DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment bsk and mapk8a

DIOPT Version :9

Sequence 1:	NP_001162930.1	Gene:	bsk / 44801	FlyBaseID:	FBgn0000229	Length:	372	Species:	Drosophila melanogaster
Sequence 2:	NP_001103859.1	Gene:	mapk8a / 562720	ZFINID:	ZDB-GENE-080218-17	Length:	427	Species:	Danio rerio

Alignment Length:	368	Identity:	278/368 - (75%)
Similarity:	318/368 - (86%)	Gaps:	1/368 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 QHQHYTVEVGDTNFTIHSRYINLRPIGSGAQGIVCAAYDTITQQNVAIKKLSRPFQNVTHAKRAY 69
            :.:.|:|:|||:.||:..||.||||||||||||||:|||...::|||||||||||||.|||||||
Zfish     7 EKEFYSVDVGDSTFTVLKRYQNLRPIGSGAQGIVCSAYDNNLERNVAIKKLSRPFQNQTHAKRAY 71

  Fly    70 REFKLMKLVNHKNIIGLLNAFTPQRNLEEFQDVYLVMELMDANLCQVIQMDLDHDRMSYLLYQML 134
            ||..|||.|||||||||||.||||:.||||||||||||||||||||||||:|||:|:||||||||
Zfish    72 RELVLMKCVNHKNIIGLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQMELDHERLSYLLYQML 136

  Fly   135 CGIKHLHSAGIIHRDLKPSNIVVKADCTLKILDFGLARTAGTTFMMTPYVVTRYYRAPEVILGMG 199
            |||||||:||||||||||||||||:|||||||||||||||.|..:||||||||||||||||||||
Zfish   137 CGIKHLHAAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAATGLLMTPYVVTRYYRAPEVILGMG 201

  Fly   200 YTENVDIWSVGCIMGEMIRGGVLFPGTDHIDQWNKIIEQLGTPSPSFMQRLQPTVRNYVENRPRY 264
            |..|||:|||||||.||:||.|||||:||||||||:|||||||:..|:.:|..:||.||||||||
Zfish   202 YQANVDVWSVGCIMAEMVRGSVLFPGSDHIDQWNKVIEQLGTPTQEFLLKLNQSVRTYVENRPRY 266

  Fly   265 TGYSFDRLFPDGLFPNDNNQNSRRKASDARNLLSKMLVIDPEQRISVDEALKHEYINVWYDAEEV 329
            |||||::||||.|||.| :::|:.|||.||:|||||||||..:||||||||:|.|||||||..||
Zfish   267 TGYSFEKLFPDVLFPAD-SEHSKLKASQARDLLSKMLVIDASKRISVDEALQHPYINVWYDPAEV 330

  Fly   330 DAPAPEPYDHSVDEREHTVEQWKELIYEEVMDYEAHNTNNRTR 372
            :||:|...|..:||||||||:||||||:||:|:|....|...|
Zfish   331 EAPSPLITDKQLDEREHTVEEWKELIYKEVLDWEERMKNGVIR 373

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bsk	NP_001162930.1	STKc_JNK	23..359	CDD:270840	265/335 (79%)
mapk8a	NP_001103859.1	STKc_JNK	25..360	CDD:270840	265/335 (79%)
mapk8a	NP_001103859.1	S_TKc	26..321	CDD:214567	237/295 (80%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	504	1.000	Domainoid score	I324
eggNOG	1	0.900	-	-		E1_KOG0665
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H56760
Inparanoid	1	1.050	587	1.000	Inparanoid score	I955
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D295851at33208
OrthoFinder	1	1.000	-	-		FOG0001812
OrthoInspector	1	1.000	-	-		otm25234
orthoMCL	1	0.900	-	-		OOG6_103172
Panther	1	1.100	-	-	O	PTHR24055
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4615
SonicParanoid	1	1.000	-	-		X1172
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	15	14.860