Sequence 1: | NP_524785.2 | Gene: | g / 44819 | FlyBaseID: | FBgn0001087 | Length: | 1034 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_031373.2 | Gene: | AP4E1 / 23431 | HGNCID: | 573 | Length: | 1137 | Species: | Homo sapiens |
Alignment Length: | 938 | Identity: | 215/938 - (22%) |
---|---|---|---|
Similarity: | 373/938 - (39%) | Gaps: | 178/938 - (18%) |
- Green bases have known domain annotations that are detailed below.
Fly 15 FDKNLTDLVRGIR--NNKDNEAKYISTCIEEIKQELRQDNISVKC--NAVAKLTYIQMLGYDISW 75
Fly 76 AGFNIIEVMSSSRFTCKRIGYLAASQCFHPDSELLMLTTNMIRKDLNSQNQYDAGVALSGLSCFI 140
Fly 141 SPDLSRDLANDIMTLMSSTKPYLRMKAVLMMYKVFLRYPEALRPAFPKLKEKLEDPDPGVQSAAV 205
Fly 206 NVICELARKNPKNYLPLAPIFFKLMTTSTNN--------------WMLIKIIKLFGALTPLEPRL 256
Fly 257 GKKLIEPL------TNLIHSTSAMSLLYECINTVIAVLISISSGMPNHSASIQLCVQKLRILIED 315
Fly 316 SDQNLKYLGLLAMSKILKTHPKSVQAHKDLILACLDDKDESIRLRALDLLYGMVSKKNLMEIVKR 380
Fly 381 LLGHMERAEGSAYRDELLYKVIEICAQSSYLYVTNFEWYLTVLVELIQLEAGSRHG-------RL 438
Fly 439 IAEQLLDVAIRVPVVRQFAVNEMTNLLDTFTVSAQSNSMY--EVLYAAAWIVGEFAGELEDAEKT 501
Fly 502 LNILLRPRLLPGHIQGVYVQNVIKLFARLATTCLELQDLPGLVTLCDHVLDKLQH-FNGSSDIEV 565
Fly 566 QERANSACMLIEMLRNQLSTSTDAMAMDTTTEGGIPPLAIEIVQEMTLLFTGELI---------P 621
Fly 622 VAPKAQRKVPLPDGLDLDEWINAPPPEDAASSS--SSEHDKDELFVSATQAGTGADGGEKRRQSL 684
Fly 685 ELTPEQLERQRMARLIEQSNNPHYLKSTPTASGASNADQYDNIDDIPITELPLDMEGVAALRVGI 749
Fly 750 TKRSDKYLQEQQAAQGSKDGKKK---------------------------HKKGKKSKKAKNKVA 787
Fly 788 YNSSSESEGEPKPLHIVNTTLDMPEGVSMSDSEDKDGKYDPNDPHRALDIEL------------- 839
Fly 840 DITEFEAPAVRSASKKSAADKENLKTPA 867 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
g | NP_524785.2 | Adaptin_N | 33..578 | CDD:279882 | 138/576 (24%) |
HEAT repeat | 152..173 | CDD:293787 | 7/20 (35%) | ||
HEAT repeat | 185..213 | CDD:293787 | 7/27 (26%) | ||
Cnd1 | <193..266 | CDD:289487 | 16/92 (17%) | ||
HEAT repeat | 221..263 | CDD:293787 | 7/55 (13%) | ||
HEAT repeat | 272..290 | CDD:293787 | 5/17 (29%) | ||
HEAT repeat | 302..331 | CDD:293787 | 10/28 (36%) | ||
BLVR | 687..840 | CDD:283923 | 37/192 (19%) | ||
AP4E1 | NP_031373.2 | Adaptin_N | 52..596 | CDD:331138 | 138/577 (24%) |
Interaction with TEPSIN. /evidence=ECO:0000269|PubMed:26542808 | 727..1137 | 41/181 (23%) | |||
AP4E_app_platf | 1033..1132 | CDD:317244 | |||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 1 | 0.900 | - | - | E1_COG4354 | |
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 1 | 1.000 | - | - | ||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
3 | 2.810 |