DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment for and LOC556339

DIOPT Version :9

Sequence 1:	NP_477487.1	Gene:	for / 44817	FlyBaseID:	FBgn0000721	Length:	1088	Species:	Drosophila melanogaster
Sequence 2:	XP_021328301.1	Gene:	LOC556339 / 556339	-ID:	-	Length:	771	Species:	Danio rerio

Alignment Length:	747	Identity:	337/747 - (45%)
Similarity:	474/747 - (63%)	Gaps:	86/747 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   395 IQAKELKIQEMQRALQFKDNEIAELKSHLDKFQSVFPFSRGSAAGCAGTGGASGSGAGGSGGSGP 459
            ::|:|.::|.:||.|:.|       .|.:||.|...                   |....|.|.|
Zfish    58 LRAQENQLQSLQRELEAK-------VSQIDKLQDAI-------------------GYNSLGRSPP 96

  Fly   460 GTATGATR------KSGQNFQR-----QRAL----GISAEPQS----------ESSLLLEHVSFP 499
            .....:.|      :....|.|     .|.|    |:||||.:          .||...:|:.
Zfish    97 APLRHSRRLLSVINQGSMRFHRVAVEVHRRLKAKEGVSAEPTTRHFCHDHRAHRSSTERQHIR-- 159

  Fly   500 KYDKDERSRELIKAAILDNDFMKNLDLTQIREIVDCMYPVKYPAKNLIIKEGDVGSIVYVMEDGR 564
               ||..:::||..|::.|||:|.|:....||:|||||...|.|:.|:|:||:.|:.:||:.:|.
Zfish   160 ---KDSGTKKLINEALMKNDFLKKLEPQHTREMVDCMYEKIYGAEQLVIQEGEPGNFLYVLAEGL 221

  Fly   565 VEVSREGKYLSTLSGAKVLGELAILYNCQRTATITAITECNLWAIERQCFQTIMMRTGLIRQAEY 629
            :||.:.||:|..:......|||||||||:||||:.|:::.::||::||.|||||||:...|..||
Zfish   222 LEVIQNGKFLGQMRPGTAFGELAILYNCKRTATVKAVSQSHIWALDRQTFQTIMMRSTQARHEEY 286

  Fly   630 SDFLKSVPIFKDLAEDTLIKISDVLEETHYQRGDYIVRQGARGDTFFIISKGKVRVTIKQQDTQE 694
            ..||:||.:.|||.|:.|.||.|.||..::.:|:||:|:|..|:|||||:||:|.||...:...|
Zfish   287 FSFLRSVSLLKDLPEEKLAKIIDCLEIDYFDKGEYIIREGEEGNTFFIIAKGEVSVTQTTEGFTE 351

  Fly   695 EKFIRMLGKGDFFGEKALQGDDLRTANIICESADGVSCLVIDRETFNQLISNLDEIK---HRYDD 756
            .:.|:.|..||:||||||..:|:|:||||.:..| ..|||:||:.||:::...:|::   ..|.:
Zfish   352 PQEIKTLRVGDYFGEKALISEDVRSANIIAKEND-TQCLVVDRDNFNEMVGTYEELQAYLREYVE 415

  Fly   757 E---------------------GAMERRKINEEFRDIN----LTDLRVIATLGVGGFGRVELVQT 796
            |                     .|.|.|::.|:...::    |.:|:|:||||:|||||||||:.
Zfish   416 ELSLSDERRNAVPQSPLYERSPEAAELRRLKEKATALSSTSFLKELQVVATLGMGGFGRVELVKL 480

  Fly   797 NGDSSRSFALKQMKKSQIVETRQQQHIMSEKEIMGEANCQFIVKLFKTFKDKKYLYMLMESCLGG 861
            ......:||||.:||..||:||||:||.|||.|:.:.|..|||:||:||:|.|::|||:|.||||
Zfish   481 KDSEDTAFALKCIKKKHIVDTRQQEHIYSEKIILQQTNSNFIVRLFRTFRDDKFVYMLLEVCLGG 545

  Fly   862 ELWTILRDKGNFDDSTTRFYTACVVEAFDYLHSRNIIYRDLKPENLLLNERGYVKLVDFGFAKKL 926
            |||::|||...||:.|.||.|.||:|||||||.:.|:|||||||||||:..||||:.|||||||:
Zfish   546 ELWSLLRDMSCFDEPTARFCTGCVLEAFDYLHGKGIVYRDLKPENLLLDAEGYVKMADFGFAKKI 610

  Fly   927 QTGRKTWTFCGTPEYVAPEVILNRGHDISADYWSLGVLMFELLTGTPPFTGSDPMRTYNIILKGI 991
            ..|:|||||||||||||||||:|:|||..||.||||:|:||||.|:||||||||:|.|.::|.||
Zfish   611 GLGKKTWTFCGTPEYVAPEVIMNKGHDFGADCWSLGILIFELLIGSPPFTGSDPIRIYTMVLHGI 675

  Fly   992 DAIEFPRNITRNASNLIKKLCRDNPAERLGYQRGGISEIQKHKWFDGFYWWGLQNCTLEPPIKPA 1056
            :.::.|:.|::...:||::||:.|||||||.::.||.:|:|||||.||.|.||:...|..|::..
Zfish   676 EKVDIPKRISKRPEDLIRRLCKLNPAERLGNKKNGIIDIKKHKWFQGFNWEGLRRRKLMSPLRRE 740

  Fly  1057 VKSVVDTTNFDDYPPDPEGPPPDDVTGWDKDF 1088
            :|..:|.:.||.:||:.| .|||:.:||||||
Zfish   741 LKGPLDHSYFDMFPPELE-EPPDEFSGWDKDF 771

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
for	NP_477487.1	DD_cGKI-alpha	385..432	CDD:213374	11/36 (31%)
		Crp	518..>627	CDD:223736	53/108 (49%)
		CAP_ED	520..629	CDD:237999	51/108 (47%)
		Crp	632..>753	CDD:223736	56/123 (46%)
		CAP_ED	638..754	CDD:237999	52/118 (44%)
		S_TKc	778..1036	CDD:214567	160/257 (62%)
		STKc_cGK	783..1043	CDD:270724	162/259 (63%)
LOC556339	XP_021328301.1	CAP_ED	177..286	CDD:237999	51/108 (47%)
		CAP_ED	295..410	CDD:237999	52/115 (45%)
		STKc_cGK	467..727	CDD:270724	162/259 (63%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D123183at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920