DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment for and TPK2

DIOPT Version :9

Sequence 1:	NP_477487.1	Gene:	for / 44817	FlyBaseID:	FBgn0000721	Length:	1088	Species:	Drosophila melanogaster
Sequence 2:	NP_015121.1	Gene:	TPK2 / 855898	SGDID:	S000006124	Length:	380	Species:	Saccharomyces cerevisiae

Alignment Length:	302	Identity:	124/302 - (41%)
Similarity:	193/302 - (63%)	Gaps:	10/302 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly   774 LTDLRVIATLGVGGFGRVELVQT--NGDSSRSFALKQMKKSQIVETRQQQHIMSEKEIMGEANCQ 836
            |.|.:::.|||.|.||||.||::  ||   |.:|:|.:||.|:|:.:|.:|...|:.::......
Yeast    67 LHDFQIMRTLGTGSFGRVHLVRSVHNG---RYYAIKVLKKQQVVKMKQVEHTNDERRMLKLVEHP 128

  Fly   837 FIVKLFKTFKDKKYLYMLMESCLGGELWTILRDKGNFDDSTTRFYTACVVEAFDYLHSRNIIYRD 901
            |:::::.||:|.:.::|:|:...||||:::||....|.:...:||.|.|:.|.:|||:.||||||
Yeast   129 FLIRMWGTFQDARNIFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVILALEYLHAHNIIYRD 193

  Fly   902 LKPENLLLNERGYVKLVDFGFAKKLQTGRKTWTFCGTPEYVAPEVILNRGHDISADYWSLGVLMF 966
            |||||:||:..|::|:.||||||::||  .|||.||||:|:|||||..:.::.|.|:||||||::
Yeast   194 LKPENILLDRNGHIKITDFGFAKEVQT--VTWTLCGTPDYIAPEVITTKPYNKSVDWWSLGVLIY 256

  Fly   967 ELLTGTPPFTGSDPMRTYNIILKGIDAIEFPRNITRNASNLIKKLCRDNPAERLGYQRGGISEIQ 1031
            |:|.|..||..:.||:||..||:|  .:.:|.....:..:|:.||...:...|:|..:.|..:|:
Yeast   257 EMLAGYTPFYDTTPMKTYEKILQG--KVVYPPYFHPDVVDLLSKLITADLTRRIGNLQSGSRDIK 319

  Fly  1032 KHKWFDGFYWWGLQNCTLEPPIKPAVKS-VVDTTNFDDYPPD 1072
            .|.||....|..|....:|.|.:|.:.| :.||:.||.||.:
Yeast   320 AHPWFSEVVWERLLAKDIETPYEPPITSGIGDTSLFDQYPEE 361

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
for	NP_477487.1	DD_cGKI-alpha	385..432	CDD:213374
		Crp	518..>627	CDD:223736
		CAP_ED	520..629	CDD:237999
		Crp	632..>753	CDD:223736
		CAP_ED	638..754	CDD:237999
		S_TKc	778..1036	CDD:214567	108/259 (42%)
		STKc_cGK	783..1043	CDD:270724	110/261 (42%)
TPK2	NP_015121.1	STKc_PKA_like	69..358	CDD:270732	121/295 (41%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0616
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810