DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment for and Pka-C2

DIOPT Version :9

Sequence 1:	NP_477487.1	Gene:	for / 44817	FlyBaseID:	FBgn0000721	Length:	1088	Species:	Drosophila melanogaster
Sequence 2:	NP_733397.2	Gene:	Pka-C2 / 43644	FlyBaseID:	FBgn0000274	Length:	354	Species:	Drosophila melanogaster

Alignment Length:	336	Identity:	113/336 - (33%)
Similarity:	187/336 - (55%)	Gaps:	17/336 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly   737 RETFNQLISNLD-EIKHRYDDEGAMERRKINEEFRDINLTDLRVIATLGVGGFGRVELVQTNGDS 800
            :|.:|.::.|:. |.:.|::.:         .:....||.:....|.||.|.||.|.||:.. ..
  Fly    13 KEDYNVILDNMSREFEERWNHQ---------TQSPYTNLENYITRAVLGNGSFGTVMLVREK-SG 67

  Fly   801 SRSFALKQMKKSQIVETRQQQHIMSEKEIMGEANCQFIVKLFKTFKDKKYLYMLMESCLGGELWT 865
            ...:|.|.|.|..:|..:|..|:.:||.::..|...|::.|..:.|...|||:::....||||::
  Fly    68 KNYYAAKMMSKEDLVRLKQVAHVHNEKHVLNAARFPFLIYLVDSTKCFDYLYLILPLVNGGELFS 132

  Fly   866 ILRDKGNFDDSTTRFYTACVVEAFDYLHSRNIIYRDLKPENLLLNERGYVKLVDFGFAKKLQTGR 930
            ..|....|::...|||.|.|..|.:|:|..:::||||||||:||::|||:|:.||||.|::. ||
  Fly   133 YHRRVRKFNEKHARFYAAQVALALEYMHKMHLMYRDLKPENILLDQRGYIKITDFGFTKRVD-GR 196

  Fly   931 KTWTFCGTPEYVAPEVILNRGHDISADYWSLGVLMFELLTGTPPFT--GSDPMRTYNIILKGIDA 993
             |.|.||||||:|||::..|.::.|.|:|:.|:|::|.:.|..||.  ..|.:..|:.|.  |..
  Fly   197 -TSTLCGTPEYLAPEIVQLRPYNKSVDWWAFGILVYEFVAGRSPFAIHNRDVILMYSKIC--ICD 258

  Fly   994 IEFPRNITRNASNLIKKLCRDNPAERLGYQRGGISEIQKHKWFDGFYWWGLQNCTLEPPIKPAVK 1058
            .:.|...|....:|::.|.:.:.::|||....|.|:::.|.||.|..|:|:.|..:..|.:|.:.
  Fly   259 YKMPSYFTSQLRSLVESLMQVDTSKRLGNSNDGSSDVKSHPWFQGVDWFGILNQEVTAPYQPTIS 323

  Fly  1059 SVVDTTNFDDY 1069
            ...|.:||:::
  Fly   324 GAEDLSNFENF 334

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
for	NP_477487.1	DD_cGKI-alpha	385..432	CDD:213374
		Crp	518..>627	CDD:223736
		CAP_ED	520..629	CDD:237999
		Crp	632..>753	CDD:223736	4/16 (25%)
		CAP_ED	638..754	CDD:237999	4/17 (24%)
		S_TKc	778..1036	CDD:214567	95/259 (37%)
		STKc_cGK	783..1043	CDD:270724	98/261 (38%)
Pka-C2	NP_733397.2	PKc_like	43..334	CDD:328722	106/295 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0616
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24353
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.910