|
Fly 7 EKRPLKRTRLGPPDIYPQDAKQREDELTPTNVKHGFTTTPPLS-DEFGTAHNSNVNASKVSAFFS 70
|.|||||.||||||:||||.||:|||||..|||.||...|.:| ||.|:|.|.|.|:||:|:.||
Zfish 11 EHRPLKRPRLGPPDVYPQDPKQKEDELTALNVKQGFNNQPAVSGDEHGSAKNVNFNSSKISSNFS 75
Fly 71 GVLAKKEELMTLPDTGRKKQQINCKDNFWPVSPRRKCTVDAWFKDLAGNKPLLSLAKRAPSFNKK 135
.::|:|....|.||||::|.|:|.|||||.|:.|.:.:::.||.||||.|||..|||:.|.|:||
Zfish 76 SIIAEKLRCNTFPDTGKRKPQVNQKDNFWLVTARSQSSINNWFTDLAGTKPLTQLAKKVPIFSKK 140
Fly 136 EEIFITLCENQVNMQRATWFIKLSAAYTLSFTESKNKKRSIYDPAAEWTGNMIKFMKELLPKLQE 200
||:|..|.:..|.:.|:.|.||::.||..:.||:|.|||.:.||..|||..:.|::.|.|.|:.|
Zfish 141 EEVFGYLAKYSVPVMRSAWMIKMTCAYHAAITENKMKKRHVIDPCIEWTQIITKYLWEQLQKVAE 205
Fly 201 YYQQNHDKSSSNGTTSGSLTAAGNGPASNGSTGTSSINSVTGSSASTNVIPVPSMASPLPPIHSP 265
:|:|: |.....||||
Zfish 206 FYRQS---------------------------------------------PSQGCGSPLP----- 220
Fly 266 ANGQQAAPGGGVNAGSVMPTTGSLGGVVGGPGSSVVGGAAGAGAAVPPGSTISGIGSQFEDSRNA 330
.||. :...|
Zfish 221 ---------------------------------------------APPA-----------EVETA 229
Fly 331 LKYWKYCHQLSKYMYEESLLDRQEFLNWILDLLDKMRTQASFDEPLKKLVLSFALQYMHDFVQSE 395
:|.|:|..:|:.:|:::.:|||.|||.|:|:..:|:|.. ::.|.:|:|...|||..:||||.
Zfish 230 MKQWEYNEKLAMFMFQDGMLDRHEFLTWVLECFEKIRPG---EDELLRLLLPLLLQYSGEFVQSA 291
Fly 396 RLCRKMAYIVSKKLAQLLNT--------------VVEQQTIKELDEPKLQ-------QDPYELAL 439
.|.|::||..:::|..||:. :..||.......|..| |.|:
Zfish 292 YLSRRLAYFCTRRLNLLLSDGSIGPGPGGHQAHGISAQQGNALPPTPTSQPAGGNQPQTPF---- 352
Fly 440 QEQMSCPHHRDIVLYLSTILQIITIECPTALVWSGIAAHRA---PSSLLGSPLDHLPLAPSVLPM 501
.:...||.||.:|..||.:||.|.:.||:|||| |.: ..:..|||||.||:|||.|||
Zfish 353 TDFYICPQHRPVVFGLSCMLQSIVLCCPSALVW-----HYSLTDSRNKTGSPLDLLPIAPSNLPM 412
Fly 502 PTRCPRTNHEIRRQLRAAESDIVLRTQHAEQRWFAAKWLSAGKNQYTS-------VLATLDHLDT 559
|......|.::|.::|..|..|..|.|..|.|| |..|.|.|: ||.||:.||.
Zfish 413 PGGNSTFNQQVRAKVREIEEQIKERGQAVEFRW------SFDKCQETTAGFTISRVLHTLEVLDN 471
Fly 560 HCFDRMEHNNSIDTLYAQIFPSPTVSRRREEDQVEPRPPYEPKQDKDTVRILCEWAVSGQRWGEH 624
|.|::.:.:||:|:||.:||.| .:.::..::.| .|...|.:|||||||.:|.|.|
Zfish 472 HSFEKSDFSNSLDSLYNRIFGS---GQSKDGHEMSP-------DDDAVVTLLCEWAVSCKRSGPH 526
Fly 625 RAMVVAILLDKRQIDVTSTPADQQSSDKDDKDSLASGAGLIDGLPVFQHVLMHFLDHDAPVLDEH 689
||||||.||:|||.::.:.... :|...|:|.|::||:.....|||||.||:.|||..||||.|
Zfish 527 RAMVVAKLLEKRQTEIEAERCG-ESEVVDEKGSVSSGSLSAATLPVFQDVLLQFLDTQAPVLTE- 589
Fly 690 VSSPQQRTEFTNLVQLFSALIRHDVFSHNAYMHTLISRGDLLLESVLVIKSGTTATKTSPPPPAP 754
..:..:|.||:|||.||..||||||||||.||.||||||||...|.| ..|..|:.
