DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment bsk and nlk

DIOPT Version :9

Sequence 1:	NP_001162930.1	Gene:	bsk / 44801	FlyBaseID:	FBgn0000229	Length:	372	Species:	Drosophila melanogaster
Sequence 2:	NP_001116885.1	Gene:	nlk / 100144638	XenbaseID:	XB-GENE-483544	Length:	534	Species:	Xenopus tropicalis

Alignment Length:	400	Identity:	131/400 - (32%)
Similarity:	207/400 - (51%)	Gaps:	73/400 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 QHQHYTVEVGDTNFTIHSRYINL---RPIGSGAQGIVCAAYDTITQQNVAIKKLSRPFQNVTHAK 66
            ||.|            |::.:::   ||||.||.|:|.:..|....:.||:||:...|||:...|
Frog   135 QHSH------------HAQQLDIEPDRPIGYGAFGVVWSVTDPRDGKRVALKKMPNVFQNLVSCK 187

  Fly    67 RAYREFKLMKLVNHKNIIGLLNAFTPQRNLEEFQDVYLVMELMDANLCQVI--QMDLDHDRMSYL 129
            |.:||.|::....|.|::..|:...|. :::.|:::|:|.|||.::|.::|  ...|..|.:...
Frog   188 RVFRELKMLCFFKHDNVLSALDILQPP-HIDYFEEIYVVTELMQSDLHKIIVSPQPLSSDHVKVF 251

  Fly   130 LYQMLCGIKHLHSAGIIHRDLKPSNIVVKADCTLKILDFGLART--AGTTFMMTPYVVTRYYRAP 192
            |||:|.|:|:||||||:|||:||.|::|.::|.|||.||||||.  ...:..||..|||:|||||
Frog   252 LYQILRGLKYLHSAGILHRDIKPGNLLVNSNCVLKICDFGLARVEELDESRHMTQEVVTQYYRAP 316

  Fly   193 EVILG-MGYTENVDIWSVGCIMGEMIRGGVLFPGTDHIDQWNKIIEQLGTPSPSFMQRLQPTVRN 256
            |:::| ..||..:|:||||||..|::...:||.....|.|.:.|.:.|||||...|:......:.
Frog   317 EILMGSRHYTNAIDVWSVGCIFAELLGRRILFQAQSPIQQLDLITDLLGTPSLEAMRTACEGAKA 381

  Fly   257 YVENRPR--------YTGYSFDRLFPDGLFPNDNNQNSRRKASDARNLLSKMLVIDPEQRISVDE 313
            ::...|.        ||                   .|.:...:|.:||.:|||.||.:|||..:
Frog   382 HILRGPHKQPSLPVLYT-------------------LSSQATHEAVHLLCRMLVFDPSKRISAKD 427

  Fly   314 ALKHEYIN---VWY-------------------DAEEVDAPAPEPYDHSVDEREHTVEQWKELIY 356
            ||.|.|::   :.|                   |.|.:..|   .:|.:.::...:|.|.||:|:
Frog   428 ALAHPYLDEGRLRYHTCMCKCCFSTSSGRVYTSDFEPITNP---KFDDTFEKNLSSVRQVKEIIH 489

  Fly   357 EEVMDYEAHN 366
            :.:::.:..|
Frog   490 QFILEQQKGN 499

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bsk	NP_001162930.1	STKc_JNK	23..359	CDD:270840	126/373 (34%)
nlk	NP_001116885.1	STKc_NLK	144..515	CDD:173748	126/378 (33%)
nlk	NP_001116885.1	S_TKc	146..434	CDD:214567	115/307 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D741207at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920