DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment eEF1gamma and GstT4

DIOPT Version :9

Sequence 1:	NP_001189308.1	Gene:	eEF1gamma / 44791	FlyBaseID:	FBgn0029176	Length:	431	Species:	Drosophila melanogaster
Sequence 2:	NP_572886.2	Gene:	GstT4 / 32299	FlyBaseID:	FBgn0030484	Length:	237	Species:	Drosophila melanogaster

Alignment Length:	207	Identity:	52/207 - (25%)
Similarity:	84/207 - (40%)	Gaps:	47/207 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    54 KVPAFETAEGQYLSESNAIAYLLANEQLRGGKCP--------FVQAQVQQWISFADNEIVPASC- 109
            |:||. |..|..|||:.||...||.|:|    .|        ..::::.:::::....:..|:.
  Fly    56 KLPAI-TDHGYQLSENVAIFRHLAREKL----VPEHWYPRRHLGRSRIDEYLAWQQTNMGVATTE 115

  Fly   110 ----AWVFPLLGILPQQKNSTAKQEAEAVLQQLNQKLQ--DATFLAGERITLADIVVFSSLLHLY 168
                .|:.|.|     ||...|........:||...|.  :..||...:..:.|.:.::.|..:.
  Fly   116 YFQQKWLVPYL-----QKTRPADNAVNLASKQLEHTLNEFEQLFLNSRKFMMGDNISYADLSAIC 175

  Fly   169 EYVLEPSV-RSAFGNVN---RWFVTILNQKQVQAVVKDYKLCEKALVFDPKKYAEFQAK-TGAAK 228
            |.....|: .:||.|.|   ||:.|:..:     :...||          :...||:|| .|:..
  Fly   176 EIDQPKSIGYNAFQNRNKLARWYETVREE-----LGPHYK----------EVLGEFEAKLKGSGS 225

  Fly   229 PQQQ--AQQQKQ 238
            .|||  ||..||
  Fly   226 GQQQGVAQAVKQ 237

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
eEF1gamma	NP_001189308.1	GST_N_EF1Bgamma	4..79	CDD:239342	12/24 (50%)
		GstA	5..187	CDD:223698	36/151 (24%)
		GST_C_EF1Bgamma_like	90..209	CDD:198290	25/129 (19%)
		EF1G	271..376	CDD:279041
GstT4	NP_572886.2	GST_N_Theta	5..80	CDD:239348	12/24 (50%)
GstT4	NP_572886.2	GST_C_Theta	95..220	CDD:198292	28/144 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45459927
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0625
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.830