Protein Alignment g and alpha-ADR

DIOPT Version :10

• Sequence 1: NP_524785.2
• Gene: g / 44819
• FlyBaseID: FBgn0001087
• Length: 1034
• Species: Drosophila melanogaster
• Sequence 2: NP_197669.1
• Gene: alpha-ADR / 832340
• AraportID: AT5G22770
• Length: 1012
• Species: Arabidopsis thaliana
• Alignment Length: 788
• Identity: 183/788 - (23%)
• Similarity: 325/788 - (41%)
• Gaps: 164/788 - (20%)

  Fly    17 KNLTDLVRGIRN--NKDNEAKYISTCIEEIKQELRQDNISV---KCNAVAKLTYIQMLGYDISWA 76
            :.|:..:..:||  ||:.|...:...:..|:...:.:.:..   |...|.|:.||.|||||:.:.
plant     5 RGLSVFISDVRNCQNKEAERLRVDKELGNIRTCFKNEKVLTPYKKKKYVWKMLYIHMLGYDVDFG 69

  Fly    77 GFNIIEVMSSSRFTCKRIGYLAASQCFHPDSELLMLTTNMIRKDLNSQNQYDAGVALSGLSCFIS 141
            ....:.::|:.::..|::||:..|...:.:.:.|.|..|.:|.|:..:|:....:||:.:.....
plant    70 HMEAVSLISAPKYPEKQVGYIVTSCLLNENHDFLKLAINTVRNDIIGRNETFQCLALTLVGNIGG 134

  Fly   142 PDLSRDLANDIMTLM--SSTKPYLRMKAVLMMYKVFLRYPEALRPA--FPKLKEKLEDPDPGVQS 202
            .|.:..||.|:..|:  ||.:|.:|.||.|.:.::|.:.|:|:...  ..::.:.|::.|.||.:
plant   135 RDFAESLAPDVQKLLISSSCRPLVRKKAALCLLRLFRKNPDAVNVDGWADRMAQLLDERDLGVLT 199

  Fly   203 AAVNVICELARKNPKNYLPLAPIFFKLMTTSTNN---------------WMLIKIIKLFGALTPL 252
            ::.:::..|...|.:.|....|...|::.....|               |:.:|.::.......:
plant   200 SSTSLLVALVSNNHEAYSSCLPKCVKILERLARNQDVPQEYTYYGIPSPWLQVKAMRALQYFPTI 264

  Fly   253 E-PRLGKKLIEPLTNLIHSTSAM----------SLLYECINTVIAVLISISSGMPNHSASIQLCV 306
            | |...|.|.|.|..::..|..:          ::|:|.::.|:        .:......:..||
plant   265 EDPSTRKALFEVLQRILMGTDVVKNVNKNNASHAVLFEALSLVM--------HLDAEKEMMSQCV 321

  Fly   307 QKLRILIEDSDQNLKYLGLLAMSKILKTHPKS--VQAHKDLILACLDDKDESIRLRALDLLYGMV 369
            ..|...|...:.|::||||..|:::|......  ::.|:..|:..|.|.|.|||.|||||||||.
plant   322 ALLGKFISVREPNIRYLGLENMTRMLMVTDVQDIIKKHQSQIITSLKDPDISIRRRALDLLYGMC 386

  Fly   370 SKKNLMEIVKRLLGHMERAEGSAYRDELLYKVIEICAQSSYLYVTNFEWYLTVLVELIQLEAGSR 434
            ...|..:||:.||.::..||.| .|:||..|. .|.|:.   :..:..||:.|:::||     .:
plant   387 DVSNAKDIVEELLQYLSTAEFS-MREELSLKA-AILAEK---FAPDLSWYVDVILQLI-----DK 441

  Fly   435 HGRLIAEQLLDVAIRV-------PVVRQFAVNEMTNLLDTFTVSAQSNSMYEVLYAAAWIVGEFA 492
            .|..:::   |:..||       ..::.:|.::....||...:   ..:|.:|   :|:|:||:.
plant   442 AGDFVSD---DIWFRVVQFVTNNEDLQPYAASKAREYLDKIAI---HETMVKV---SAYILGEYG 497

  Fly   493 GELE-----DAEKTLNILLRPRLLPGHIQGVYVQNVIKLFARLATTCLELQDLPGLVTLCDHVLD 552
            ..|.     .|.:..:||  ...|| .|....:..::..:|:|.     :...|....|...|..
plant   498 HLLARQPGCSASELFSIL--HEKLP-TISTPTIPILLSTYAKLL-----MHAQPPDPELQKKVWA 554

  Fly   553 KLQHFNGSSDIEVQERA---------NSACM--LIEM---------------------------L 579
            ..:.:....|:|:|:||         ..|.|  |.||                           |
plant   555 VFKKYESCIDVEIQQRAVEYFELSKKGPAFMDVLAEMPKFPERQSSLIKKAENVEDTADQSAIKL 619

  Fly   580 RNQLSTSTDAMAMD-TTTEGGIPPLAIEIVQEMT--------LLF-TGELIPVAPKAQRKVPLPD 634
            |.|...|...:..| ....|..|||.:.|:...|        |.. .|.|..:.|    :.|.||
plant   620 RAQQQPSNAMVLADQQPVNGAPPPLKVPILSGSTDPESVARSLSHPNGTLSNIDP----QTPSPD 680

  Fly   635 GL-DL--DEWINAPPPEDAASSSSSEHDKDELFVSATQAGTGADGGEKRRQSLELTPEQLERQRM 696
            .| ||  ...|.|||    .:.|:.:|           ...||:|          .|::::...:
plant   681 LLSDLLGPLAIEAPP----GAVSNEQH-----------GPVGAEG----------VPDEVDGSAI 720

  Fly   697 ARLIEQSN 704
            ..:.||:|
plant   721 VPVEEQTN 728

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
g	NP_524785.2	Adaptin_N	33..578	CDD:396262	142/602 (24%)
		AP3D1	687..840	CDD:461889	4/18 (22%)
alpha-ADR	NP_197669.1	Adaptin_N	23..582	CDD:396262	139/593 (23%)
		HEAT repeat	323..347	CDD:293787	8/23 (35%)
		HEAT repeat	359..387	CDD:293787	17/27 (63%)
		HEAT repeat	397..427	CDD:293787	11/34 (32%)
		Alpha_adaptinC2	751..844	CDD:197886
		Alpha_adaptin_C	856..965	CDD:426707