DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment for and F47F2.1

DIOPT Version :9

Sequence 1:	NP_477487.1	Gene:	for / 44817	FlyBaseID:	FBgn0000721	Length:	1088	Species:	Drosophila melanogaster
Sequence 2:	NP_508671.2	Gene:	F47F2.1 / 180673	WormBaseID:	WBGene00018569	Length:	398	Species:	Caenorhabditis elegans

Alignment Length:	366	Identity:	136/366 - (37%)
Similarity:	211/366 - (57%)	Gaps:	29/366 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   725 ESADGVSCLVIDRE-----TF--------NQLISNLDEIKHRYDDEGAMERRKINEEFRDINLTD 776
            ||.:..||   ..|     ||        |..::.|.|..|.        :..|.......:|:.
Worm    36 ESVEDESC---SNECSASFTFDTNNNSRGNNQVNELAEETHM--------KLSITPTRESFSLSQ 89

  Fly   777 LRVIATLGVGGFGRVELVQTNGDSSRSFALKQMKKSQIVETRQQQHIMSEKEIMGEANCQFIVKL 841
            |..|.|:|.|.||||||.: :..:...:|||.:...::|:.||.||:.:||.::.:....||||:
Worm    90 LERIITIGKGTFGRVELAR-DKITGAHYALKVLNIRRVVDMRQTQHVHNEKRVLLQLKHPFIVKM 153

  Fly   842 FKTFKDKKYLYMLMESCLGGELWTILRDKGNFDDSTTRFYTACVVEAFDYLHSRNIIYRDLKPEN 906
            :.:.||..:|||:||...|||:::.||...:|.:|..|||.:.:|.|.:|:||..|:||||||||
Worm   154 YASEKDSNHLYMIMEFVPGGEMFSYLRASRSFSNSMARFYASEIVCALEYIHSLGIVYRDLKPEN 218

  Fly   907 LLLNERGYVKLVDFGFAKKLQTGRKTWTFCGTPEYVAPEVILNRGHDISADYWSLGVLMFELLTG 971
            |:|::.|::|:.||||||:|:.  :|:|.||||:|:|||.:...||:...|:|:||:|::|::.|
Worm   219 LMLSKEGHIKMADFGFAKELRD--RTYTICGTPDYLAPESLARTGHNKGVDWWALGILIYEMMVG 281

  Fly   972 TPPFTGSDPMRTYNIILKGIDAIEFPRNITRNASNLIKKLCRDNPAERLGYQRGGISEIQKHKWF 1036
            .|||.|......|:.|::  ..::|||:....|.:|:|||...:..:|:|..:.|..:::.||||
Worm   282 KPPFRGKTTSEIYDAIIE--HKLKFPRSFNLAAKDLVKKLLEVDRTQRIGCMKNGTQDVKDHKWF 344

  Fly  1037 DGFYWWGLQNCTLEPPIKPAVKSVVDTTNFDDYPPDPEGPP 1077
            :...|....:..:||||.|.:....||.|||||..|..|.|
Worm   345 EKVNWDDTLHLRVEPPIVPTLYHPGDTGNFDDYEEDTTGGP 385

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
for	NP_477487.1	DD_cGKI-alpha	385..432	CDD:213374
		Crp	518..>627	CDD:223736
		CAP_ED	520..629	CDD:237999
		Crp	632..>753	CDD:223736	10/40 (25%)
		CAP_ED	638..754	CDD:237999	11/41 (27%)
		S_TKc	778..1036	CDD:214567	104/257 (40%)
		STKc_cGK	783..1043	CDD:270724	105/259 (41%)
F47F2.1	NP_508671.2	PTZ00263	80..379	CDD:140289	121/303 (40%)
F47F2.1	NP_508671.2	PKc_like	88..379	CDD:304357	120/295 (41%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910