Zfish 590 PGNESERVEFSNLVLLFYELIRHDVFSHNIYMCTLISRGDLASNSHL----------PRPRSPSD 644
Fly 755 PPT-----------TTHGFDDDGFGGGLDFKHNEFDDSNVDDDLDKLVQNIKEKG--------QQ 800
.|: ::...:|.|....::..|| ..:|.|:.:.....:.:.|| |:
Zfish 645 EPSDESERKDQDAGSSVKMEDTGMSESMEIDHN--SSANFDEQMFSPPMHCESKGSPSPEKQAQE 707
Fly 801 HEAPDSPKIGPPGDGETNPGGSI----SRHYVYTKHFPIPQDDPSMSSYSSESNQRYILLFGVGK 861
.|:..:.| |...:|...: .||..|..||||||:: |.|.|.|||.::|:||||
Zfish 708 QESKSTAK-----DKGMDPAFPLVYEQPRHIQYATHFPIPQEE----SASHECNQRLVVLYGVGK 763
Fly 862 ERDEKKHAVKKMSKEIGKLFTKKFSIDVAA-AGHVKKHSRNEF--NFEATTSKCQQMAYFDQHVV 923
:|||.:||:||::|:|.|:..:|.:.:... .|..:|.|:.|. ..|...||.|.:::||||.|
Zfish 764 QRDEARHAIKKITKDILKVLNRKSTAETGGEEGQKRKRSKPEAFPTAEDIFSKFQHLSHFDQHQV 828
Fly 924 TAQCAANVLEQLNGFALGNNNYLPVQEHVAFLFDLMELALNIYSLLELCDSLLKELPEVEHQLQL 988
|:|.:.|||||:..||||.:.:||:.:|:.|:|||||.:|||..|::....||.||..||.:|.|
Zfish 829 TSQVSRNVLEQITSFALGMSYHLPLVQHIQFIFDLMEYSLNISGLIDFAIQLLNELSLVEAELLL 893
Fly 989 KKSNLVRSYTTSLALYIVSILRRYHSCLLLSPEQTLSVFEGVCRTIRHVSNPSECTSAERCIIAY 1053
|.|||..||||.|.|.||::||||||||:|:|:||..||:|:...::...||::|:||||||:||
Zfish 894 KSSNLAGSYTTGLCLCIVAVLRRYHSCLILNPDQTAQVFDGLRIVVKSGVNPADCSSAERCILAY 958
Fly 1054 LSDLHESCVLLQGK--EQSTEYYQQLQCIKRFKDIFNTPEQLDLPPQGYNPLLLQELFMAPR--- 1113
|.||:.||..|:.| |..:|: |.|....|: .::.|...| :|..::||...
Zfish 959 LYDLYTSCSHLKSKFGEIFSEF-----CSKVKNSIY-----YNIDPSDSN-MLWDQMFMIDAITN 1012
Fly 1114 -RGGKLDPHWLG----TLHESPANVYSFVSNALIAVCRE-TDNERLNDVALACAELTASCNVLSE 1172
....|:...|| .|::||||.||||.|.|:.||.: .|.||:||:.:.||||||.|..||.
