DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment eEF1gamma and GTT1

DIOPT Version :9

Sequence 1:	NP_001189308.1	Gene:	eEF1gamma / 44791	FlyBaseID:	FBgn0029176	Length:	431	Species:	Drosophila melanogaster
Sequence 2:	NP_012304.1	Gene:	GTT1 / 854856	SGDID:	S000001477	Length:	234	Species:	Saccharomyces cerevisiae

Alignment Length:	226	Identity:	38/226 - (16%)
Similarity:	85/226 - (37%)	Gaps:	53/226 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 ENFRAYKALIAAQYSGAQVKVADNFKFGETNKSAEFLKKFPGGKVPAF-----ETAEGQYLSESN 70
            ::.||::.|....:...:.::....:........|..|..|.|:.|..     ||.:.:.|:||.
Yeast    12 DHSRAFRLLWLLDHLNLEYEIVPYKRDANFRAPPELKKIHPLGRSPLLEVQDRETGKKKILAESG 76

  Fly    71 AI----------AYLLANEQLRGGKCPFVQAQVQQWISFADNEIVPASCAWVFPLL--GILPQQK 123
            .|          :::|.:|...      :..|:..::.:.:..:.|       ||:  .||.:.|
Yeast    77 FIFQYVLQHFDHSHVLMSEDAD------IADQINYYLFYVEGSLQP-------PLMIEFILSKVK 128

  Fly   124 NSTAKQEAEAVLQQLNQKLQDA----------TFLAGE-----------RITLADIVVFSSLLHL 167
            :|........:.:::..|:..|          .|:.||           :::.|||::...|...
Yeast   129 DSGMPFPISYLARKVADKISQAYSSGEVKNQFDFVEGEISKNNGYLVDGKLSGADILMSFPLQMA 193

  Fly   168 YEYVLEPSVRSAFGNVNRWFVTILNQKQVQA 198
            :|...  :....:..:::|..||.:::...|
Yeast   194 FERKF--AAPEDYPAISKWLKTITSEESYAA 222

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
eEF1gamma	NP_001189308.1	GST_N_EF1Bgamma	4..79	CDD:239342	15/82 (18%)
		GstA	5..187	CDD:223698	34/213 (16%)
		GST_C_EF1Bgamma_like	90..209	CDD:198290	22/132 (17%)
		EF1G	271..376	CDD:279041
GTT1	NP_012304.1	GST_N_GTT1_like	6..87	CDD:239344	14/74 (19%)
GTT1	NP_012304.1	GST_C_GTT1_like	93..218	CDD:198298	22/139 (16%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0625
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900