMPAGG 386
                          :....:.....||.|..|||
  Fly   702 --------------DKFAFNGADAPGGSGSEAGG 721

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
m	NP_572747.1	ZP	55..286	CDD:214579	57/239 (24%)
m	NP_572747.1	Zona_pellucida	<194..287	CDD:278526	26/93 (28%)
mey	NP_001287622.1	PAN_1	146..223	CDD:278453
		PAN_AP_HGF	233..311	CDD:238532
		PAN_AP_HGF	319..>380	CDD:238532
		ZP	408..642	CDD:214579	59/253 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X161
	2	1.910