Zfish 1013 PTAHNLNHSMLGKITNELNDSPANRYSFVCNVLMDVCVDHRDPERVNDIGILCAELTAYCRSLSA 1077
Fly 1173 EWIYALQSLCSGSKSPR--YPHLGGQVDIGQLKTHNALAVFVCILVARHCFSLADFVSKFALPTL 1235
||:..|::||..|.:.. :..|...||:..|..|::||.||.||:||.|..|.|.|...|:|:|
Zfish 1078 EWLGVLKALCCSSNNGNCGFNDLLCNVDVSDLSFHDSLATFVAILIARQCLLLEDLVRCVAIPSL 1142
Fly 1236 ARSVSAGGAELSVDAEAGARLTCHLVLKLFKTLEIPQPGMYSVSTSPNPLHAVGNDFS---IRLS 1297
..:..: ..|:|.||||||.::|.||:| || .:|.|.....:|.| ||.|
Zfish 1143 LNAACS-----EQDSEPGARLTCRILLHLFRT---PQ-------RNPCPQDGTKSDKSIVGIRSS 1192
Fly 1298 CDRHLLVGAHKTIPIAAVLAVLKAILIVVDNAALKTPLASGSGTSSGGLGGAFGSGKRSGFNTPV 1362
||||||..:..:|.:.||.|||||:.::.| |.|| |||.|
Zfish 1193 CDRHLLAASQNSIVVGAVFAVLKAVFMLGD-AELK-----GSGFS-------------------- 1231
Fly 1363 HPGSTPKSNEQRPADLSQILGTSDLQLGSSLTSEPEALQQPSVGG----MEQISLLEFAQAVLKQ 1423
.||.|..| |..| :||..: || :|..||:.:|:.|||.
Zfish 1232 -----------HPAGLDDI-GEDD--MGSKKS-----------GGRNVSIETASLVVYAKYVLKS 1271
Fly 1424 ICAQEHVLERCLKNAEQLCDMIIDEMLTAKQAQRVLHMICYPEPEFNIISELD--QRSMIVRILE 1486
||.||.|.|||||:..:....:.|.:|...||||:|.:||||..:.: ..|.| ||..|.|||:
Zfish 1272 ICHQEWVGERCLKSLSEDSSALQDPVLVNIQAQRLLQLICYPHRQLD-SEEGDNPQRQRIKRILQ 1335
Fly 1487 NLGQWTLRISWLDLQLMYRQSLSNNAELNVWLDTVARAAIDVFHME------------EVVLPGA 1539
|:.|||:|.|.|:||||.:|| ||| ||...|:.:|:|.|:||... ..|...:
Zfish 1336 NMDQWTMRQSSLELQLMIKQS-SNN-ELYSLLENIAKATIEVFQKSAEMNSSNPSWNGSAVSGSS 1398
Fly 1540 V---KATHKPKP--------STWLVAPLIAKLTPAVQGRILRVAGQVLESMNYFSKVSKSDCNSS 1593
| .:..|.|| ..|||||||.||..:|||.:|:.||:.||...:....|:.:.:.
Zfish 1399 VSNSNSASKLKPVLSSSERSGVWLVAPLIGKLPTSVQGHVLKAAGEELEKGQHLGPSSRKERDR- 1462
Fly 1594 GSGDEREKSNSCHSSNSYGLGGVPARNKKMPLDYQPFLGLILTCLKGQDEYKENLLVSLYAQLSQ 1658
:::||.|. |..||||.|:|||||||||.:|.||.|||:|:.|
Zfish 1463 ----QKQKSMSL-------------------LSQQPFLSLVLTCLKGQDEQREGLLTSLYSQVQQ 1504
Fly 1659 CLQSFAELDTIGGIDEPQAREEILDALQLRFSLVGGMFEAIQKNSTPTTDWAILLAQLVCQGVVD 1723
.:.::.| |... |:.:|::.:.:||:||.:||||||:.:|:::..||:||:||..::..|.||
Zfish 1505 IVTNWRE-DQYQ--DDCKAKQMMHEALKLRLNLVGGMFDTVQRSTQQTTEWAVLLLDIISSGTVD 1566
Fly 1724 LSCNRELFTTVVDMLATLVHSTLVSD-----------DERHYMNLMKKLKKEIGEKNNASIRVIR 1777
:..|.||||||:|||:.|::.||.:| ::|.||||:|||:||:|::.:.|:..:|
Zfish 1567 MQSNNELFTTVLDMLSVLINGTLAADMSSISQGSMEENKRAYMNLVKKLRKELGDRQSESLEKVR 1631
Fly 1778 QLLPLYKQPTEVIACEHSG--MDTKGNKICDIDKKQLRISDKQRISVWDILEGHKNPAPLSWVWF 1840
|||||.||..:||.||..| :|||||||...:|:.|::|.||:||.||:.||.|:.|||||.||
Zfish 1632 QLLPLPKQTRDVITCEPQGSLIDTKGNKIAGFEKEGLQVSTKQKISPWDVFEGLKHSAPLSWGWF 1696
Fly 1841 GAVKLERKPLTYEEAHRNLKYHTHSLVKPSSYYYEPLPLPPEDIEPV----PEKICIKDEMKADT 1901
|.::::||...:||..|.|.||||...|..|||..||.||.|:.||: || .:.|.||
Zfish 1697 GTIRVDRKVTKFEEQQRLLLYHTHIKPKQRSYYLAPLNLPQEEEEPLTPVPPE-----PDKKLDT 1756
Fly 1902 PSSVDQSPSAVVGGTGRGRGKGTTTRKRKPKNPKTPPVVNTQQQQPQLAQQPQQPQNVQQQQLQQ 1966
:.|::|.|:| .|:|:|.|...| :.|:..:|.|...|....
