DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment for and CG12069

DIOPT Version :9

Sequence 1:	NP_477487.1	Gene:	for / 44817	FlyBaseID:	FBgn0000721	Length:	1088	Species:	Drosophila melanogaster
Sequence 2:	NP_651819.1	Gene:	CG12069 / 43643	FlyBaseID:	FBgn0039796	Length:	356	Species:	Drosophila melanogaster

Alignment Length:	345	Identity:	123/345 - (35%)
Similarity:	187/345 - (54%)	Gaps:	28/345 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   733 LVID--RETFNQLISNLDEIKHRYDDEGAMERRKINEEFRDINLTDLRVIATLGVGGFGRVELVQ 795
            |::|  ||.||:..:.                   |.......|.|..:.||||.|.||:|:||:
  Fly    20 LILDKLREDFNKKFAT-------------------NTPSPSTGLDDYEIKATLGSGSFGKVQLVR 65

  Fly   796 TNGDSSRSFALKQMKKSQIVETRQQQHIMSEKEIMGEANCQFIVKLFKTFKDKKYLYMLMESCLG 860
            .. :|...:|.||:.|.|||:|:|..|:||||.::........|.|..::||...||:::....|
  Fly    66 ER-ESGVYYASKQLSKDQIVKTKQVSHVMSEKNVLRSMTFPNTVNLIASYKDFDSLYLVLPLIGG 129

  Fly   861 GELWTILRDKGNFDDSTTRFYTACVVEAFDYLHSRNIIYRDLKPENLLLNERGYVKLVDFGFAKK 925
            |||:|..|....|.:...|||.|.|..|.:|||..:::||||||||:::::.||:|:.|||||||
  Fly   130 GELFTYHRKVRKFTEKQARFYAAQVFLALEYLHHCSLLYRDLKPENIMMDKNGYLKVTDFGFAKK 194

  Fly   926 LQTGRKTWTFCGTPEYVAPEVILNRGHDISADYWSLGVLMFELLTGTPPFT--GSDPMRTYNIIL 988
            ::|  :|.|.||||||:.||:|.::.:..|.|:|:.|||:||.:.|..||:  ..|.|..||.|.
  Fly   195 VET--RTMTLCGTPEYLPPEIIQSKPYGTSVDWWAFGVLVFEFVAGHSPFSAHNRDVMSMYNKIC 257

  Fly   989 KGIDAIEFPRNITRNASNLIKKLCRDNPAERLGYQRGGISEIQKHKWFDGFYWWGLQNCTLEPPI 1053
            :.  ..:.|...:....:|:..|.:.:.::|.|....|..:|::|:||....|..|.|.|:..|.
  Fly   258 EA--DYKMPSYFSGALRHLVDHLLQVDLSKRFGNLINGNRDIKEHEWFKDVEWIPLLNQTVNAPY 320

  Fly  1054 KPAVKSVVDTTNFDDYPPDP 1073
            .|.:.:..|.:|||.....|
  Fly   321 VPNISNPEDISNFDKVSDKP 340

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
for	NP_477487.1	DD_cGKI-alpha	385..432	CDD:213374
		Crp	518..>627	CDD:223736
		CAP_ED	520..629	CDD:237999
		Crp	632..>753	CDD:223736	6/21 (29%)
		CAP_ED	638..754	CDD:237999	6/22 (27%)
		S_TKc	778..1036	CDD:214567	101/259 (39%)
		STKc_cGK	783..1043	CDD:270724	102/261 (39%)
CG12069	NP_651819.1	PTZ00263	44..356	CDD:140289	116/302 (38%)
CG12069	NP_651819.1	PKc_like	45..335	CDD:304357	113/294 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0616
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24353
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.910