DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment bsk and jnk-1

DIOPT Version :9

Sequence 1:	NP_001162930.1	Gene:	bsk / 44801	FlyBaseID:	FBgn0000229	Length:	372	Species:	Drosophila melanogaster
Sequence 2:	NP_001021270.1	Gene:	jnk-1 / 177460	WormBaseID:	WBGene00002178	Length:	463	Species:	Caenorhabditis elegans

Alignment Length:	355	Identity:	256/355 - (72%)
Similarity:	298/355 - (83%)	Gaps:	2/355 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 HYTVEVGDTNFTIHSRYINLRPIGSGAQGIVCAAYDTITQQNVAIKKLSRPFQNVTHAKRAYREF 72
            :|:|.:|:....:..||.|||.||||||||||:|:||:..:.||||||||||||||||||||||.
Worm   103 YYSVTIGEAQMVVLKRYQNLRLIGSGAQGIVCSAFDTVRNEQVAIKKLSRPFQNVTHAKRAYREL 167

  Fly    73 KLMKLVNHKNIIGLLNAFTPQRNLEEFQDVYLVMELMDANLCQVIQMDLDHDRMSYLLYQMLCGI 137
            |||.|||||||||:||.||||:.|:||.|:|:|||||||||||||||||||:|:|||||||||||
Worm   168 KLMSLVNHKNIIGILNCFTPQKKLDEFNDLYIVMELMDANLCQVIQMDLDHERLSYLLYQMLCGI 232

  Fly   138 KHLHSAGIIHRDLKPSNIVVKADCTLKILDFGLARTAGTTFMMTPYVVTRYYRAPEVILGMGYTE 202
            :|||||||||||||||||||::|||||||||||||||...|||||||||||||||||||||||.|
Worm   233 RHLHSAGIIHRDLKPSNIVVRSDCTLKILDFGLARTAIEAFMMTPYVVTRYYRAPEVILGMGYKE 297

  Fly   203 NVDIWSVGCIMGEMIRGGVLFPGTDHIDQWNKIIEQLGTPSPSFMQRLQPTVRNYVENRPRYTGY 267
            |||:||:|||.||:|||.|||||.||||||.:||||||||..||::||||||||||||||||...
Worm   298 NVDVWSIGCIFGELIRGRVLFPGGDHIDQWTRIIEQLGTPDRSFLERLQPTVRNYVENRPRYQAT 362

  Fly   268 SFDRLFPDGLFPNDNNQNSRRKASDARNLLSKMLVIDPEQRISVDEALKHEYINVWYDAEEVDAP 332
            .|:.||.|.:||. ...:||...:.||:|||:|||||||:|||||:||:|.|:|||:|..||.||
Worm   363 PFEVLFSDNMFPM-TADSSRLTGAQARDLLSRMLVIDPERRISVDDALRHPYVNVWFDEIEVYAP 426

  Fly   333 APEPYDHSVDEREHTVEQWKELIYEEVMDY 362
            .|.||||::|. |..|:.|:|.|:.|:.||
Worm   427 PPLPYDHNMDV-EQNVDSWREHIFRELTDY 455

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bsk	NP_001162930.1	STKc_JNK	23..359	CDD:270840	250/335 (75%)
jnk-1	NP_001021270.1	STKc_JNK	118..452	CDD:270840	250/335 (75%)
jnk-1	NP_001021270.1	S_TKc	119..414	CDD:214567	229/295 (78%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160158396
Domainoid	1	1.000	476	1.000	Domainoid score	I206
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H56760
Inparanoid	1	1.050	534	1.000	Inparanoid score	I654
Isobase	1	0.950	-	0	Normalized mean entropy	S644
OMA	1	1.010	-	-		QHG53505
OrthoDB	1	1.010	-	-		D295851at33208
OrthoFinder	1	1.000	-	-		FOG0001812
OrthoInspector	1	1.000	-	-		oto18787
orthoMCL	1	0.900	-	-		OOG6_103172
Panther	1	1.100	-	-	LDO	PTHR24055
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4615
SonicParanoid	1	1.000	-	-		X1172
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	16	15.890