Zfish 1757 -AKVEKSVSSV------------PTKKKKKKPAST------------VKQEDYKPHNTVMQYAPG 1796
Fly 1967 QQQQQQHMQQQHMQQQQMQPNQMGQMPMNMPMNMQQFAPNPNNMMQQNAMLQQQQQQQMQQMGNN 2031
.... .|..|||..|:..|..|. |.||..||
Zfish 1797 MTPD--------------LPLSMGQTNMSYRMGYQA----PMNMYAQN----------------- 1826
Fly 2032 PMQQQLNVGGGNGQPNPQMNFMQQGPGGGGAGPQGMPGQQQQWHNAPQQQQPPQPYHNQYAPHQQ 2096
||.| |||.|..|...| ..|..:.||:| |...|
Zfish 1827 -------------QPLP--------PGGPGLEPPFRP-------RVPMNKMPPRP--NYTMP--- 1858
Fly 2097 NMQSNRIERPPLNANSKQALSQMLRQRQPFQQQAQQGPGGGFNPMQQQPQASQQQPGPQQQMNPN 2161
|||: ..:..::...:.:|. .:.||....|....:...|.::..|
Zfish 1859 NMQT-------------AGMGNLMGMEKQYQM--------NYKPMPNMAQGQMLRHQLQVRLGHN 1902
Fly 2162 -----QMRQQQMNPQQNPQSVAAFNAMQQQPQQNAQQ--------QQMNPNQQQQQQFMRGGNMR 2213
|:||...||| :::| ||.||..| ..|.|:..| .
Zfish 1903 HLIGQQIRQVTPNPQ--------YSSM--QPAQNIPQGYTSYGSHMGMQPHPSQ----------T 1947
Fly 2214 PGMAPNQMNQMNMGGQGM-----SQNPMMQQQI--PQNMVGMVNPNA---------------NQM 2256
|||.|| :.|.||. :.||.|...| .|...|.|:..| :|.
Zfish 1948 PGMVPN-----SYGNQGFQTGHPATNPTMVDSIRQMQQRPGYVHQQAPAAYGHTIQSTQRFPHQS 2007
Fly 2257 MQS-----GGAQGGNGVGVGVGVGVGGAGNNPNMGMGGMPQQGMIQQQPQQQPQQQVQFQNFQNQ 2316
||. |.||...|| .|.:||| .|.|.|.|||.|||.||| |
Zfish 2008 MQQTPMMHGLAQSHLGV----------QGIHPNM----RPNQMMEQQQQQQQQQQQ--------Q 2050
Fly 2317 YQQQQQQGMQQQGGGAGVGVGVGMAPNQQQQQQANMMGNFNPQMQQGNRNNPDFMAAAAVAQQQQ 2381
.|||||| ..||||.......|.||.|| .|.||.|
Zfish 2051 QQQQQQQ-------------------VHQQQQHIRQGPVFRPQQQQ------------QVQQQVQ 2084
Fly 2382 QQQQQQRVVPGGMMAGNRNQYMNQAPNVTMSTMMGPGPGGVVGQVPPYARQQSAGGGKPGVLNTQ 2446
||.|||:| :.|.:.| ||.|...| |
Zfish 2085 QQVQQQQV---------QQQQVQQ-------------------QVQPQQVQ-------------Q 2108
Fly 2447 QQFQQQQQQQQQLRHQMMQLQGMGGGAGGGMGAGPQQGGGAVGGGAGGGMVPQQQSMNQQQTPNL 2511
||.|||||||........|..|| ....|||......| .||:..||||..|
Zfish 2109 QQVQQQQQQQVSAAQPPAQALGM-------QALPPQQPMFQRQG--------MQQTQQQQQTAAL 2158
Fly 2512 VAQLQRQ 2518
|.|||:|
Zfish 2159 VRQLQQQ 2165
| 
