Protein Alignment bsk and MAPK12

DIOPT Version :9

• Sequence 1: NP_001162930.1
• Gene: bsk / 44801
• FlyBaseID: FBgn0000229
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: NP_002960.2
• Gene: MAPK12 / 6300
• HGNCID: 6874
• Length: 367
• Species: Homo sapiens
• Alignment Length: 364
• Identity: 175/364 - (48%)
• Similarity: 236/364 - (64%)
• Gaps: 22/364 - (6%)

  Fly     4 AQHQHYTVEVGDTNFTIHSRYINLRPIGSGAQGIVCAAYDTITQQNVAIKKLSRPFQNVTHAKRA 68
            |:...|..||..|.:.:.:.|.:|:|:||||.|.||:|.|..|...||||||.||||:...||||
Human     7 ARSGFYRQEVTKTAWEVRAVYRDLQPVGSGAYGAVCSAVDGRTGAKVAIKKLYRPFQSELFAKRA 71

  Fly    69 YREFKLMKLVNHKNIIGLLNAFTPQRNLEEFQDVYLVMELMDANLCQVIQMD-LDHDRMSYLLYQ 132
            |||.:|:|.:.|:|:||||:.|||...|::|.|.||||..|..:|.::::.: |..||:.:|:||
Human    72 YRELRLLKHMRHENVIGLLDVFTPDETLDDFTDFYLVMPFMGTDLGKLMKHEKLGEDRIQFLVYQ 136

  Fly   133 MLCGIKHLHSAGIIHRDLKPSNIVVKADCTLKILDFGLARTAGTTFMMTPYVVTRYYRAPEVILG 197
            ||.|::::|:||||||||||.|:.|..||.||||||||||.|.:.  ||.|||||:||||||||.
Human   137 MLKGLRYIHAAGIIHRDLKPGNLAVNEDCELKILDFGLARQADSE--MTGYVVTRWYRAPEVILN 199

  Fly   198 -MGYTENVDIWSVGCIMGEMIRGGVLFPGTDHIDQWNKIIEQLGTPSPSFMQRLQ-PTVRNYVEN 260
             |.||:.||||||||||.|||.|..||.|:||:||..:|::..|||...|:|||| ...:||::.
Human   200 WMRYTQTVDIWSVGCIMAEMITGKTLFKGSDHLDQLKEIMKVTGTPPAEFVQRLQSDEAKNYMKG 264

  Fly   261 RPRYTGYSFDRLFPDGLFPNDNNQNSRRKASD-ARNLLSKMLVIDPEQRISVDEALKHEYINVWY 324
            .|......|..:..:              ||. |.|||.||||:|.|||::..|||.|.|....:
Human   265 LPELEKKDFASILTN--------------ASPLAVNLLEKMLVLDAEQRVTAGEALAHPYFESLH 315

  Fly   325 DAEEVDAPAPEPYDHSVDEREHTVEQWKELIYEEVMDYE 363
            |.|  |.|..:.||.|.|:.:.|:::||.:.|:||:.::
Human   316 DTE--DEPQVQKYDDSFDDVDRTLDEWKRVTYKEVLSFK 352

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bsk	NP_001162930.1	STKc_JNK	23..359	CDD:270840	168/339 (50%)
MAPK12	NP_002960.2	STKc_p38gamma	11..353	CDD:143385	174/360 (48%)
		TXY	183..185		1/1 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910