DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment for and Cnbd2

DIOPT Version :9

Sequence 1:	NP_477487.1	Gene:	for / 44817	FlyBaseID:	FBgn0000721	Length:	1088	Species:	Drosophila melanogaster
Sequence 2:	NP_081861.2	Gene:	Cnbd2 / 70873	MGIID:	1918123	Length:	673	Species:	Mus musculus

Alignment Length:	482	Identity:	96/482 - (19%)
Similarity:	171/482 - (35%)	Gaps:	147/482 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   631 DFLKSVPIFKDLAEDTLIKISDVLEETHYQRGDYIVRQGARGDTFFIISKGKVRVTIKQQDTQEE 695
            :.|:::..::...|...:.::.|:....:.|...||::|..|::|:.|..|.|.:|  :.:....
Mouse   199 NILQALDCYRSYTESLQLLLAKVIRFERFGRRRVIVKKGQMGNSFYFIYLGTVAIT--EDEDGSS 261

  Fly   696 KFI----RMLGKGDFFGEKALQGDDLRTANIICESADGVSCLVIDRETFNQLISNLDEIKHRYDD 756
            .|:    .:|.:|..|||..|....:|:|.::|  .:....||:|||.|         :.::..|
Mouse   262 AFLDPHPTLLHRGGSFGEMGLLSTTVRSATVVC--MEETEFLVVDREDF---------VANKLGD 315

  Fly   757 EGAMERRKINEEFRDINLTD-------LRVIATLGVGGFGRVELVQTNGDSSRSFALKQMKKSQI 814
            |...|.:.....||::::..       .:::|      .||:|          .|:..|
Mouse   316 EVQKETQYRYNFFRNLDIFQSWSEEKLWKLVA------LGRIE----------RFSYGQ------ 358

  Fly   815 VETRQQQHIMSEKEIMGEANCQFIVKLFKTFKDKKYLYMLMESCLGGELWTILRDKGNFDDSTTR 879
                     |..|:.|..|...||                   |.|.  ..|||.....|.|...
Mouse   359 ---------MVSKDFMNSAFITFI-------------------CQGN--CEILRLVALGDCSAYY 393

  Fly   880 FYTACVVEAFDY----LHSRNII----YRDLKPENLLLNERGYVKLVDFGFAKKLQTGRKTW--T 934
            .:....:|..|:    :|...|.    :::|:.::..|.:..|:||:      :||..|:..  .
Mouse   394 KWVWQQLELLDHKPLRIHDNEISPKERFKELQIKSYPLQDFTYLKLL------RLQKAREQQGID 452

  Fly   935 FCG--------TPEYVAPEVILNRGHDISADY--WSLGVLMFELLTGTPPFTGSDPMRTYNIILK 989
            |.|        .|:.:.|::....||.:....  ...|.|..|.:.|           .|..|.|
Mouse   453 FHGKINKVENTLPKLLGPKIKSRFGHLVKCSMVNTKFGELPKEAIVG-----------VYMKIHK 506

  Fly   990 -------GIDAIEFPRNITRNASNLIKKLCRDNPAERLGYQRGGISEIQKHKWFDGFYWWGLQNC 1047
                   |:.....|.         |::.||......||.:   :.:::|.|::|     .:...
Mouse   507 TEEGEIVGLHQAFVPE---------IQRDCRPFILLSLGSE---LIQVRKEKFYD-----MVDEE 554

  Fly  1048 TLEPPIKPAVKSVVDTTNFDDYPPDPE 1074
            |....||..|          |||.|.:
Mouse   555 TRAKIIKMDV----------DYPSDED 571

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
for	NP_477487.1	DD_cGKI-alpha	385..432	CDD:213374
		Crp	518..>627	CDD:223736
		CAP_ED	520..629	CDD:237999
		Crp	632..>753	CDD:223736	29/124 (23%)
		CAP_ED	638..754	CDD:237999	28/119 (24%)
		S_TKc	778..1036	CDD:214567	53/284 (19%)
		STKc_cGK	783..1043	CDD:270724	53/286 (19%)
Cnbd2	NP_081861.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..89
		Crp	200..>353	CDD:223736	38/181 (21%)
		CAP_ED	211..308	CDD:237999	27/100 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0664
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810