DRSC/TRiP Functional Genomics Resources

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Protein Alignment E(bx) and CXXC1

DIOPT Version :9

Sequence 1:NP_001261188.1 Gene:E(bx) / 44811 FlyBaseID:FBgn0000541 Length:2761 Species:Drosophila melanogaster
Sequence 2:NP_001095124.1 Gene:CXXC1 / 30827 HGNCID:24343 Length:660 Species:Homo sapiens


Alignment Length:255 Identity:57/255 - (22%)
Similarity:89/255 - (34%) Gaps:88/255 - (34%)


- Green bases have known domain annotations that are detailed below.


  Fly  2487 SNASPDEQSENERSGEPNLDFKRTEVQNPRHGAGRPKKLTRKKEKLYCICRTPYDDTKFYVGCDL 2551
            |:..|.:..|:.:|               .:|...|         :|||||.| |...|.:|||.
Human     6 SDPEPPDAGEDSKS---------------ENGENAP---------IYCICRKP-DINCFMIGCDN 45

  Fly  2552 CSNWFHGDCVSITEEASKKLSEFICIDC-------------KRARETQQLYCSCRQPYDE----- 2598
            |:.||||||:.|||:.:|.:.|:.|.:|             |::||.........:|.||     
Human    46 CNEWFHGDCIRITEKMAKAIREWYCRECREKDPKLEIRYRHKKSRERDGNERDSSEPRDEGGGRK 110

  Fly  2599 --------------------------------SQFYICCDKCQDWFHGRCVGILQSEAEFIDEYV 2631
                                            |...:.....|  .|.:....::..|....|  
Human   111 RPVPDPDLQRRAGSGTGVGAMLARGSASPHKSSPQPLVATPSQ--HHQQQQQQIKRSARMCGE-- 171

  Fly  2632 CPECQRKNDAN----AANMKKLTSNDVEELKNLIKQMQLH-KSAWPF----MEPVDPKEA 2682
            |..|:|..|..    ..:|||....:....|..::|.||. :.::.:    :.||.|.|:
Human   172 CEACRRTEDCGHCDFCRDMKKFGGPNKIRQKCRLRQC
QLRARESYKYFPSSLSPVTPSES 231

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
E(bx)NP_001261188.1 DDT 190..245 CDD:280886
WHIM1 288..337 CDD:292246
PHD1_BPTF 341..383 CDD:277034
BAH 361..>438 CDD:295389
TNG2 <2423..2638 CDD:227367 44/200 (22%)
PHD_SF 2533..2579 CDD:304600 24/45 (53%)
PHD2_3_BPTF 2589..2635 CDD:277035 9/82 (11%)
Bromo_gcn5_like 2653..2752 CDD:99941 8/35 (23%)
CXXC1NP_001095124.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..20 4/28 (14%)
PHD_Cfp1 28..73 CDD:277028 24/45 (53%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 84..162 9/79 (11%)
zf-CXXC 162..208 CDD:366873 10/47 (21%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 219..287 4/13 (31%)
zf-CpG_bind_C 406..640 CDD:403474
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1632
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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