| Sequence 1: | NP_524785.2 | Gene: | g / 44819 | FlyBaseID: | FBgn0001087 | Length: | 1034 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | XP_011524858.1 | Gene: | AP2A1 / 160 | HGNCID: | 561 | Length: | 994 | Species: | Homo sapiens |
| Alignment Length: | 773 | Identity: | 189/773 - (24%) |
|---|---|---|---|
| Similarity: | 341/773 - (44%) | Gaps: | 154/773 - (19%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 7 KGNFF----ERMFDKNLTDLVRGIR-----NNKDNEAKYISTCIEEIKQELRQDNI---SVKCNA 59
Fly 60 VAKLTYIQMLGYDISWAGFNIIEVMSSSRFTCKRIGYLAASQCFHPDSELLMLTTNMIRKDLNSQ 124
Fly 125 NQYDAGVALSGLSCFISPDLSRDLANDIMTLM--SSTKPYLRMKAVLMMYKVFLRYPEALRPA-- 185
Fly 186 -FPKLKEKLEDPDPGVQSAAVNVICELARKNPKNY-----LPLAPIFFKLMTTSTN--------- 235
Fly 236 --NWMLIKIIKLFGALTPLEPRLGK-KLIEPLTNLI-------------HSTSAMSLLYECINTV 284
Fly 285 IAVLISISSGMPNHSASIQLCVQKLRILIEDSDQNLKYLGLLAMSKILKTH--PKSVQAHKDLIL 347
Fly 348 ACL-DDKDESIRLRALDLLYGMVSKKNLMEIVKRLLGHMERAEGSAYRDELLYKVIEICAQSSYL 411
Fly 412 YVTNFEWYLTVLVELIQLEAGSRHGRLIAEQLLDVAIRVPVVRQFAVNEMTNLLDTFTVSAQSNS 476
Fly 477 MYEVLYAAA----------WIVGEF----AGELEDAEKTLNILLRPRLLPGHIQGVYVQNVIKLF 527
Fly 528 ARLATTCLELQDL-PGLVTLCDHVL---DKLQHFNGSSDIEVQERANSACMLIEMLRNQLSTSTD 588
Fly 589 AMAMDTTTEGGIPPLAIEIVQEMTLLFTGELIPVAPKAQRKVPLPDGLDLDEWINAPPPED---- 649
Fly 650 ---AASSSSSEHDKDELF-------VSATQAGTGADG-------GEKRRQSLELTPEQ 690 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| g | NP_524785.2 | Adaptin_N | 33..578 | CDD:279882 | 150/603 (25%) |
| HEAT repeat | 152..173 | CDD:293787 | 3/22 (14%) | ||
| HEAT repeat | 185..213 | CDD:293787 | 9/30 (30%) | ||
| Cnd1 | <193..266 | CDD:289487 | 24/89 (27%) | ||
| HEAT repeat | 221..263 | CDD:293787 | 9/53 (17%) | ||
| HEAT repeat | 272..290 | CDD:293787 | 4/17 (24%) | ||
| HEAT repeat | 302..331 | CDD:293787 | 9/28 (32%) | ||
| BLVR | 687..840 | CDD:283923 | 3/4 (75%) | ||
| AP2A1 | XP_011524858.1 | Adaptin_N | 46..608 | CDD:279882 | 152/611 (25%) |
| HEAT repeat | 349..372 | CDD:293787 | 8/23 (35%) | ||
| HEAT repeat | 386..415 | CDD:293787 | 13/28 (46%) | ||
| HEAT repeat | 425..451 | CDD:293787 | 10/27 (37%) | ||
| Alpha_adaptinC2 | 772..875 | CDD:197886 | |||
| Alpha_adaptin_C | 881..989 | CDD:280460 | |||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_COG4354 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.810 | |||||