Protein Alignment bsk and MAPK3

DIOPT Version :10

• Sequence 1: NP_723541.1
• Gene: bsk / 44801
• FlyBaseID: FBgn0000229
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: NP_002737.2
• Gene: MAPK3 / 5595
• HGNCID: 6877
• Length: 379
• Species: Homo sapiens
• Alignment Length: 357
• Identity: 144/357 - (40%)
• Similarity: 222/357 - (62%)
• Gaps: 31/357 - (8%)

  Fly    18 FTIHSRYINLRPIGSGAQGIVCAAYDTITQQNVAIKKLSRPFQNVTHAKRAYREFKLMKLVNHKN 82
            |.:..||..|:.||.||.|:|.:|||.:.:..|||||:| ||::.|:.:|..||.:::....|:|
Human    36 FDVGPRYTQLQYIGEGAYGMVSSAYDHVRKTRVAIKKIS-PFEHQTYCQRTLREIQILLRFRHEN 99

  Fly    83 IIG---LLNAFTPQRNLEEFQDVYLVMELMDANLCQVIQ-MDLDHDRMSYLLYQMLCGIKHLHSA 143
            :||   :|.|.|    ||..:|||:|.:||:.:|.:::: ..|.:|.:.|.|||:|.|:|::|||
Human   100 VIGIRDILRAST----LEAMRDVYIVQDLMETDLYKLLKSQQLSNDHICYFLYQILRGLKYIHSA 160

  Fly   144 GIIHRDLKPSNIVVKADCTLKILDFGLARTAGT----TFMMTPYVVTRYYRAPEVIL-GMGYTEN 203
            .::||||||||:::...|.|||.||||||.|..    |..:|.||.||:|||||::| ..|||::
Human   161 NVLHRDLKPSNLLINTTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKS 225

  Fly   204 VDIWSVGCIMGEMIRGGVLFPGTDHIDQWNKIIEQLGTPSPSFMQ-RLQPTVRNYVENRPRYTGY 267
            :||||||||:.||:....:|||..::||.|.|:..||:||...:. .:....|||:::.|..|..
Human   226 IDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINMKARNYLQSLPSKTKV 290

  Fly   268 SFDRLFPDGLFPNDNNQNSRRKASDARNLLSKMLVIDPEQRISVDEALKHEYINVWYDAEEVDAP 332
            ::.:|||             :..|.|.:||.:||..:|.:||:|:|||.|.|:..:||  ..|.|
Human   291 AWAKLFP-------------KSDSKALDLLDRMLTFNPNKRITVEEALAHPYLEQYYD--PTDEP 340

  Fly   333 -APEPYDHSVDEREHTVEQWKELIYEEVMDYE 363
             |.||:..:::..:...|:.||||::|...::
Human   341 VAEEPFTFAMELDDLPKERLKELIFQETARFQ 372

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bsk	NP_723541.1	STKc_JNK	23..359	CDD:270840	142/346 (41%)
MAPK3	NP_002737.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..26
		STKc_ERK1_2_like	36..370	CDD:270839	144/353 (41%)
		TXY	202..204		1/1 (100%)