Protein Alignment for and Prkcb

DIOPT Version :10

• Sequence 1: NP_477487.1
• Gene: for / 44817
• FlyBaseID: FBgn0000721
• Length: 1088
• Species: Drosophila melanogaster
• Sequence 2: NP_036845.3
• Gene: Prkcb / 25023
• RGDID: 3396
• Length: 673
• Species: Rattus norvegicus
• Alignment Length: 434
• Identity: 124/434 - (28%)
• Similarity: 207/434 - (47%)
• Gaps: 58/434 - (13%)

  Fly   684 RVTIKQQDTQEEKFIR-----MLGKGDFFGEKALQGDDLRTANIICESADGVSCLVI--DRETFN 741
            |..:|:.|......:.     :..:.||.|..:....:|:.|.:     ||...|:.  :.|.||
  Rat   228 RFQLKESDKDRRLSVEIWDWDLTSRNDFMGSLSFGISELQKAGV-----DGWFKLLSQEEGEYFN 287

  Fly   742 QLI-----SNLDEIKHRYDDEGAMERRKI-------------------NEEFRD-INLTDLRVIA 781
            ..:     ...:|::.::      ||.||                   |...|| :.|||...:.
  Rat   288 VPVPPEGSEGNEELRQKF------ERAKIGQGTKAPEEKTANTISKFDNNGNRDRMKLTDFNFLM 346

  Fly   782 TLGVGGFGRVELVQTNGDSSRSFALKQMKKSQIVETRQQQHIMSEKEIMG-EANCQFIVKLFKTF 845
            .||.|.||:|.|.:..| :...:|:|.:||..:::....:..|.||.::. .....|:.:|...|
  Rat   347 VLGKGSFGKVMLSERKG-TDELYAVKILKKDVVIQDDDVECTMVEKRVLALPGKPPFLTQLHSCF 410

  Fly   846 KDKKYLYMLMESCLGGELWTILRDKGNFDDSTTRFYTACVVEAFDYLHSRNIIYRDLKPENLLLN 910
            :....||.:||...||:|...::..|.|.:....||.|.:.....:|.|:.|||||||.:|::|:
  Rat   411 QTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSKGIIYRDLKLDNVMLD 475

  Fly   911 ERGYVKLVDFGFAKK-LQTGRKTWTFCGTPEYVAPEVILNRGHDISADYWSLGVLMFELLTGTPP 974
            ..|::|:.|||..|: :..|..|.||||||:|:|||:|..:.:..|.|:|:.|||::|:|.|..|
  Rat   476 SEGHIKIADFGMCKENIWDGVTTKTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAP 540

  Fly   975 FTGSDPMRTYNIILKGIDAIEFPRNITRNASNLIKKLCRDNPAERLGYQRGGISEIQKHKWFDGF 1039
            |.|.|....:..|::  ..:.:|:::::.|..:.|.|...:|.:|||....|..:|::|.:|...
  Rat   541 FEGEDEDELFQSIME--HNVAYPKSMSKEAVAICKGLMTKHPGKRLGCGPEGERDIKEHAFFRYI 603

  Fly  1040 YWWGLQNCTLEPPIKPAVKSVVDTTNFDDY---------PPDPE 1074
            .|..|:...::||.||.... .:..|||.:         |||.|
  Rat   604 DWEKLERKEIQPPYKPKACG-RNAENFDRFFTRHPPVLTPPDQE 646

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
for	NP_477487.1	DD_cGKI-alpha	385..432	CDD:213374
		CAP_ED	520..629	CDD:237999
		CAP_ED	638..754	CDD:237999	15/81 (19%)
		STKc_cGK	783..1043	CDD:270724	87/261 (33%)
Prkcb	NP_036845.3	C1_cPKC_rpt1	35..92	CDD:410383
		C1_cPKC_rpt2	102..155	CDD:410386
		C2_PKC_alpha_gamma	159..289	CDD:175992	14/65 (22%)
		STKc_cPKC_beta	341..663	CDD:270767	100/310 (32%)