DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment bsk and pak5

DIOPT Version :9

Sequence 1:	NP_001162930.1	Gene:	bsk / 44801	FlyBaseID:	FBgn0000229	Length:	372	Species:	Drosophila melanogaster
Sequence 2:	NP_998127.1	Gene:	pak5 / 405898	ZFINID:	ZDB-GENE-040426-2085	Length:	711	Species:	Danio rerio

Alignment Length:	326	Identity:	81/326 - (24%)
Similarity:	147/326 - (45%)	Gaps:	61/326 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 HQHY------TVEVGDTNFTIHSRYINLRPIGSGAQGIVCAAYDTITQQNVAIKKLSRPFQNVTH 64
            |:.:      .||.||....:.|    ...||.|:.||||.|.:..:.:.||:||:.  .:....
Zfish   421 HEQFRAALQLVVEPGDPRQGLDS----FLKIGEGSTGIVCIATEKHSGKQVAVKKMD--LRKQQR 479

  Fly    65 AKRAYREFKLMKLVNHKNIIGLLNAFTPQRNLEEFQDVYLVMELMDANLCQ--VIQMDLDHDRMS 127
            .:..:.|..:|:..:|:|::.:.|::...      .::::|||.::.....  |....::.::::
Zfish   480 RELLFNEVVIMRDYHHENVVDMYNSYLVG------DELWVVMEFLEGGALTDIVTHTRMNEEQIA 538

  Fly   128 YLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKADCTLKILDFGL-ARTAGTTFMMTPYVVTRYYRA 191
            .:...:|..:.:||:.|:||||:|..:|::.:|..:|:.|||. |:.:.........|.|.|:.|
Zfish   539 TVCLSVLKALSYLHTQGVIHRDIKSDSILLTSDGRIKLSDFGFCAQVSKEVPKRKSLVGTPYWMA 603

  Fly   192 PEVILGMGYTENVDIWSVGCIMGEMIRGGVLFPGTDHIDQWNKIIEQLGTPSPSFMQRLQPTVRN 256
            ||||..:.|...|||||:|.::.||:.|                      ..|.|.:.....:|.
Zfish   604 PEVISRLPYGTEVDIWSLGIMVIEMVDG----------------------EPPYFNEPPLQAMRR 646

  Fly   257 YVENRPRYTGYSFDRLFPDGLFPNDNNQNSRRKASDARNLLSKMLVIDPEQRISVDEALKHEYIN 321
            ..:|.|       .||           :.|.:.:|..|..|..|||.:|.||.|..|.|::.::.
Zfish   647 IRDNLP-------PRL-----------KESHKVSSVLRAFLDLMLVREPSQRASALELLQNPFLK 693

  Fly   322 V 322
            :
Zfish   694 L 694

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bsk	NP_001162930.1	STKc_JNK	23..359	CDD:270840	75/303 (25%)
pak5	NP_998127.1	CRIB_PAK_like	9..55	CDD:238526
		STKc_PAK5	418..709	CDD:132989	81/326 (25%)
		S_TKc	446..692	CDD:214567	75/293 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910