DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment m and noah-2

DIOPT Version :9

Sequence 1:	NP_572747.1	Gene:	m / 44835	FlyBaseID:	FBgn0002577	Length:	682	Species:	Drosophila melanogaster
Sequence 2:	NP_502699.1	Gene:	noah-2 / 178365	WormBaseID:	WBGene00009926	Length:	741	Species:	Caenorhabditis elegans

Alignment Length:	292	Identity:	63/292 - (21%)
Similarity:	102/292 - (34%)	Gaps:	91/292 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    54 MCGKDHMDVHLTFSHPFEGIVSSKGQHSDPRCVYV-----------PPSTGKTFFSFRISYSRCG 107
            :|..:.:...:....|:.|.:.:..:.|  .|..|           ||.|        :| |.||
Worm   391 LCTNEGIRFIVNTKEPYTGAIYAAERFS--TCSQVVENAKQISITFPPPT--------VS-SDCG 444

  Fly   108 TKPDLNGQFYENTVVVQYD----KDLLEVWDEAKRLRCEWFND-------------YEKTA---- 151
            |.  :.....|..|||..|    ..:...||...|:.|:...|             ||.::
Worm   445 TV--IRDGKMEALVVVSLDGVLPHQVTTEWDRFYRVSCDVSMDKMVKEGSVVVTTIYEASSQNTT 507

  Fly   152 ----SKPPMVIADLDVI-QLDFRGDNVDCWMEIQHGKGPWAPPVSGIVPLGSTLTLVVAINDYRG 211
                :.||.|.|:|.:: ||:          |..|.           ..:|..|.||:. ::..|
Worm   508 VLDVATPPPVSAELQILNQLE----------EPLHK-----------ASIGDPLLLVIT-SEQAG 550

  Fly   212 EFDMRVKSCVAS--DGSGHVINLS-DEFGCVLRPKMI----SRFLKARAPDERATVITYAFFHAF 269
            ..:|.|..|.|:  .|.|..:..: .|.||...|.::    ..|.|.|...:         ..||
Worm   551 PHNMMVTECTATRVGGFGDTVPFTLIENGCPRYPALVGPVEQDFDKNRLKSD---------LRAF 606

  Fly   270 KFPDALSVHIKCKVEICR--HGC-LDHCQNTG 298
            :...:..|.|.|.:..|.  :|| :.:|.::|
Worm   607 RLDGSYDVQIVCSIMFCAGPNGCPVSNCLDSG 638

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
m	NP_572747.1	ZP	55..286	CDD:214579	58/274 (21%)
m	NP_572747.1	Zona_pellucida	<194..287	CDD:278526	23/99 (23%)
noah-2	NP_502699.1	PAN_1	28..112	CDD:278453
		PAN_AP_HGF	125..203	CDD:238532
		PAN_AP_HGF	217..292	CDD:238532
		PAN_1	310..382	CDD:278453
		ZP	392..634	CDD:214579	61/285 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910