Protein Alignment bsk and MAPK8

DIOPT Version :10

• Sequence 1: NP_723541.1
• Gene: bsk / 44801
• FlyBaseID: FBgn0000229
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: NP_620637.1
• Gene: MAPK8 / 5599
• HGNCID: 6881
• Length: 427
• Species: Homo sapiens
• Alignment Length: 364
• Identity: 283/364 - (77%)
• Similarity: 318/364 - (87%)
• Gaps: 1/364 - (0%)

  Fly     9 YTVEVGDTNFTIHSRYINLRPIGSGAQGIVCAAYDTITQQNVAIKKLSRPFQNVTHAKRAYREFK 73
            |:||:||:.||:..||.||:|||||||||||||||.|.::|||||||||||||.|||||||||..
Human    11 YSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRPFQNQTHAKRAYRELV 75

  Fly    74 LMKLVNHKNIIGLLNAFTPQRNLEEFQDVYLVMELMDANLCQVIQMDLDHDRMSYLLYQMLCGIK 138
            |||.|||||||||||.||||::||||||||:|||||||||||||||:|||:||||||||||||||
Human    76 LMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQMELDHERMSYLLYQMLCGIK 140

  Fly   139 HLHSAGIIHRDLKPSNIVVKADCTLKILDFGLARTAGTTFMMTPYVVTRYYRAPEVILGMGYTEN 203
            ||||||||||||||||||||:|||||||||||||||||:|||||||||||||||||||||||.||
Human   141 HLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGMGYKEN 205

  Fly   204 VDIWSVGCIMGEMIRGGVLFPGTDHIDQWNKIIEQLGTPSPSFMQRLQPTVRNYVENRPRYTGYS 268
            ||:||||||||||:...:||||.|:||||||:|||||||.|.||::||||||.||||||:|.|||
Human   206 VDLWSVGCIMGEMVCHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQPTVRTYVENRPKYAGYS 270

  Fly   269 FDRLFPDGLFPNDNNQNSRRKASDARNLLSKMLVIDPEQRISVDEALKHEYINVWYDAEEVDAPA 333
            |::||||.|||.|:..| :.|||.||:|||||||||..:||||||||:|.|||||||..|.:||.
Human   271 FEKLFPDVLFPADSEHN-KLKASQARDLLSKMLVIDASKRISVDEALQHPYINVWYDPSEAEAPP 334

  Fly   334 PEPYDHSVDEREHTVEQWKELIYEEVMDYEAHNTNNRTR 372
            |:..|..:||||||:|:||||||:||||.|....|...|
Human   335 PKIPDKQLDEREHTIEEWKELIYKEVMDLEERTKNGVIR 373

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bsk	NP_723541.1	STKc_JNK	23..359	CDD:270840	269/335 (80%)
MAPK8	NP_620637.1	STKc_JNK	25..360	CDD:270840	269/335 (80%)
		TXY	183..185		1/1 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	371..427		1/3 (33%)