DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment for and prkx

DIOPT Version :9

Sequence 1:	NP_477487.1	Gene:	for / 44817	FlyBaseID:	FBgn0000721	Length:	1088	Species:	Drosophila melanogaster
Sequence 2:	XP_690430.2	Gene:	prkx / 561941	ZFINID:	ZDB-GENE-090313-408	Length:	357	Species:	Danio rerio

Alignment Length:	321	Identity:	152/321 - (47%)
Similarity:	204/321 - (63%)	Gaps:	21/321 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   770 RDINLTDLRVIATLGVGGFGRVELV---QTNGDSSRSFALKQMKKSQIVETRQQQHIMSEKEIMG 831
            |...|.||..|||:|.|.||||.||   :|.|    .||||.||...::..:|:||:.:|||::.
Zfish    41 RTYTLDDLDTIATVGTGTFGRVFLVKDKKTRG----FFALKAMKIPDVIRLKQEQHVHNEKEVLT 101

  Fly   832 EANCQFIVKLFKTFKDKKYLYMLMESCLGGELWTILRDKGNFDDSTTRFYTACVVEAFDYLHSRN 896
            |.|..|:|:||.|..|.::||||||...||||::.||.:|:|.:||..||:|.:|.|.:||||:.
Zfish   102 EVNHPFLVRLFWTHHDDRFLYMLMEYVNGGELFSYLRSRGHFSNSTGMFYSAEIVCAIEYLHSKE 166

  Fly   897 IIYRDLKPENLLLNERGYVKLVDFGFAKKLQTGRKTWTFCGTPEYVAPEVILNRGHDISADYWSL 961
            |:||||||||:||:..|:::|.||||||||  ..:|||.||||||:|||||.::||..:.|:|:|
Zfish   167 IVYRDLKPENILLDSEGHIRLTDFGFAKKL--SERTWTLCGTPEYLAPEVIQSKGHGRAVDWWAL 229

  Fly   962 GVLMFELLTGTPPFTGSDPMRTYNIILKGIDAIEFPRNITRNASNLIKKLCRDNPAERLGYQRGG 1026
            |||:||:|.|.|||...:|...|..||.|  .:||||::.....:||||....:...|||..:.|
Zfish   230 GVLIFEMLAGYPPFFDDNPFGIYQKILAG--KLEFPRHLDLYVKDLIKKFLVTDRERRLGNMKNG 292

  Fly  1027 ISEIQKHKWFDGFYWWGLQNCTLEPPIKPAVKSVVDTTNFDDYPPDPEGPPPDDVTGWDKD 1087
            ..:::||:||....|..:....|:|||.|.|....||:|||.| ||.|         |.||
Zfish   293 ADDVKKHRWFKSVNWESVPCRKLKPPIVPKVSHEGDTSNFDSY-PDEE---------WKKD 343

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
for	NP_477487.1	DD_cGKI-alpha	385..432	CDD:213374
		Crp	518..>627	CDD:223736
		CAP_ED	520..629	CDD:237999
		Crp	632..>753	CDD:223736
		CAP_ED	638..754	CDD:237999
		S_TKc	778..1036	CDD:214567	127/260 (49%)
		STKc_cGK	783..1043	CDD:270724	127/262 (48%)
prkx	XP_690430.2	PTZ00263	43..357	CDD:140289	151/319 (47%)
prkx	XP_690430.2	STKc_PRKX_like	46..337	CDD:270763	144/299 (48%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0616
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810