DRSC/TRiP Functional Genomics Resources

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Protein Alignment E(bx) and KDM7A

DIOPT Version :9

Sequence 1:NP_001261188.1 Gene:E(bx) / 44811 FlyBaseID:FBgn0000541 Length:2761 Species:Drosophila melanogaster
Sequence 2:NP_085150.1 Gene:KDM7A / 80853 HGNCID:22224 Length:941 Species:Homo sapiens


Alignment Length:239 Identity:66/239 - (27%)
Similarity:90/239 - (37%) Gaps:86/239 - (35%)


- Green bases have known domain annotations that are detailed below.


  Fly  2588 LYCSCRQPYDESQFYICCDKCQDWFHGRCVGILQSEAEFIDEYVCPEC----------QRKN--- 2639
            :||.||||||.::|.|.||.|:|||||.|||:.:..|..||.|.||.|          :|:|   
Human    38 VYCVCRQPYDVNRFMIECDICKDWFHGSCVGVEEHHAVDIDLYHCPNCAVLHGSSLMKKRRNWHR 102

  Fly  2640 ------DANAANMKKLTSNDVEELKN---------LIK-------QMQLHKSAW--PFMEP---- 2676
                  |..:..::..|...::||::         :||       |..|.|..:  |.|.|    
Human   103 HDYTEIDDGSKPVQAGTRTFIKELRSRVFPSADEIIIKMHGSQLTQRYLEKHGFDVPIMVPKLDD 167

  Fly  2677 ---------------------------VDPKEAPD-------YYKVIKEPMDLKRME-IKLESNT 2706
                                       :|.....|       |.|....|...|.:. |.||.:.
Human   168 LGLRLPSPTFSVMDVERYVGGDKVIDVIDVARQADSKMTLHNYVKYFMNPNRPKVLNVISLEFSD 232

  Fly  2707 YTKLSEF--IGDMTKIFDNCRYYNPKESSFYKCAEALESYFVQK 2748
             ||:||.  :.|:.|.......|.|.:|.|.|       .||||
Human   233 -TKMSELVEVPDIAKKLSWVENYWPDDSVFPK-------PFVQK 268

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
E(bx)NP_001261188.1 DDT 190..245 CDD:280886
WHIM1 288..337 CDD:292246
PHD1_BPTF 341..383 CDD:277034
BAH 361..>438 CDD:295389
TNG2 <2423..2638 CDD:227367 28/59 (47%)
PHD_SF 2533..2579 CDD:304600
PHD2_3_BPTF 2589..2635 CDD:277035 27/45 (60%)
Bromo_gcn5_like 2653..2752 CDD:99941 34/155 (22%)
KDM7ANP_085150.1 PHD_KDM7 39..88 CDD:277110 28/48 (58%)
Linker 97..114 3/16 (19%)
JmjC 234..297 CDD:214721 14/42 (33%)
cupin_like 269..369 CDD:304367 66/239 (28%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 597..633
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 677..700
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 819..921
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1632
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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