Protein Alignment E(bx) and Gcn5

DIOPT Version :9

• Sequence 1: NP_001261188.1
• Gene: E(bx) / 44811
• FlyBaseID: FBgn0000541
• Length: 2761
• Species: Drosophila melanogaster
• Sequence 2: NP_648586.2
• Gene: Gcn5 / 39431
• FlyBaseID: FBgn0020388
• Length: 813
• Species: Drosophila melanogaster
• Alignment Length: 961
• Identity: 190/961 - (19%)
• Similarity: 323/961 - (33%)
• Gaps: 317/961 - (32%)

  Fly  1949 GQQVIVK--PL-GNNQAQIVAHIKHQGDGNAHIVTSNSATAVPQANPQTSPVKQQA--LPPQSPQ 2008
            |..:.:|  |: |||.....|..:.|....|....::.|....| ||........|  :|.:..:
  Fly     4 GPSITIKSQPIDGNNTGNAAAQQQQQAANGAATAGASGAAGSAQ-NPGHGGAASGAGSVPAEGTR 67

  Fly  2009 QVVVQQQQIHQQSPTNFESGVTPITQQPV---LTQAVQA----------PAQQQALSVEESLLQN 2060
            |..:|:.|..:|...|.     |:.|:..   :..|.|:          |.:.:...||.|..
  Fly    68 QNSLQRIQQRKQKVFNL-----PVPQKLAKLSMYSACQSEGCRCTGWKTPQENRHRDVESSYC-- 125

  Fly  2061 QPPGTVIKC------------------VTAQVLQTEHGPRIVLQGL------VGNDFTAQQLQLV 2101
              |....:|                  :::..:....|..|.::.|      |.::.|.:..|.:
  Fly   126 --PEFNEECRNTSCRHSLRSHIAHLDNISSSSMNELLGAIIDMENLFMSMQRVEDEDTKKVYQYL 188

  Fly  2102 QTQVKQQLMKAQES--NGKLGVLGPTKIYLAVQPENAVQSQPPPLTPV--------------HQS 2150
            ...::|.::..|::  .|.||                   .||..||.              |.|
  Fly   189 FRLLRQCVLTRQQAVIRGPLG-------------------DPPFETPCITKAVLSLVFYKYNHLS 234

  Fly  2151 AAHQQVGGGVSIAYTRMMNSNYFVQ------EIEEEEDYDDEI-----IVVCSPP---NQIVPSP 2201
            ....|....|:..:...:|...|..      ::..|:..:.:|     :|.|..|   |.:....
  Fly   235 TPELQTMTEVAKTFLNFLNHYNFESPSTRRGDLTHEDASNYKINYTRWLVFCHVPAFCNSLRQCE 299

  Fly  2202 PREVFEGRILRSELPCRTNNNFEDQDNIEQHRLKYESEDLKRCSLQTNNIEIDADTLATTYEANS 2266
            ...||...:||:...|.:            .:||      |:|.
  Fly   300 TSLVFGRTLLRTVFQCMS------------QQLK------KKCI--------------------- 325

  Fly  2267 TIKDIAINNGDDQENSKCAETENSNITTNESFAGT--SSLLEGSEHDEPTNLAGLDISETDLENK 2329
                        .|..:..|.:.|.||....|..|  :.||   :.|.|.         .|...:
  Fly   326 ------------SERDRFPEDKRSIITLMPKFLETLRAELL---KDDSPI---------WDTSYR 366

  Fly  2330 QNESFVVTRGYIQKSISN-------ALKQGNLSPELEEKLVCMQKQQENANSTNEWETCSRGSVN 2387
            .:.|||:.:....:.::|       |...||....:.|.|....|::.....::|
  Fly   367 PSNSFVIQQRKRNQEVANVPIGPSAASIGGNKRTSVGEPLHKRIKKEPTDRPSSE---------- 421

  Fly  2388 EEALTPSRQTDDTEWKIRTSLRRPNAMTTSSQFNR--ILKKNRSKNDEVAELGEQKQSQLERH-- 2448
                    ..||....:  .:|...:::.|...|:  ||.......||..:..|||:: :|.|
  Fly   422 --------NLDDLPADV--VMRAMKSVSESKTTNKAEILFPVNVSRDENVKAEEQKRA-IEFHVV 475

  Fly  2449 -----KELLKKNILRKRSL----------LERNLQSEIHEDVKTKVQRHVRPLSNASPDEQSENE 2498
                 |.:.|:.:|....|          :.|...|::..|.|.|....::           ||:
  Fly   476 GNSLTKPVDKQTVLWLLGLQLVFAYQLPEMPREYISQLVFDTKHKTLALIK-----------ENQ 529

  Fly  2499 RSGE------PNLDFKRTEVQNPRHGAGRPKKLTRKKEKLYCICRTPYDDTKFYVGCDLCSN--- 2554
            ..|.      |:..|  ||:                   ::|.. |..:..|.| |..|.::
  Fly   530 PIGGICFRPFPSQGF--TEI-------------------VFCAV-TMSEQVKGY-GTHLMNHLKD 571

  Fly  2555 ----------WFHGDCVSITEEASKKLSEFICIDCKRARETQQLYCSCRQPYDESQFYICCDKCQ 2609
                      ....||.:|.....:..|:    |.|.||   .:|....:.|| |...:.|:...
  Fly   572 YSIQRGIKHLLTFADCDAIGYFKKQGFSK----DIKLAR---PVYAGYIKEYD-SATLMHCELHP 628

  Fly  2610 DWFHGRCVGILQSEAEFIDEYVCPECQRKNDAN-------------------------------- 2642
            ...:.:.:.:::|::|.:.|.:   .||.|:..
  Fly   629 SIVNTQFIAVIRSQSEILKELI---AQRHNEVQKVRPGLTCFKEGLPVIPVESIPGLREIGWKPQ 690

  Fly  2643 ---AANMKKL-TSNDVEEL----KNLIKQMQLHKSAWPFMEPVDPKEAPDYYKVIKEPMDLKRME 2699
               |.:.:.| .|.|.|:|    .::::.::.|.:||||:.||...|.||||..||.|||||.|.
  Fly   691 NRPARSSRPLEESTDPEKLATSFASVLQSVRQHTTAWPFLRPVTAAEVPDYYDHIKYPMDLKTMG 755

  Fly  2700 IKLESNTYTKLSEFIGDMTKIFDNCRYYNPKESSFYKCAEALESYFVQKIK 2750
            .:|:...|.....|:.||.:||.|||:||..::.:|:||.:||.||..|::
  Fly   756 ERLKKGYYQTRRLFMADMARIFSNCRFYNSPDTEYYRCANSLERYFQTKMR 806

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E(bx)	NP_001261188.1	DDT	190..245	CDD:280886
		WHIM1	288..337	CDD:292246
		PHD1_BPTF	341..383	CDD:277034
		BAH	361..>438	CDD:295389
		TNG2	<2423..2638	CDD:227367	48/250 (19%)
		PHD_SF	2533..2579	CDD:304600	10/58 (17%)
		PHD2_3_BPTF	2589..2635	CDD:277035	8/45 (18%)
		Bromo_gcn5_like	2653..2752	CDD:99941	43/102 (42%)
Gcn5	NP_648586.2	PCAF_N	73..322	CDD:283997	47/294 (16%)
		COG5076	451..807	CDD:227408	94/402 (23%)
		Acetyltransf_1	526..598	CDD:278980	16/105 (15%)
		Bromo_gcn5_like	708..808	CDD:99941	41/99 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45468253
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840