DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment eEF1gamma and gstB

DIOPT Version :9

Sequence 1:	NP_001189308.1	Gene:	eEF1gamma / 44791	FlyBaseID:	FBgn0029176	Length:	431	Species:	Drosophila melanogaster
Sequence 2:	NP_415359.4	Gene:	gstB / 945469	ECOCYCID:	G6438	Length:	208	Species:	Escherichia coli

Alignment Length:	209	Identity:	52/209 - (24%)
Similarity:	92/209 - (44%)	Gaps:	28/209 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 VKGTLYTYPENFRAYKALIAAQYSGAQVKVADNFKFGETNKSAEFLKKFPGGKVPAFETAEGQ-Y 65
            ||..|.|..|....|:.::|.:            :|| .|..|:||...|.|.||.....|.. .
E. coli    13 VKKVLLTLEELELPYEQILAGR------------EFG-INHDADFLAMNPNGLVPLLRDDESDLI 64

  Fly    66 LSESNAIAYLLANEQLRGGK-----CPFVQAQVQQWISFADNEIVPASCAWVFPLLGILPQQKNS 125
            |.|||||...||.:.  |.|     .|..:|:.::|:.:|:..:..|....:..|:...|::::.
E. coli    65 LWESNAIVRYLAAQY--GQKRLWIDSPARRAEAEKWMDWANQTLSNAHRGILMGLVRTPPEERDQ 127

  Fly   126 TA----KQEAEAVLQQLNQKLQDATFLAGERITLADIVVFSSLLHLYEYVLEPSVRSAFGNVNRW 186
            .|    .:|.:|:...|:.:|....:.:|:...:.||.:...:.:|:...|..:.|.   |:.||
E. coli   128 AAIDASCKECDALFALLDAELAKVKWFSGDEFGVGDIAIAPFIYNLFNVGLTWTPRP---NLQRW 189

  Fly   187 FVTILNQKQVQAVV 200
            :..:..:..|:.||
E. coli   190 YQQLTERPAVRKVV 203

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
eEF1gamma	NP_001189308.1	GST_N_EF1Bgamma	4..79	CDD:239342	24/75 (32%)
		GstA	5..187	CDD:223698	46/191 (24%)
		GST_C_EF1Bgamma_like	90..209	CDD:198290	23/115 (20%)
		EF1G	271..376	CDD:279041
gstB	NP_415359.4	GstA	2..202	CDD:223698	50/206 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0625
Hieranoid	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
	2	1.810