DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment m and tyn

DIOPT Version :9

Sequence 1:	NP_572747.1	Gene:	m / 44835	FlyBaseID:	FBgn0002577	Length:	682	Species:	Drosophila melanogaster
Sequence 2:	NP_001027032.1	Gene:	tyn / 3354987	FlyBaseID:	FBgn0284435	Length:	715	Species:	Drosophila melanogaster

Alignment Length:	397	Identity:	75/397 - (18%)
Similarity:	134/397 - (33%)	Gaps:	120/397 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 PNIVSL----------------EVMCGKDHMDVHLTFSHPFEGIVSSKGQ---------HSDPRC 85
            ||:.:|                .|.|....:.|.:..:.||.|.:.:.|:         :||
  Fly   358 PNLTNLTRNDVNCDKTGTCYDVSVHCKDTRIAVQVRTNKPFNGRIYALGRSETCNIDVINSD--- 419

  Fly    86 VYVPPSTGKTFFSFRISYSRCGTKPDLNGQ----FYENTVVVQYDKDLLEVWDEAKRLRCEWFND 146
                        :||:..:..|  .|.|.|    .|.||||:|:...::...|:..:::|. ::.
  Fly   420 ------------AFRLDLTMAG--QDCNTQSVTGVYSNTVVLQHHSVVMTKADKIYKVKCT-YDM 469

  Fly   147 YEKTASKPPMVIADLDVIQLDFRGDNVDCWMEIQHGKGPWAPPVS-----------GIVPLGSTL 200
            ..|..:...|.|.|.::|.::               ..|.|||..           ..|.:|..|
  Fly   470 SSKNITFGMMPIRDPEMIHIN---------------SSPEAPPPRIRILDTRQREVETVRIGDRL 519

  Fly   201 TLVVAINDYRGEFDMRVKSCVASDGSGHV-INLSDEFGCVLRPKMISRFLKARAPDERATVITYA 264
            ...:.|.: ...:.:..:||||....... ..:.|:.||...|.:...|    ..|..|...||
  Fly   520 NFRIEIPE-DTPYGIFARSCVAMAKDARTSFKIIDDDGCPTDPTIFPGF----TADGNALQSTY- 578

  Fly   265 FFHAFKFPDALSVHIKCKVEICRHGCLDHCQNTGVGGGGGGSGESLGLGLGLGLTNANERKDVHM 329
              .||:|.::..|..:|.|:.|...|     ...|......|.||||         ...|:.:..
  Fly   579 --EAFRFTESYGVIFQCNVKYCLGPC-----EPAVCEWNMDSFESLG---------RRRRRSIES 627

  Fly   330 SDALGSSSNDLLRDLALPPGGQHGMGMGMGPDHDIFYEDIIHDHKQTLGGGGMPAGGDYGHEKSV 394
            :|.......::.:::.:         :..|.:...|::              .....|:..:|:|
  Fly   628 NDTKSEDDMNISQEILV---------LDFGDEKREFFK--------------ADPSTDFAKDKTV 669

  Fly   395 N-LQPRP 400
            . ::|.|
  Fly   670 TIIEPCP 676

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
m	NP_572747.1	ZP	55..286	CDD:214579	54/255 (21%)
m	NP_572747.1	Zona_pellucida	<194..287	CDD:278526	23/93 (25%)
tyn	NP_001027032.1	PAN_4	46..97	CDD:405052
		PAN_AP_HGF	131..210	CDD:238532
		PAN_1	236..327	CDD:394981
		ZP	382..598	CDD:214579	54/256 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X161
	2	1.910