DRSC/TRiP Functional Genomics Resources

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Protein Alignment m and COL28A1

DIOPT Version :9

Sequence 1:NP_572747.1 Gene:m / 44835 FlyBaseID:FBgn0002577 Length:682 Species:Drosophila melanogaster
Sequence 2:NP_001032852.2 Gene:COL28A1 / 340267 HGNCID:22442 Length:1125 Species:Homo sapiens


Alignment Length:366 Identity:72/366 - (19%)
Similarity:111/366 - (30%) Gaps:125/366 - (34%)


- Green bases have known domain annotations that are detailed below.


  Fly   179 IQHGKGPWAPPVSGIVPLGSTLTLVVAINDYRGEFDMRVKSCVASDGSGH-VINLSDEFGCVLRP 242
            |.|.|.|....:|....:.....:.:|::....|..:|:   ::.|.|.. .:.|||       |
Human   163 IDHPKNPDVQSISEDARISGISFITIALSTVVNEAKLRL---ISGDSSSEPTLLLSD-------P 217

  Fly   243 KMISRFLKARAPDERATVITYAFFHAFKFPDALSV--HIKCKVEICR--------------HGCL 291
            .::.                       |..|.|.:  ..||:.:||.              ||  
Human   218 TLVD-----------------------KIQDRLDILFEKKCERKICECEKGDPGDPGPPGTHG-- 257

  Fly   292 DHCQNTGVGG--------GGGGSGESLGLGLGLGLT----NANERKDVHMSDALGSSSNDLLRDL 344
                |.|:.|        |....||:...|.| |:.    :..||.:.......|        |.
Human   258 ----NPGIKGERGPKGNPGNAQKGEAGERGPG-GIPGYKGDKGERGECGKPGIKG--------DK 309

  Fly   345 ALP----PGGQHGMGMGMGPDHDIFYEDIIHDHKQTLGGGGMPA-GGDYGHEKSVNLQPRPVHEE 404
            ..|    |.|..|:....||..|       ...|...|..|.|. .|.||...:..:..:.:..|
Human   310 GSPGPYGPKGPRGIQGITGPPGD-------PGPKGFQGNKGEPGPPGPYGSPGAPGIGQQGIKGE 367

  Fly   405 QEEADLSDLFGDEDLADLDMEG--------GE----GERYLGLK--KSGKFPHGPRQLEA----- 450
            :.:.......|...:.:....|        ||    ||.:.|.|  |..:.|.||:.|:.     
Human   368 RGQEGRPGAPGPIGVGEPGQPGPRGPEGVPGERGLPGEGFPGPKGEKGSEGPTGPQGLQGLSIKG 432

  Fly   451 ----------QKRMGVPMAGPRSLEPHGHGDEDVPRPVYRP 481
                      |..||:|..|       ..|::.:..|:..|
Human   433 EKGDIGPVGPQGPMGIPGIG-------SQGEQGIQGPIGPP 466

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
mNP_572747.1 ZP 55..286 CDD:214579 19/109 (17%)
Zona_pellucida <194..287 CDD:278526 15/95 (16%)
COL28A1NP_001032852.2 vWFA_subfamily_ECM 47..209 CDD:238727 10/48 (21%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 242..769 51/254 (20%)
Collagen 257..321 CDD:189968 17/78 (22%)
Collagen 307..403 CDD:189968 21/110 (19%)
Collagen 383..442 CDD:189968 12/58 (21%)
Collagen 501..582 CDD:189968
Collagen 581..636 CDD:189968
Collagen 713..772 CDD:189968
VWA 799..974 CDD:278519
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 999..1066
KU 1070..1123 CDD:238057
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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