DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment eEF1gamma and eprs1

DIOPT Version :9

Sequence 1:	NP_001189308.1	Gene:	eEF1gamma / 44791	FlyBaseID:	FBgn0029176	Length:	431	Species:	Drosophila melanogaster
Sequence 2:	XP_009291485.1	Gene:	eprs1 / 562037	ZFINID:	ZDB-GENE-030131-638	Length:	1690	Species:	Danio rerio

Alignment Length:	236	Identity:	47/236 - (19%)
Similarity:	84/236 - (35%)	Gaps:	68/236 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 GTLYTYPENFRAYKALIAAQYSGAQVKVADNFKFGETNKSAEFLKKFPGGKVPAFETAEGQYLSE 68
            |.|.| .|:.:....|...:.....:.|:|..:|.:.|....:|.:.    .||.    |.|
Zfish    15 GALLT-AEHVKGSVNLSVEEGKDTMLHVSDQVQFSDVNSITRYLARV----APAL----GLY--- 67

  Fly    69 SNAIAYLLANEQLRGGKCPFVQAQVQQWISFADNEIVPASCAWVFPLLGILPQQKNSTAKQEAEA 133
                           |.....|.:|..|:.|:...:    |                 .:.:..:
Zfish    68 ---------------GSNMMEQTEVDHWLEFSARRL----C-----------------GQSDLSS 96

  Fly   134 VLQQLNQKLQDATFLAGERITLADIVVFSSLLHLYEYVLEPSVRSAFGNVNRWFVTILNQKQVQA 198
            .|..|::.|...|||.|..:||||:.::::|....|...:|   |:..::.|||..:.:|....:
Zfish    97 ALADLDKALALRTFLVGRSVTLADLCIWAALKGNGESQAKP---SSHPHLCRWFSFLSSQVPFSS 158

  Fly   199 VVKDYKLCEKALVFDPKKYAEFQAKTGAAKPQQQAQQQKQE 239
            |              ..|:|   :|..|:|.....:.:||:
Zfish   159 V--------------GSKWA---SKVSASKAASVEKDKKQD 182

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
eEF1gamma	NP_001189308.1	GST_N_EF1Bgamma	4..79	CDD:239342	14/74 (19%)
		GstA	5..187	CDD:223698	35/181 (19%)
		GST_C_EF1Bgamma_like	90..209	CDD:198290	25/118 (21%)
		EF1G	271..376	CDD:279041
eprs1	XP_009291485.1	PLN02907	1..717	CDD:215492	47/236 (20%)
		GST_C_GluProRS_N	73..153	CDD:198342	23/103 (22%)
		tRNA-synt_1c	196..497	CDD:279135
		tRNA-synt_1c_C	510..687	CDD:281883
		Med25_SD1	716..901	CDD:288132
		WEPRS_RNA	762..811	CDD:238473
		WHEP-TRS	841..892	CDD:278865
		WEPRS_RNA	911..960	CDD:238473
		WEPRS_RNA	996..1045	CDD:238473
		WHEP-TRS	1080..1132	CDD:278865
		PRK08661	1197..1690	CDD:236327
		ProRS_core_arch_euk	1201..1464	CDD:238401
		ProRS_anticodon_zinc	1470..1690	CDD:238439
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910