DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment for and LOC100498055

DIOPT Version :9

Sequence 1:	NP_477487.1	Gene:	for / 44817	FlyBaseID:	FBgn0000721	Length:	1088	Species:	Drosophila melanogaster
Sequence 2:	XP_002935815.2	Gene:	LOC100498055 / 100498055	-ID:	-	Length:	763	Species:	Xenopus tropicalis

Alignment Length:	743	Identity:	338/743 - (45%)
Similarity:	475/743 - (63%)	Gaps:	78/743 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   387 QEERFIQI---IQAKELKIQEMQRALQFKDNEIAELKSHLDKFQSVFPFSRGSAAGCAGTGGASG 448
            ::|:.:|:   ::.|.::|.::|.||.:...:.:...|...|..||.
Frog    58 KDEKILQLEKELEVKVIQIDKLQDALGYNVTQTSPKGSQKKKLLSVI------------------ 104

  Fly   449 SGAGGSGGSGPGTATGATRKSGQNFQRQRAL-GISAEPQSESSLLLEHVSFPKYD--------KD 504
                   ..||..   ...|:.:..:||:|. |:||||.|      .|...|...        ||
Frog   105 -------NQGPAQ---NNEKAAEAHRRQKAKEGVSAEPTS------RHYYNPSSQNPDVTCVRKD 153

  Fly   505 ERSRELIKAAILDNDFMKNLDLTQIREIVDCMYPVKYPAKNLIIKEGDVGSIVYVMEDGRVEVSR 569
            ..:::||..||:.|||::.|:.:.:|.:|||||...|....|:|:||..|:.:||:.||.::|.:
Frog   154 SSAKKLITGAIMSNDFLRQLEASHVRCMVDCMYERVYSKSQLVIQEGAAGNHLYVLADGLLDVIQ 218

  Fly   570 EGKYLSTLSGAKVLGELAILYNCQRTATITAITECNLWAIERQCFQTIMMRTGLIRQAEYSDFLK 634
            ..:.|..:......|||||||||:||||:.|:|:..:|.::||.||.|||.:...:..||..||:
Frog   219 NSRLLGQMHPGTAFGELAILYNCKRTATVKAVTDSKIWVLDRQVFQNIMMSSAQAQHQEYFSFLR 283

  Fly   635 SVPIFKDLAEDTLIKISDVLEETHYQRGDYIVRQGARGDTFFIISKGKVRVTIKQQDTQEEKFIR 699
            ||.:.|||.|:.|.||.|.||...|.:||||:|:|..|:|||||:||||.||...:.:||.:.|:
Frog   284 SVSLLKDLPEEKLSKIVDCLEVDFYDKGDYIIREGEEGNTFFIIAKGKVCVTQAVEGSQEPQEIK 348

  Fly   700 MLGKGDFFGEKALQGDDLRTANIICESADGVSCLVIDRETFNQLISNLDEIK---HRY------- 754
            .||.||:||||||..:|:|:||||.|. |...||||||:||||::....|::   ..|
Frog   349 TLGVGDYFGEKALISEDVRSANIIAEE-DDTQCLVIDRDTFNQMVGTYQELQTYLREYVFQLALN 412

  Fly   755 DDEGAMERRK-----INEEFRDIN--------------LTDLRVIATLGVGGFGRVELVQTNGDS 800
            |.:....|||     ::.:..::|              ...|.||.|||.|||||||||:.. |.
Frog   413 DHDRRNARRKSLHHSMSRDNSEVNQLRELVSKFSSTSPFRYLDVITTLGTGGFGRVELVKLK-DE 476

  Fly   801 SRSFALKQMKKSQIVETRQQQHIMSEKEIMGEANCQFIVKLFKTFKDKKYLYMLMESCLGGELWT 865
            ..:||||.:||..||:|.||:|:..||.|:.:.||.||::|::||:|.||:|||:|.|||||||:
Frog   477 DMTFALKCIKKKHIVDTHQQEHVYWEKNILQQINCSFIIRLYRTFRDAKYVYMLLEVCLGGELWS 541

  Fly   866 ILRDKGNFDDSTTRFYTACVVEAFDYLHSRNIIYRDLKPENLLLNERGYVKLVDFGFAKKLQTGR 930
            ||||.|.|::.|.||.|.||:|||||||:|.|:|||||||||||:..||:|:||||||||:..|:
Frog   542 ILRDTGPFEEGTARFCTGCVLEAFDYLHNRGIVYRDLKPENLLLDSEGYIKMVDFGFAKKIGPGK 606

  Fly   931 KTWTFCGTPEYVAPEVILNRGHDISADYWSLGVLMFELLTGTPPFTGSDPMRTYNIILKGIDAIE 995
            |||||||||||||||:|:|||||..|||||||:|::|||||:|||:|:||::.||::||||:.::
Frog   607 KTWTFCGTPEYVAPEIIMNRGHDFGADYWSLGILIYELLTGSPPFSGTDPIKIYNMVLKGIEKVD 671

  Fly   996 FPRNITRNASNLIKKLCRDNPAERLGYQRGGISEIQKHKWFDGFYWWGLQNCTLEPPIKPAVKSV 1060
            ||..|.|.:.::|::|||.|||||||.::.|||:|:|||||.||.|.||:|..|..|:|..:|.:
Frog   672 FPHRIGRRSEDVIRRLCRINPAERLGNRKNGISDIRKHKWFQGFNWEGLRNRKLLSPLKREIKGI 736

  Fly  1061 VDTTNFDDYPPDPEGPPPDDVTGWDKDF 1088
            .|.:.||::.|:.| .|||:::||||:|
Frog   737 TDHSYFDNFLPESE-EPPDELSGWDKNF 763

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
for	NP_477487.1	DD_cGKI-alpha	385..432	CDD:213374	11/47 (23%)
		Crp	518..>627	CDD:223736	45/108 (42%)
		CAP_ED	520..629	CDD:237999	43/108 (40%)
		Crp	632..>753	CDD:223736	65/123 (53%)
		CAP_ED	638..754	CDD:237999	61/118 (52%)
		S_TKc	778..1036	CDD:214567	163/257 (63%)
		STKc_cGK	783..1043	CDD:270724	165/259 (64%)
LOC100498055	XP_002935815.2	CAP_ED	169..278	CDD:237999	43/108 (40%)
		CAP_ED	287..402	CDD:237999	61/115 (53%)
		STKc_cGK	460..719	CDD:270724	165/259 (64%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D123183at33208
OrthoFinder	1	1.000	-	-		FOG0001832
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24353
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2508
SonicParanoid	1	1.000	-	-		X815
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	6.050