DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment m and mua-3

DIOPT Version :9

Sequence 1:	NP_572747.1	Gene:	m / 44835	FlyBaseID:	FBgn0002577	Length:	682	Species:	Drosophila melanogaster
Sequence 2:	NP_001022674.1	Gene:	mua-3 / 176430	WormBaseID:	WBGene00003482	Length:	3767	Species:	Caenorhabditis elegans

Alignment Length:	289	Identity:	62/289 - (21%)
Similarity:	90/289 - (31%)	Gaps:	78/289 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   185 PWAPPVSGIVPLGSTLTL----VVAINDYRGEFDMRVKSCVASDGSG-----HVINLSDEFGC-- 238
            |.|...||::..|:|..:    |..::.|..|..:|:......|..|     .:...|.|:..
Worm  3500 PRAKLKSGMMASGNTAEVRNMEVARLDQYLDENAVRIPRAHLVDAHGDTSFDSLSEASSEYTIKE 3564

  Fly   239 -----VLRPKMISRFLKARAPDERA-TVITYAFFHAFKFPDALSVHIKCKVEICRHGCLDHCQNT 297
                 |:..............||:. |::|          ...:||.:              ..|
Worm  3565 EIERKVITDVTTKEIKTTTTTDEQGNTIVT----------TTEAVHPR--------------DTT 3605

  Fly   298 GVGGGGGGSGESLGLGLGLGLTNANERKDVHMSDALGSSSNDLLRDLALPPGGQHGMGMGMGPD- 361
            .|.|||....||.......|     ||.....|....|.|..:.:.::     ||....|....
Worm  3606 IVHGGGYTQNESSSSSFSGG-----ERAYQSQSQQQQSMSQGMSQSMS-----QHATSAGYSSSG 3660

  Fly   362 -----HDIFYEDIIHDHKQTLGGG----------GMPAGGD-YGHEKSVNLQPRPVHEE-QEEAD 409
                 |:..|..|.|..::..||.          ||.|... |.|..|.|   |.|.|. .||.|
Worm  3661 MESSAHNSGYASIRHTGERERGGSEEEFSIGRARGMAAASSGYQHSSSEN---REVEEYCSEEED 3722

  Fly   410 LSDLFGD------EDLADLDMEGGEGERY 432
            :....||      ::.:......||.||:
Worm  3723 VEHSVGDKRTIVTKNHSYEPFVNGESERF 3751

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
m	NP_572747.1	ZP	55..286	CDD:214579	21/117 (18%)
m	NP_572747.1	Zona_pellucida	<194..287	CDD:278526	17/109 (16%)
mua-3	NP_001022674.1	LDLa	32..60	CDD:238060
		LDLa	131..164	CDD:238060
		EGF_3	766..795	CDD:289699
		vWA_collagen_alphaI-XII-like	1229..1398	CDD:238759
		EGF_3	1662..1691	CDD:289699
		EGF_CA	1709..1755	CDD:214542
		EGF_CA	1964..1997	CDD:214542
		SEA	2873..2998	CDD:214554
		SEA	3049..3173	CDD:214554
		EGF_CA	3328..3364	CDD:214542
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910