DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment bsk and madd-3

DIOPT Version :9

Sequence 1:	NP_001162930.1	Gene:	bsk / 44801	FlyBaseID:	FBgn0000229	Length:	372	Species:	Drosophila melanogaster
Sequence 2:	NP_001368709.1	Gene:	madd-3 / 3565068	WormBaseID:	WBGene00006517	Length:	890	Species:	Caenorhabditis elegans

Alignment Length:	373	Identity:	92/373 - (24%)
Similarity:	165/373 - (44%)	Gaps:	91/373 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 QHQ-----HYTVEVGD---TNFTIHSRYINLRPIGSGAQGIVCAAYDTITQQNVAIKKLSRPFQN 61
            |||     |.....||   ..|||:.      .:|.|..|.|....|:::...:|:|.:    :|
Worm   530 QHQDDKDGHLIYSKGDFILNRFTIYD------TLGEGTFGKVVRVNDSLSDTFMALKII----KN 584

  Fly    62 VTHAKRAYR-EFKLMKLVNHKNIIGLLNAFTPQR-----NLEEFQD----VYLVMELMDANLCQV 116
            |:..:.|.: |.|:::.:..|:         |::     ::..:.|    :.|:.:||.:::...
Worm   585 VSKYREAAKLEVKVLQKLAEKD---------PEKKNWVIHMGSYFDYNGHICLLFDLMGSSIFDF 640

  Fly   117 IQMDLDH------DRMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIV-----------------VK 158
            ::  .:|      ::..::.:|:...:|.||...:.|.||||.||:                 |.
Worm   641 LK--ANHYKPYPMEQTLHITWQLCNAVKFLHDNKLTHTDLKPENILFVDSRYTTKLVDKKPLRVL 703

  Fly   159 ADCTLKILDFGLARTAGTTFMMTPY---VVTRYYRAPEVILGMGYTENVDIWSVGCIMGEMIRGG 220
            ....::::|||.|     ||....:   |.||:||||||||.:|:::..|:||:|||:.|:..|.
Worm   704 HSTHVRLIDFGSA-----TFDHEHHSIIVSTRHYRAPEVILELGWSQPCDVWSIGCILYELYTGV 763

  Fly   221 VLF---PGTDHIDQWNKIIEQLGTPSPSFMQRLQPTVRN--YVENRPRYTGYSFDRLFPDGLFPN 280
            .||   ...:|:....:::..:    |..|.:...|.|.  ::..|..:...|     .|..:..
Worm   764 TLFQTHENREHLAMMERVLGDI----PLRMAKRTNTFRTKFFINGRLDWVNTS-----ADAAYVR 819

  Fly   281 DNNQNSRRKAS-------DARNLLSKMLVIDPEQRISVDEALKHEYIN 321
            ||.:..||..|       :...|:..||:.:|..|:.:.|||:|.|.|
Worm   820 DNCKPLRRSMSCTDPEHVELFELIENMLMFEPLARMKLPEALQHRYFN 867

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bsk	NP_001162930.1	STKc_JNK	23..359	CDD:270840	83/347 (24%)
madd-3	NP_001368709.1	PHA03247	<73..364	CDD:223021
madd-3	NP_001368709.1	PKc_CLK	538..866	CDD:271036	87/362 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910