DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment eEF1gamma and MARS1

DIOPT Version :9

Sequence 1:NP_001189308.1 Gene:eEF1gamma / 44791 FlyBaseID:FBgn0029176 Length:431 Species:Drosophila melanogaster
Sequence 2:NP_004981.2 Gene:MARS1 / 4141 HGNCID:6898 Length:900 Species:Homo sapiens


Alignment Length:335 Identity:72/335 - (21%)
Similarity:126/335 - (37%) Gaps:86/335 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly    54 KVPAFETAEGQYLSESNAIA---YLLAN-EQLRGGKCPFVQAQVQQWISFADNEIVPASCAWVFP 114
            |||..:...|.||..::||.   :||:. ||         .....||:.:...|:.||..|.::.
Human    47 KVPVLQLDSGNYLFSTSAICRYFFLLSGWEQ---------DDLTNQWLEWEATELQPALSAALYY 102

  Fly   115 LLGILPQQKNSTAKQEAEAVLQQLNQKL--QDATFLAGERITLADIVVFSSLLHLYEYVLEPS-V 176
            |  ::..:|...........|..::..|  |:..|||||..:|||||::.:   ||..:.:|: :
Human   103 L--VVQGKKGEDVLGSVRRALTHIDHSLSRQNCPFLAGETESLADIVLWGA---LYPLLQDPAYL 162

  Fly   177 RSAFGNVNRWFVTILNQKQVQAVVKDYKLCEKALVFDPKKYAEFQAKTGAAKPQ-QQAQQQKQEK 240
            ......::.||.|:..|:..|...:.....:..|...|  |.:.|       || ..|:.:....
Human   163 PEELSALHSWFQTLSTQEPCQRAAETVLKQQGVLALRP--YLQKQ-------PQPSPAEGRAVTN 218

  Fly   241 KPKEKKEAPKKAAEPAEELDAADEALAAEP---KSKDPF------------DALPKGTFNFDDFK 290
            :|:|::.|.....|.|..:.|.::.|.:.|   ..::|.            .|||          
Human   219 EPEEEELATLSEEEIAMAVTAWEKGLESLPPLRPQQNPVLPVAGERNVLITSALP---------- 273

  Fly   291 RVYSNEDEAKSIPYFFDKFDAENYSIWFGEYKYNEELSKVFMSCNLITGMFQRLDKMRKAAFASV 355
              |.|     ::|:..:                       .:.|.|...:|.|..::|:.....:
Human   274 --YVN-----NVPHLGN-----------------------IIGCVLSADVFARYSRLRQWNTLYL 308

  Fly   356 CLFGEDGNST 365
            |...|.|.:|
Human   309 CGTDEYGTAT 318

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
eEF1gammaNP_001189308.1 GST_N_EF1Bgamma 4..79 CDD:239342 10/28 (36%)
GstA 5..187 CDD:223698 36/139 (26%)
GST_C_EF1Bgamma_like 90..209 CDD:198290 29/121 (24%)
EF1G 271..376 CDD:279041 16/107 (15%)
MARS1NP_004981.2 Thioredoxin_like <27..68 CDD:294274 8/20 (40%)
GstA <47..189 CDD:223698 41/155 (26%)
GST_C_MetRS_N 77..179 CDD:198340 28/115 (24%)
PRK12268 264..819 CDD:237029 15/95 (16%)
MetRS_core 265..633 CDD:173907 15/94 (16%)
'HIGH' region 273..283 4/26 (15%)
'KMSKS' region 593..597
Anticodon_Ia_Met 642..771 CDD:153411
MetRS_RNA 845..889 CDD:238475
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0625
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

Return to query results.
Submit another query.