Protein Alignment for and CNBD2

DIOPT Version :9

• Sequence 1: NP_477487.1
• Gene: for / 44817
• FlyBaseID: FBgn0000721
• Length: 1088
• Species: Drosophila melanogaster
• Sequence 2: XP_011526892.1
• Gene: CNBD2 / 140894
• HGNCID: 16145
• Length: 617
• Species: Homo sapiens
• Alignment Length: 505
• Identity: 96/505 - (19%)
• Similarity: 191/505 - (37%)
• Gaps: 114/505 - (22%)

  Fly   631 DFLKSVPIFKDLAEDTLIKISDVLEETHYQRGDYIVRQGARGDTFFIISKGKVRVTIKQQDTQE- 694
            :.|:.:..:::.||...:.::.|:....:.|...|:::|.:|::|:.|..|.|.:| |.:|...
Human   150 NILQVLDSYRNYAEPLQLLLAKVMRFERFGRRRVIIKKGQKGNSFYFIYLGTVAIT-KDEDGSSA 213

  Fly   695 --EKFIRMLGKGDFFGEKALQGDDLRTANIICESADGVSCLVIDRETF--NQLISNLD-EIKHRY 754
              :...::|.||..|||..:....:|.:.|:|  .:....||:|||.|  |:|...:. :.::|:
Human   214 FLDPHPKLLHKGSCFGEMDVLHASVRRSTIVC--MEETEFLVVDREDFFANKLDQEVQKDAQYRF 276

  Fly   755 DDEGAMERRKINEEFRDINLTDLRVIATLGVGGFGRVELVQTNGDSSRSFALKQMKKSQIVETRQ 819
            :....||   :...:.|..|..|..:|.:....:|::        .|:.|.             :
Human   277 EFFRKME---LFASWSDEKLWQLVAMAKIERFSYGQL--------ISKDFG-------------E 317

  Fly   820 QQHIMSEKEIMGEANCQF--IVKLFKTFKDKKYLYMLMESCLGGELWTILRDKGNFDDSTTRFYT 882
            ...||    .:.:.:|:.  ::.|..:...:::::..:|...|..|.|.|.:           |:
Human   318 SPFIM----FISKGSCEVLRLLDLGASPSYRRWIWQHLELIDGRPLKTHLSE-----------YS 367

  Fly   883 ACVVEAFDYLHSRNIIYRDLKPENLLLNERGYVKLVDFGFAKKLQTGRKTWTFCGTPEYVAPEVI 947
            .  :|.|.....::...:|.....|...::.: .|....|::|::|...|     .|:.:.|::.
Human   368 P--MERFKEFQIKSYPLQDFSSLKLPHLKKAW-GLQGTSFSRKIRTSGDT-----LPKMLGPKIQ 424

  Fly   948 LNRGHDISADYWSL--GVLMFELLTGT----------------PPFTGSDPMRTYNIILK--GID 992
            ......|.....::  |.|..|...|.                ..|.......|..:||.  |.:
Human   425 SRPAQSIKCAMINIKPGELPKEAAVGAYVKVHTVEQGEILGLHQAFLPEGECDTRPLILMSLGNE 489

  Fly   993 AIEFPRNI----TRNASNLIKKLCRDN---PAERLGYQRGGISEIQKHKWFDGFYWWGLQNCTLE 1050
            .|...:.|    ..|...:||||.:.|   |::....|:    .:|::.|  ..:...|....:|
Human   490 LIRIRKEIFYELIDNDDEMIKKLLKLNIAFPSDEDMCQK----FLQQNSW--NIFRKDLLQLLVE 548

  Fly  1051 P-------PIKPAVKSV------------VDTTNFDDYP----PDPEGPP 1077
            |       |.:|..:.:            ::.|....||    |....||
Human   549 PCQSQLFTPNRPKKREIYNPKSVVLDLCSINKTTKPRYPIFMAPQKYLPP 598

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
for	NP_477487.1	DD_cGKI-alpha	385..432	CDD:213374
		Crp	518..>627	CDD:223736
		CAP_ED	520..629	CDD:237999
		Crp	632..>753	CDD:223736	32/126 (25%)
		CAP_ED	638..754	CDD:237999	31/121 (26%)
		S_TKc	778..1036	CDD:214567	46/286 (16%)
		STKc_cGK	783..1043	CDD:270724	46/288 (16%)
CNBD2	XP_011526892.1	Crp	151..>282	CDD:223736	33/133 (25%)
		CAP_ED	163..259	CDD:237999	27/98 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0664
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810