DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment bsk and mapk14a

DIOPT Version :9

Sequence 1:	NP_001162930.1	Gene:	bsk / 44801	FlyBaseID:	FBgn0000229	Length:	372	Species:	Drosophila melanogaster
Sequence 2:	NP_571797.1	Gene:	mapk14a / 65237	ZFINID:	ZDB-GENE-010202-2	Length:	361	Species:	Danio rerio

Alignment Length:	359	Identity:	175/359 - (48%)
Similarity:	234/359 - (65%)	Gaps:	22/359 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 YTVEVGDTNFTIHSRYINLRPIGSGAQGIVCAAYDTITQQNVAIKKLSRPFQNVTHAKRAYREFK 73
            |..||..|.:.:..:|.||.|:||||.|.||:|:|..|...||:||||||||::.||||.|||.:
Zfish    10 YRQEVNKTIWEVPVQYQNLSPVGSGAYGSVCSAFDAKTGFKVAVKKLSRPFQSIIHAKRTYRELR 74

  Fly    74 LMKLVNHKNIIGLLNAFTPQRNLEEFQDVYLVMELMDANLCQVIQ-MDLDHDRMSYLLYQMLCGI 137
            |:|.:.|:|:||||:.|||..:|:||.|||||..||.|:|..::: ..|..|.:.:|:||:|.|:
Zfish    75 LLKHMRHENVIGLLDVFTPATSLKEFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQILRGL 139

  Fly   138 KHLHSAGIIHRDLKPSNIVVKADCTLKILDFGLARTAGTTFMMTPYVVTRYYRAPEVILG-MGYT 201
            |::|||.||||||||||:.|..||.||||||||||  .|...||.||.||:|||||::|. |.|.
Zfish   140 KYIHSADIIHRDLKPSNLAVNEDCELKILDFGLAR--HTDDEMTGYVATRWYRAPEIMLNWMHYN 202

  Fly   202 ENVDIWSVGCIMGEMIRGGVLFPGTDHIDQWNKIIEQLGTPSPSFMQRLQPT--VRNYVENRPRY 264
            ..||||||||||.|::.|..||||||||:|..:|:...|||..|.:.|: |:  .|.|:.:.|:.
Zfish   203 VTVDIWSVGCIMAELLTGRTLFPGTDHINQLQQIMRLTGTPPSSLISRM-PSHEARTYISSLPQM 266

  Fly   265 TGYSFDRLFPDGLFPNDNNQNSRRKASDARNLLSKMLVIDPEQRISVDEALKHEYINVWYDAEEV 329
            .    .|.|.| :|...|.|        |.:||.||||:|.::||:..|||.|.|...::|.:
Zfish   267 P----KRNFAD-VFIGANPQ--------AVDLLEKMLVLDTDKRITAAEALAHPYFAQYHDPD-- 316

  Fly   330 DAPAPEPYDHSVDEREHTVEQWKELIYEEVMDYE 363
            |.|..||:|.|.:.||..:|:||...|||::.:|
Zfish   317 DEPEAEPFDQSFESRELDIEEWKRQTYEEMISFE 350

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bsk	NP_001162930.1	STKc_JNK	23..359	CDD:270840	169/339 (50%)
mapk14a	NP_571797.1	STKc_p38alpha	7..351	CDD:143382	175/359 (49%)
		S_TKc	25..309	CDD:214567	154/299 (52%)
		TXY	181..183		1/1 (100%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910