DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment bsk and pak2

DIOPT Version :9

Sequence 1:	NP_001162930.1	Gene:	bsk / 44801	FlyBaseID:	FBgn0000229	Length:	372	Species:	Drosophila melanogaster
Sequence 2:	XP_002935145.1	Gene:	pak2 / 733718	XenbaseID:	XB-GENE-966302	Length:	518	Species:	Xenopus tropicalis

Alignment Length:	320	Identity:	82/320 - (25%)
Similarity:	143/320 - (44%)	Gaps:	65/320 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 VEVGDTNFTIHSRYINLRPIGSGAQGIVCAAYDTITQQNVAIKKLSRPFQNVTHAKRAYREFKLM 75
            |.:||..    .:|.....||.||.|.|..|.|..|.|.||||:::  .|.....:....|..:|
Frog   234 VSIGDPK----KKYTRYEKIGQGASGTVFTAIDVATGQEVAIKQIN--LQKQPKKELIINEILVM 292

  Fly    76 KLVNHKNIIGLLNAFTPQRNLEEFQDVYLVME-LMDANLCQVI-QMDLDHDRMSYLLYQMLCGIK 138
            |.:.:.||:..|::|...      .::|:||| |...:|..|: :..:|..:::.:..:.|..::
Frog   293 KELKNPNIVNFLDSFLVS------DELYVVMEYLAGGSLTDVVTETCMDEAQIAAVCRECLQALE 351

  Fly   139 HLHSAGIIHRDLKPSNIVVKADCTLKILDFGLA------RTAGTTFMMTPYVVTRYYRAPEVILG 197
            .||:..:||||:|..|:::..|.::|:.|||..      ::..:|.:.||     |:.||||:..
Frog   352 FLHANQVIHRDIKSDNVLLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTP-----YWMAPEVVTR 411

  Fly   198 MGYTENVDIWSVGCIMGEMIRGGVLFPGTDHIDQWNKIIEQLGTPSPSFMQRLQPTVRNYVENRP 262
            ..|...|||||:|.:..||:.|...:...:.: :...:|...|||.....::|.|..|::
Frog   412 KAYGPKVDIWSLGIMAIEMVEGEPPYLNENPL-RALYLIATNGTPELQKPEKLSPIFRDF----- 470

  Fly   263 RYTGYSFDRLFPDGLFPNDNNQNSRRKASDARNLLSKMLVIDPEQRISVDEALKHEYINV 322
                                              |::.|.:|.|:|.|..|.|:|.::.:
Frog   471 ----------------------------------LNRSLEMDVEKRGSARELLQHPFLKL 496

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bsk	NP_001162930.1	STKc_JNK	23..359	CDD:270840	79/308 (26%)
pak2	XP_002935145.1	PBD	67..121	CDD:334253
pak2	XP_002935145.1	STKc_PAK2	223..518	CDD:132986	82/320 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910