Protein Alignment bsk and MAPK8

DIOPT Version :9

• Sequence 1: NP_001162930.1
• Gene: bsk / 44801
• FlyBaseID: FBgn0000229
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: NP_001265476.1
• Gene: MAPK8 / 5599
• HGNCID: 6881
• Length: 427
• Species: Homo sapiens
• Alignment Length: 364
• Identity: 290/364 - (79%)
• Similarity: 322/364 - (88%)
• Gaps: 1/364 - (0%)

  Fly     9 YTVEVGDTNFTIHSRYINLRPIGSGAQGIVCAAYDTITQQNVAIKKLSRPFQNVTHAKRAYREFK 73
            |:||:||:.||:..||.||:|||||||||||||||.|.::|||||||||||||.|||||||||..
Human    11 YSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRPFQNQTHAKRAYRELV 75

  Fly    74 LMKLVNHKNIIGLLNAFTPQRNLEEFQDVYLVMELMDANLCQVIQMDLDHDRMSYLLYQMLCGIK 138
            |||.|||||||||||.||||::||||||||:|||||||||||||||:|||:||||||||||||||
Human    76 LMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQMELDHERMSYLLYQMLCGIK 140

  Fly   139 HLHSAGIIHRDLKPSNIVVKADCTLKILDFGLARTAGTTFMMTPYVVTRYYRAPEVILGMGYTEN 203
            ||||||||||||||||||||:|||||||||||||||||:|||||||||||||||||||||||.||
Human   141 HLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGMGYKEN 205

  Fly   204 VDIWSVGCIMGEMIRGGVLFPGTDHIDQWNKIIEQLGTPSPSFMQRLQPTVRNYVENRPRYTGYS 268
            ||||||||||||||:||||||||||||||||:|||||||.|.||::||||||.||||||:|.|||
Human   206 VDIWSVGCIMGEMIKGGVLFPGTDHIDQWNKVIEQLGTPCPEFMKKLQPTVRTYVENRPKYAGYS 270

  Fly   269 FDRLFPDGLFPNDNNQNSRRKASDARNLLSKMLVIDPEQRISVDEALKHEYINVWYDAEEVDAPA 333
            |::||||.|||.|:..| :.|||.||:|||||||||..:||||||||:|.|||||||..|.:||.
Human   271 FEKLFPDVLFPADSEHN-KLKASQARDLLSKMLVIDASKRISVDEALQHPYINVWYDPSEAEAPP 334

  Fly   334 PEPYDHSVDEREHTVEQWKELIYEEVMDYEAHNTNNRTR 372
            |:..|..:||||||:|:||||||:||||.|....|...|
Human   335 PKIPDKQLDEREHTIEEWKELIYKEVMDLEERTKNGVIR 373

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bsk	NP_001162930.1	STKc_JNK	23..359	CDD:270840	276/335 (82%)
MAPK8	NP_001265476.1	STKc_JNK	25..360	CDD:270840	276/335 (82%)
		TXY	183..185		1/1 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	371..427		1/3 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	504	1.000	Domainoid score	I334
eggNOG	1	0.900	-	-		E1_KOG0665
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H56760
Inparanoid	1	1.050	594	1.000	Inparanoid score	I977
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D295851at33208
OrthoFinder	1	1.000	-	-		FOG0001812
OrthoInspector	1	1.000	-	-		otm40681
orthoMCL	1	0.900	-	-		OOG6_103172
Panther	1	1.100	-	-	LDO	PTHR24055
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4615
SonicParanoid	1	1.000	-	-		X1172
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	14	13.860