DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment bsk and CDC5

DIOPT Version :9

Sequence 1:	NP_001162930.1	Gene:	bsk / 44801	FlyBaseID:	FBgn0000229	Length:	372	Species:	Drosophila melanogaster
Sequence 2:	NP_013714.1	Gene:	CDC5 / 855013	SGDID:	S000004603	Length:	705	Species:	Saccharomyces cerevisiae

Alignment Length:	316	Identity:	78/316 - (24%)
Similarity:	137/316 - (43%)	Gaps:	80/316 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    66 KRAYREFKLMKLVNHKNIIGLLNAFTPQRNLEEFQDVYLVMELM-DANLCQVIQMD--LDHDRMS 127
            |:...|.::.|.::|.||:..::.|      |:..:||:::|:. :.:|.::::..  |....:.
Yeast   124 KKLLSEIQIHKSMSHPNIVQFIDCF------EDDSNVYILLEICPNGSLMELLKRRKVLTEPEVR 182

  Fly   128 YLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKADCTLKILDFGLARTAGT------TFMMTPYVVT 186
            :...|:...||::||..:||||||..||...::..|||.|||||.....      |...||
Yeast   183 FFTTQICGAIKYMHSRRVIHRDLKLGNIFFDSNYNLKIGDFGLAAVLANESERKYTICGTP---- 243

  Fly   187 RYYRAPEVILG--MGYTENVDIWSVGCIMGEMIRGGVLFPGTDHIDQWNKIIEQLGTPSPSFMQR 249
             .|.||||::|  .|::..|||||:|.::..::.|                       .|.|..|
Yeast   244 -NYIAPEVLMGKHSGHSFEVDIWSLGVMLYALLIG-----------------------KPPFQAR 284

  Fly   250 LQPTVRNYVENRPRYTGYSFDRLFPDGLFPNDNNQNSRRKASDARNLLSKMLVIDPEQRISVDEA 314
            ...|:...::.|             |..||.|     :..:.:.:.|:..:|.:||.:|.|:.|.
Yeast   285 DVNTIYERIKCR-------------DFSFPRD-----KPISDEGKILIRDILSLDPIERPSLTEI 331

  Fly   315 LKHEYINVWYDA-------EEVDAPAPE----PYDHSVDEREHTVEQWKELIYEEV 359
            :.:    ||:..       ..|.:.||.    |.:.|:...:..:|  |.|:.|.:
Yeast   332 MDY----VWFRGTFPPSIPSTVMSEAPNFEDIPEEQSLVNFKDCME--KSLLLESM 381

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bsk	NP_001162930.1	STKc_JNK	23..359	CDD:270840	78/314 (25%)
CDC5	NP_013714.1	STKc_PLK	80..337	CDD:271001	68/268 (25%)
		POLO_box_1	510..601	CDD:240561
		POLO_box_2	613..698	CDD:240560
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910