DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment m and Matn4

DIOPT Version :9

Sequence 1:	NP_572747.1	Gene:	m / 44835	FlyBaseID:	FBgn0002577	Length:	682	Species:	Drosophila melanogaster
Sequence 2:	NP_001100009.1	Gene:	Matn4 / 296358	RGDID:	1309732	Length:	624	Species:	Rattus norvegicus

Alignment Length:	200	Identity:	45/200 - (22%)
Similarity:	69/200 - (34%)	Gaps:	72/200 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly   149 KTASKPPM-----VIADLDVIQ---LDFRGD--NVDCWMEIQHGKGPWAPPVSGIVPLGSTLTLV 203
            :..:.||:     ::...|:||   |.|:|.  ..|...|::||.........|        |..
  Rat   184 RAMASPPLDQHVFLVESFDLIQEFGLQFQGRLCGKDLCAELEHGCQHLCVNAPG--------TFY 240

  Fly   204 VAIND-YRGEFDMRVKSCVASD-------GSGHVINLSDEFGCVLRPKMISRFLKARA-----PD 255
            .|.|. |:...|.|  :|:|.|       |..|:        ||  ..:.|.|.:.||     .|
  Rat   241 CACNSGYKLAPDNR--NCLAIDLCAEGTHGCEHL--------CV--SSVDSYFCRCRAGFALQQD 293

  Fly   256 ERA-TVITYAFF--HAFK--------------------FPDALSVHIKCKVEICR---HGCLDHC 294
            :|: ..|.|..|  |:.:                    .||..|..::   :.|.   |||...|
  Rat   294 QRSCRAIDYCSFGNHSCQHECVSTLVGPQCRCREGHDLLPDGRSCQVR---DFCNGVDHGCEFQC 355

  Fly   295 QNTGV 299
            .:.|:
  Rat   356 VSEGL 360

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
m	NP_572747.1	ZP	55..286	CDD:214579	39/182 (21%)
m	NP_572747.1	Zona_pellucida	<194..287	CDD:278526	26/128 (20%)
Matn4	NP_001100009.1	vWA_Matrilin	33..255	CDD:238752	19/80 (24%)
		FXa_inhibition	262..297	CDD:291342	10/44 (23%)
		FXa_inhibition	303..338	CDD:291342	4/34 (12%)
		FXa_inhibition	344..379	CDD:291342	6/16 (38%)
		vWFA	385..621	CDD:294047
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X161
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000